Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jared H. Rowe"'
Autor:
Sanya Thomas, Geoffrey Guenther, Jared H. Rowe, Craig D. Platt, Akiko Shimamura, Ofer Levy, Lakshmi Ganapathi
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Severe congenital neutropenia caused by jagunal homolog 1 (JAGN1) mutation is a rare condition resulting from maturation arrest secondary to endoplasmic reticulum stress response from impaired neutrophil protein glycosylation. Here, we report a case
Externí odkaz:
https://doaj.org/article/6bee8d4495b94aa783dc4859f020c704
Autor:
Nina B. Gold, Steven M. Harrison, Jared H. Rowe, Jessica Gold, Elissa Furutani, Alessandra Biffi, Christine N. Duncan, Akiko Shimamura, Leslie E. Lehmann, Robert C. Green
Publikováno v:
HGG Advances, Vol 3, Iss 1, Pp 100059- (2022)
Summary: Hematopoietic stem cell transplant (HSCT) can prevent progression of several genetic disorders. Although a subset of these disorders are identified on newborn screening panels, others are not identified until irreversible symptoms develop. G
Externí odkaz:
https://doaj.org/article/459ce8e8d0e049c39862d627d3f35655
Autor:
Satyaki Sengupta, Sanjukta Das, Angela C. Crespo, Annelisa M. Cornel, Anand G. Patel, Navin R. Mahadevan, Marco Campisi, Alaa K. Ali, Bandana Sharma, Jared H. Rowe, Hao Huang, David N. Debruyne, Esther D. Cerda, Malgorzata Krajewska, Ruben Dries, Minyue Chen, Shupei Zhang, Luigi Soriano, Malkiel A. Cohen, Rogier Versteeg, Rudolf Jaenisch, Stefani Spranger, Rizwan Romee, Brian C. Miller, David A. Barbie, Stefan Nierkens, Michael A. Dyer, Judy Lieberman, Rani E. George
Publikováno v:
Nat Cancer
Apart from the anti-GD2 antibody, immunotherapy for neuroblastoma has had limited success due to immune evasion mechanisms, coupled with an incomplete understanding of predictors of response. Here, from bulk and single-cell transcriptomic analyses, w
Autor:
Christine Duncan, Jared H. Rowe, Jessica Gold, Akiko Shimamura, Elissa Furutani, Nina B. Gold, Leslie Lehmann, Robert C. Green, Steven M. Harrison, Alessandra Biffi
Publikováno v:
Molecular Genetics and Metabolism. 132:S326-S328
Autor:
Satyaki Sengupta, Sanjukta Das, Angela C. Crespo, Annelisa M. Cornel, Anand G. Patel, Navin R. Mahadevan, Marco Campisi, Alaa K. Ali, Bandana Sharma, Jared H. Rowe, Rogier Versteeg, Rudolf Jaenisch, Stefani Spranger, Rizwan Romee, Brian C. Miller, David A. Barbie, Stefan Nierkens, Michael A. Dyer, Judy Lieberman, Rani E. George
Publikováno v:
Cancer Immunology Research. 10:A08-A08
Active immunotherapy approaches for neuroblastoma (NB), a pediatric cancer of the sympathetic nervous system, has met with limited success. Especially challenging is the genetic heterogeneity of NB which makes it difficult to identify factors that co
Autor:
Ilaria Elia, Jared H. Rowe, Sheila Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi, Sarah Weiss, Gordon J. Freeman, Arlene H. Sharpe, Marcia C. Haigis
Publikováno v:
Cell metabolism. 34(8)
The tumor microenvironment (TME) is a unique metabolic niche that can inhibit T cell metabolism and cytotoxicity. To dissect the metabolic interplay between tumors and T cells, we establish an in vitro system that recapitulates the metabolic niche of
Autor:
Ilaria Elia, Giulia Notarangelo, Marcia C. Haigis, Sheila E. Johnson, Shakchhi Joshi, Gordon J. Freeman, Kiran Kurmi, Jared H. Rowe, Arlene H. Sharpe
Publikováno v:
SSRN Electronic Journal.
The tumor microenvironment (TME) is a unique metabolic niche that can inhibit CD8+ T cell metabolism and cytotoxic activity. It has been a challenge to dissect the metabolic interplay between tumors and T cells. Consequently, the mechanisms whereby t
Autor:
Luigi D. Notarangelo, Jared H. Rowe, Boaz Palterer, Riccardo Castagnoli, Ottavia M. Delmonte, Adam K. Dobbs
Publikováno v:
J Clin Immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1c8cdaa04d3da15da4738cbc463e4c
https://europepmc.org/articles/PMC8319810/
https://europepmc.org/articles/PMC8319810/
Autor:
Jaime L. Schneider, Jared H. Rowe, Carla F. Kim, Carolina Garcia-de-Alba, Marcia C. Haigis, Arlene H. Sharpe
Publikováno v:
Cell. 184(8)
The population is aging at a rate never seen before in human history. As the number of elderly adults grows, it is imperative we expand our understanding of the underpinnings of aging biology. Human lungs are composed of a unique panoply of cell type
Autor:
Jessica Gold, Steven M. Harrison, Nina B. Gold, Akiko Shimamura, Robert C. Green, Alessandra Biffi, Leslie Lehmann, Christine Duncan, Elissa M. Furutani, Jared H. Rowe
Publikováno v:
Human Genetics and Genomics Advances
HGG Advances, Vol 3, Iss 1, Pp 100059-(2022)
HGG Advances, Vol 3, Iss 1, Pp 100059-(2022)
Summary Hematopoietic stem cell transplant (HSCT) can prevent progression of several genetic disorders. Although a subset of these disorders are identified on newborn screening panels, others are not identified until irreversible symptoms develop. Ge