Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jared Kay"'
1
LC–MS/MS assay for N1-methylnicotinamide in humans, an endogenous probe for renal transporters
Autor: Jenny Zhang, Lina Luo, Christopher Banfield, Christopher L Holliman, A. David Rodrigues, Jared Kay, Ragu Ramanathan, Martin E. Dowty
Publikováno v: Bioanalysis. 10:673-689
Background: N1-methylnicotinamide (1-NMN) has been proposed as a potential clinical biomarker to assess drug–drug interactions involving organic cation transporters (OCT2) and multidrug and toxin extrusion protein transporters. Results: A hydrophil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a483f9b9f986f79806703bd89d9c749a
https://doi.org/10.4155/bio-2017-0272
Zobrazit plný text záznamu
2
Cigarette Smoke-Induced Alterations in Frontal White Matter Lipid Profiles Demonstrated by MALDI-Imaging Mass Spectrometry: Relevance to Alzheimer’s Disease
Autor: Suzanne M. de la Monte, Ming Tong, Alexander Krotow, Jared Kay, Amit R Agarwal, Enrique Cadenas, Kavin M Nunez
Publikováno v: Journal of Alzheimer's Disease. 51:151-163
BACKGROUND Meta-analysis has shown that smokers have significantly increased risks for Alzheimer's disease (AD), and neuroimaging studies showed that smoking alters white matter (WM) structural integrity. OBJECTIVE Herein, we characterize the effects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2b025c6b520856eb2433b224f663e5
https://doi.org/10.3233/jad-150916
Zobrazit plný text záznamu
3
LC-MS/MS assay for N
Autor: Lina, Luo, Jared, Kay, Jenny, Zhang, Christopher L, Holliman, A David, Rodrigues, Martin, Dowty, Christopher, Banfield, Ragu, Ramanathan
Publikováno v: Bioanalysis. 10(9)
NA hydrophilic interaction liquid chromatography-MS/MS assay, to quantify 1-NMN, in human plasma and urine is reported.A hydrophilic interaction chromatography (HILIC)-tandem mass spectrometry (MS/MS) assay to quantify 1-NMN in human plasma and urine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cb6479651cf5402a022f2a5e698ce545
https://pubmed.ncbi.nlm.nih.gov/29749253
Zobrazit plný text záznamu
4
Imaging mass spectrometry of frontal white matter lipid changes in human alcoholics
Autor: Jillian J. Kril, Jared Kay, Greg T. Sutherland, Suzanne M. de la Monte, Donna Sheedy, Emine B. Yalcin
Background Chronic alcohol use disorders (AUD) are associated with white matter (WM) degeneration with altered myelin integrity. Matrix assisted laser desorption ionization-imaging mass spectrometry (MALDI-IMS) enables high throughput analysis of mye
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7180bee1d6442099211aa039b8967fc3
https://hdl.handle.net/2123/19691
Zobrazit plný text záznamu
5
Comparative Analysis of Lipid Extracts and Imaging Mass Spectrometry for Evaluating Cerebral White Matter Biochemical Pathology in an Experimental Second-Hand Cigarette Smoke Exposure Model
Autor: Suzanne M. de la Monte, Jared Kay, Emine B. Yalcin, er Krotow, Alex
Publikováno v: Mass spectrometry & purification techniques
Background: White matter injury and degeneration are common features of developmental and aging-associated diseases, yet their pathobiological bases are poorly understood. However, recent advances in Matrix-Assisted Laser Desorption Ionization (MALDI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3ac8c30742163d62630fb224cb4fd9
https://pubmed.ncbi.nlm.nih.gov/29226272
Zobrazit plný text záznamu
6
Ethanol-Induced White Matter Atrophy Is Associated with Impaired Expression of Aspartyl-Asparaginyl-β-Hydroxylase (ASPH) and Notch Signaling in an Experimental Rat Model
Autor: Billy Gotama, Howard Gonzalez-Navarrete, Suzanne M. de la Monte, Ming Tong, Jared Kay, Tyler Kirchberg, Emine B. Yalcin
Publikováno v: Journal of drug and alcohol research
Alcohol-induced white matter (WM) degeneration is linked to cognitive-motor deficits and impairs insulin/insulin-like growth factor (IGF) and Notch networks regulating oligodendrocyte function. Ethanol downregulates Aspartyl-Asparaginyl-β-Hydroxylas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fed353a0b2d854879c3afe360db3d57
http://europepmc.org/articles/PMC5711436
Zobrazit plný text záznamu
7
Altered Temporal Lobe White Matter Lipid Ion Profiles in an Experimental Model of Sporadic Alzheimer;s Disease
Autor: Alexander Krotow, Jared Kay, Suzanne M. de la Monte, Gina V. Vimbela, Ming Tong, Raiane Leão, Emine B. Yalcin
Background White matter is an early and important yet under-evaluated target of Alzheimer's disease (AD). Metabolic impairments due to insulin and insulin-like growth factor resistance contribute to white matter degeneration because corresponding sig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b0e10b9d19090e2a9b4c49ff4e8d98
https://europepmc.org/articles/PMC5507369/
Zobrazit plný text záznamu
9
Tobacco Smoke-Induced Alterations in Hepatic Lipid Profiles Demonstrated by Imaging Mass Spectrometry
Autor: Kavin M Nunez, Amit R Agarwal, Jared Kay, Ming Tong, Emine B. Yalcin, Enrique Cadenas, Suzanne M. de la Monte
Publikováno v: Mass Spectrometry & Purification Techniques.
To account for differences in susceptibility to alcoholic liver disease (ALD), tobacco smoking should be evaluated as a potential cofactor given the very high percentage of heavy drinkers also smoke, and the NNK tobacco-specific nitrosamine was shown
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56322e0ef6c3f0c8da5c40191786832d
https://doi.org/10.4172/2469-9861.1000112
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje