Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jared L. Dietze"'
Autor:
Jared L. Dietze, Daniel A. Rothenberg, Terri A. Addona, Antoine Boudot, Jessica Kohler, Jennifer G. Abelin, Vikram R. Juneja, Paul J. Turcott, Brandon P. Conn, Marit M. van Buuren, Scott P. Goulding, Christopher D. McGann, Richard B. Gaynor, John R. Srouji, Kendra C. Foley, Jae Won Choi, Michael S. Rooney, Divya Lenkala
Publikováno v:
Cell Reports Methods. 1:100084
Summary Oncogenic mutations in KRAS can be recognized by T cells on specific class I human leukocyte antigen (HLA-I) molecules, leading to tumor control. To date, the discovery of T cell targets from KRAS mutations has relied on occasional T cell res
Autor:
Vikram R. Juneja, Terri A. Addona, John Srouji, Jae Won Choi, Michael S. Rooney, Brandon P. Conn, Paul J. Turcott, Christopher D. McGann, Jennifer G. Abelin, Richard B. Gaynor, Antoine Boudot, Marit M. van Buuren, Scott P. Goulding, Jessica Kohler, Divya Lenkala, Daniel A. Rothenberg, Jared L. Dietze
Publikováno v:
Cancer Research. 80:PO-015
Response rates to immunotherapies in pancreatic ductal adenocarcinoma (PDAC) patients are low. However, cases with long-term survival have been correlated with both T cell infiltration and quality of neoantigens (i.e., epitopes from mutations present