Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jared M. Flatow"'
Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae
Autor:
Jonathan P. Staley, Jared M. Flatow, Yong Zhang, Karen S. Kim Guisbert, Erik J. Sontheimer, Simon Lin, Sara Hurtado
Publikováno v:
RNA. 18:1142-1153
Changes in transcript architecture can have powerful effects on protein expression. Regulation of the transcriptome is often dramatically revealed during dynamic conditions such as development. To examine changes in transcript architecture we analyze
Autor:
J. Carter Ralphe, Benjamin J. Soriano, Stanford T. Shulman, Julia H. Huang, Nuzhath F. Tajuddin, Kei Takahashi, Kenneth H. Rand, Jan M. Orenstein, Francesca L. Garcia, Susan C. Baker, Mitra B. Kalelkar, Simon Lin, Elizabeth J. Perlman, Jared M. Flatow, Linda M. Fox, Anne H. Rowley, Maria Tretiakova
Publikováno v:
The Journal of Infectious Diseases. 203:1021-1030
Kawasaki disease (KD) is a systemic vasculitis of young childhood that most significantly affects the coronary arteries. Although fatality rates are relatively low in countries attuned to the signs and symptoms and thus the diagnosis, the worldwide m
Autor:
Julien Ablain, David Grimwade, Sergei Doulatov, John E. Dick, Charuta Ambardekar, Jared M. Flatow, Ken I. Mills, Melanie J. McConnell, Magdalena Leiva, Jonathan D. Licht, Kim L. Rice, Itsaso Hormaeche
Publikováno v:
Blood. 114:5499-5511
The t(11;17)(q23;q21) translocation is associated with a retinoic acid (RA)–insensitive form of acute promyelocytic leukemia (APL), involving the production of reciprocal fusion proteins, promyelocytic leukemia zinc finger–retinoic acid receptor
Publikováno v:
Bioinformatics
Subjective methods have been reported to adapt a general-purpose ontology for a specific application. For example, Gene Ontology (GO) Slim was created from GO to generate a highly aggregated report of the human-genome annotation. We propose statistic
Autor:
Ji Ping Wang, Jonathan Widom, Yvonne N. Fondufe-Mittendorf, Lei Xia, Jared M. Flatow, Liqun Xi
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 11, Iss 1, p 346 (2010)
BMC Bioinformatics, Vol 11, Iss 1, p 346 (2010)
Background The nucleosome is the fundamental packing unit of DNAs in eukaryotic cells. Its detailed positioning on the genome is closely related to chromosome functions. Increasing evidence has shown that genomic DNA sequence itself is highly predict
Autor:
Aaron Golden, Thomas J. McGarry, Jonathan D. Licht, Pilib Ó Broin, Jared M. Flatow, Marianne K.H. Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(27)
WT1, a critical regulator of kidney development, is a tumor suppressor for nephroblastoma but in some contexts functions as an oncogene. A limited number of direct transcriptional targets of WT1 have been identified to explain its complex roles in tu
Autor:
Jonathan D. Licht, David Grimwade, John E. Dick, Melanie J. McConnell, Ken I. Mills, Kim L. Rice, Sergei Doulatov, Jared M. Flatow, Itsaso Hormaeche
Publikováno v:
Blood. 112:686-686
The t(11;17)(q23;q21) translocation is associated with a retinoic acid-insensitive form of acute promyelocytic leukemia (APL) involving the production of reciprocal fusion proteins PLZF-RARα and RARα-PLZF. These proteins mediate malignant transform
Autor:
Jared M. Flatow, John D. Osborne, Maria I. Danila, Warren A. Kibbe, Michelle Holko, Gang Feng, Simon Lin, Lihua Julie Zhu, Rex L. Chisholm
Publikováno v:
BMC Genomics, Vol 10, Iss Suppl 1, p S6 (2009)
BMC Genomics
BMC Genomics
Background The human genome has been extensively annotated with Gene Ontology for biological functions, but minimally computationally annotated for diseases. Results We used the Unified Medical Language System (UMLS) MetaMap Transfer tool (MMTx) to d