Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jared M Peace"'
Publikováno v:
eLife, Vol 8 (2019)
Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giv
Externí odkaz:
https://doaj.org/article/8e5d3d8620d843b8959530f3e0d9f4f2
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98501 (2014)
Chromosomal DNA replication involves the coordinated activity of hundreds to thousands of replication origins. Individual replication origins are subject to epigenetic regulation of their activity during S-phase, resulting in differential efficiencie
Externí odkaz:
https://doaj.org/article/10106477bbdd462bbc149042918c31cd
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Eukaryotic chromosomes are organized into structural and functional domains with characteristic replication timings, which are thought to contribute to epigenetic programming and genome stability. Differential replication timing results from epigenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e4b3cb8d1e9109ba306b9c727a8b6a
https://doi.org/10.1073/pnas.2212134119
https://doi.org/10.1073/pnas.2212134119
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24848ba8ed3a5ee73a66ca0edc712c13
https://elifesciences.org/articles/45512
https://elifesciences.org/articles/45512
Autor:
Jeffrey M. Jancuska, Sandra K. Villwock, Yuan Zhong, Sanket V Rege, Oscar M. Aparicio, Simon Tavaré, Tittu Nellimoottil, Janis M. Yee, Marianne Tecklenburg, Jared M. Peace, Robert A. Sclafani, Simon R.V. Knott
Publikováno v:
The Journal of Cell Biology
Cells with reduced origin firing have an increased rate of replication fork progression, whereas fork progression is slowed in cells with excess origins.
DNA damage slows DNA synthesis at replication forks; however, the mechanisms remain unclear
DNA damage slows DNA synthesis at replication forks; however, the mechanisms remain unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69b98de08698e5b08da164ea7129e34
https://doi.org/10.1083/jcb.201208060
https://doi.org/10.1083/jcb.201208060
Autor:
Simon R.V. Knott, Oscar M. Aparicio, Simon Tavaré, Jared M. Peace, Alexandra E. Rex, A. Zachary Ostrow, Christopher J. Viggiani, Yan Gan
Publikováno v:
Cell. 148(1-2):99-111
SummaryThe replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function. The characteristic initiation timing of specific origins is thought to reflect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ec0fcf73a820591439f014ebf754b3
Publikováno v:
Genome research. 26(3)
The Saccharomyces cerevisiaeForkhead Box (FOX) proteins, Fkh1 and Fkh2, regulate diverse cellular processes including transcription, long-range DNA interactions during homologous recombination, and replication origin timing and long-range origin clus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f332f10ce9c7ae554baa15e5ccafab96
https://pubmed.ncbi.nlm.nih.gov/26728715
https://pubmed.ncbi.nlm.nih.gov/26728715
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e98501 (2014)
PLoS ONE, Vol 9, Iss 5, p e98501 (2014)
Chromosomal DNA replication involves the coordinated activity of hundreds to thousands of replication origins. Individual replication origins are subject to epigenetic regulation of their activity during S-phase, resulting in differential efficiencie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dc7aa2326d60b3ef48919c31df9bc3
https://pubmed.ncbi.nlm.nih.gov/24879017
https://pubmed.ncbi.nlm.nih.gov/24879017
Autor:
Reza Kalhor, Simon R.V. Knott, Lin Chen, Yan Gan, Simon Tavaré, Zachary A. Ostrow, Jared M. Peace, Oscar M. Aparicio
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a22bc7d9f58a71f31fbb44ca4982371
https://doi.org/10.1096/fasebj.27.1_supplement.200.1
https://doi.org/10.1096/fasebj.27.1_supplement.200.1