Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jared M, Fischer"'
Autor:
Sinan Sabuncu, Jose Montoya Mira, Arnaud Quentel, Michelle M. Gomes, Fehmi Civitci, Jared M. Fischer, Adem Yildirim
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 2, Pp n/a-n/a (2023)
Abstract Surface‐engineered hydrophobic nanoparticles that can stabilize small gas pockets on their surfaces (i.e., gas‐stabilizing nanoparticles, GSNs) have been recently shown to be excellent contrast and cavitation agents for ultrasound theran
Externí odkaz:
https://doaj.org/article/6bb510f47d1044b1826edc5fd415b646
Autor:
Jose Montoya Mira, Ajay A. Sapre, Brett S. Walker, Jesus Bueno Alvarez, Kyle T. Gustafson, Eugene Tu, Jared M. Fischer, Melissa H. Wong, Sadik Esener, Yu-Jui Chiu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and
Externí odkaz:
https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa64
Autor:
Matthew S. Dietz, Thomas L. Sutton, Brett S. Walker, Charles E. Gast, Luai Zarour, Sidharth K. Sengupta, John R. Swain, Jennifer Eng, Michael Parappilly, Kristen Limbach, Ariana Sattler, Erik Burlingame, Yuki Chin, Austin Gower, Jose L. Montoya Mira, Ajay Sapre, Yu-Jui Chiu, Daniel R. Clayburgh, SuEllen J. Pommier, Jeremy P. Cetnar, Jared M. Fischer, Jerry J. Jaboin, Rodney F. Pommier, Brett C. Sheppard, V. Liana Tsikitis, Alison H. Skalet, Skye C. Mayo, Charles D. Lopez, Joe W. Gray, Gordon B. Mills, Zahi Mitri, Young Hwan Chang, Koei Chin, Melissa H. Wong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Metastatic progression defines the final stages of tumor evolution and underlies the majority of cancer-related deaths. The heterogeneity in disseminated tumor cell populations capable of seeding and growing in distant organ sites contribute
Externí odkaz:
https://doaj.org/article/5b2e471d1c8144e4a081a30d60ac23cd
Autor:
Hillary H. Le, Suleyman S. Cinaroglu, Elise C. Manalo, Aysegul Ors, Michelle M. Gomes, Burcin Duan Sahbaz, Karla Bonic, Carlos A. Origel Marmolejo, Arnaud Quentel, Justin S. Plaut, Taryn E. Kawashima, E. Sila Ozdemir, Sanjay V. Malhotra, Yavuz Ahiska, Ugur Sezerman, Gunseli Bayram Akcapinar, Joshua C. Saldivar, Emel Timucin, Jared M. Fischer
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103646- (2021)
Background: Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice. Cancer is an age-associated disease an
Externí odkaz:
https://doaj.org/article/e47bd46165a546c3a103052aa9b58199
Autor:
Kyle T. Gustafson, Negin Mokhtari, Elise C. Manalo, Jose Montoya Mira, Austin Gower, Ya-San Yeh, Mukanth Vaidyanathan, Sadik C. Esener, Jared M. Fischer
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 143 (2022)
Some cancer cells rely heavily on non-essential biomolecules for survival, growth, and proliferation. Enzyme based therapeutics can eliminate these biomolecules, thus specifically targeting neoplastic cells; however, enzyme therapeutics are susceptib
Externí odkaz:
https://doaj.org/article/34ccfc803a1d463782269c14388b67eb
Publikováno v:
Nano Letters. 23:659-666
Localization-based ultrasound imaging methods that use microbubbles or nanodroplets offer high-resolution imaging with improved sensitivity and reduced background signal. However, these methods require long acquisition times (typically seconds to min
Publikováno v:
Molecular Cancer Therapeutics. 21:1846-1856
Tumor protein p63 (TP63) is a member of the TP53 protein family that are important for development and in tumor suppression. Unlike TP53, TP63 is rarely mutated in cancer, but instead different TP63 isoforms regulate its activity. TA isoforms (TAp63)
Supplementary Data from Computational Modeling of TP63–TP53 Interaction and Rational Design of Inhibitors: Implications for Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f1ab43e9e0a03ca134125c524cf387
https://doi.org/10.1158/1535-7163.22523334
https://doi.org/10.1158/1535-7163.22523334
Autor:
Yu-Jui Chiu, Eugene Tu, Sadik C. Esener, Ajay Sapre, Kyle T. Gustafson, Jesus Bueno Alvarez, Brett S. Walker, Melissa H. Wong, Jared M. Fischer, Jose L. Montoya Mira
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology
Communications Biology
Cellular circulating biomarkers from the primary tumor such as circulating tumor cells (CTCs) and circulating hybrid cells (CHCs) have been described to harbor tumor-like phenotype and genotype. CHCs are present in higher numbers than CTCs supporting
Autor:
Nicholas R. Smith, Sidharth K. Sengupta, Patrick Conley, Nicole R. Giske, Christopher Klocke, Brett Walker, Noelle McPhail, John R. Swain, Yeon Jung Yoo, Ashley Anderson, Paige S. Davies, Nasim Sanati, Theresa N. Nguyen, Kristof Torkenczy, Andrew C. Adey, Jared M. Fischer, Guanming Wu, Melissa H. Wong
SummaryIntestinal development, response to injury and disease states rely upon balanced stem cell proliferation. Historically, two subtypes of intestinal epithelial stem cells (ISCs)—slow-cycling/label-retaining, and actively-cycling/canonical Wnt-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9631735afe35afa6d294c379e38d1a96
https://doi.org/10.1101/2022.09.30.509798
https://doi.org/10.1101/2022.09.30.509798