Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jared P. May"'
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The nonsense-mediated decay (NMD) pathway presents a challenge for RNA viruses with termination codons that precede extended 3′ untranslated regions (UTRs). The umbravirus Pea enation mosaic virus 2 (PEMV2) is a nonsegmented, positive-sens
Externí odkaz:
https://doaj.org/article/21ae92c33e2a41c88c31444319334a77
Publikováno v:
Viruses, Vol 13, Iss 4, p 646 (2021)
We report the biological and structural characterization of umbravirus-like associated RNAs (ulaRNAs), a new category of coat-protein dependent subviral RNA replicons that infect plants. These RNAs encode an RNA-dependent RNA polymerase (RdRp) follow
Externí odkaz:
https://doaj.org/article/1745b5e0366b44c3b774c42578d76790
Autor:
Molykutty J. Aryankalayil, Haaris Patel, Jared M. May, Uma Shankavaram, Michelle A. Bylicky, Shannon Martello, Sunita Chopra, Jim Axtelle, Naresh Menon, C. Norman Coleman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Radiation injury, either from radiotherapy or a mass-casualty event requires a health care system that can efficiently allocate resources to patients. We conducted a comprehensive transcriptome analysis of whole blood from a nonhuman primate
Externí odkaz:
https://doaj.org/article/6fa9f0e4d23f495d8d84d8c179897a44
Publikováno v:
Journal of the Pediatric Orthopaedic Society of North America, Vol 9, Iss , Pp 100112- (2024)
ABSTRACT: Background: Clubfoot occurs in 30% of patients with myelomeningocele (MM) and is the most frequent foot deformity in patients with arthrogryposis (ART). Patients have high recurrence rates with more conservative interventions and may requir
Externí odkaz:
https://doaj.org/article/0253bf7c63744d0a821535f9aa27b9a7
Autor:
Molykutty J. Aryankalayil, Michelle A. Bylicky, Shannon Martello, Sunita Chopra, Mary Sproull, Jared M. May, Aman Shankardass, Laurel MacMillan, Claire Vanpouille-Box, Juan Dalo, Kevin M. K. Scott, C. Norman Coleman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Radiation injury from medical, accidental, or intentional sources can induce acute and long-term hepatic dysregulation, fibrosis, and cancer. This long-term hepatic dysregulation decreases quality of life and may lead to death. Our goal in t
Externí odkaz:
https://doaj.org/article/f2be66923f7043409c1e34cc8c6aacac
Publikováno v:
Journal of Molecular Biology. :167956
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e67a14dcad6561b3dd42afcbda3854
https://doi.org/10.1016/j.jmb.2023.167956
https://doi.org/10.1016/j.jmb.2023.167956
Autor:
Jared M. May, Uma Shankavaram, Michelle A. Bylicky, Sunita Chopra, Kevin Scott, Shannon Martello, Karla Thrall, Jim Axtelle, Naresh Menon, C. Norman Coleman, Molykutty J. Aryankalayil
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract In a mass radiation exposure, the healthcare system may rely on differential expression of miRNA to determine exposure and effectively allocate resources. To this end, miRNome analysis was performed on non-human primate serum after whole tho
Externí odkaz:
https://doaj.org/article/3d867539d00642e08915a7ae9623bf71
Autor:
Molykutty J. Aryankalayil, Shannon Martello, Michelle A. Bylicky, Sunita Chopra, Jared M. May, Aman Shankardass, Laurel MacMillan, Landy Sun, Jaleal Sanjak, Claire Vanpouille-Box, Iris Eke, C. Norman Coleman
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Radiation therapy is integral to effective thoracic cancer treatments, but its application is limited by sensitivity of critical organs such as the heart. The impacts of acute radiation-induced damage and its chronic effects on no
Externí odkaz:
https://doaj.org/article/63b6648b6e304baaad201a8aeb009217
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009622 (2021)
Both cellular and viral proteins can undergo phase separation and form membraneless compartments that concentrate biomolecules. The p26 movement protein from single-stranded, positive-sense Pea enation mosaic virus 2 (PEMV2) separates into a dense ph
Externí odkaz:
https://doaj.org/article/1fa160cbc5d04bc9bf2afa384d3cf5b5
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007459 (2018)
Nonsense-mediated decay (NMD) is a host RNA control pathway that removes aberrant transcripts with long 3' untranslated regions (UTRs) due to premature termination codons (PTCs) that arise through mutation or defective splicing. To maximize coding po
Externí odkaz:
https://doaj.org/article/31a5fde05da84ad0baaeffaafd6dca21