Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact.

Autor: Puya G Yazdi, Brian A Pedersen, Jared F Taylor, Omar S Khattab, Yu-Han Chen, Yumay Chen, Steven E Jacobsen, Ping H Wang

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0136574 (2015)

Deciphering the multitude of epigenomic and genomic factors that influence the mutation rate is an area of great interest in modern biology. Recently, chromatin has been shown to play a part in this process. To elucidate this relationship further, we

Externí odkaz: https://doaj.org/article/5a6edefd18dc471991efb89152a27adb

Effects of Arthrocen, an avocado/soy unsaponifiables agent, on inflammatory mediators and gene expression in human chondrocytes

Autor: Brian Pedersen, Ramin Goudarzi, Jared F. Taylor, Puya G. Yazdi

Publikováno v: FEBS Open Bio

Osteoarthritis (OA) is a chronic joint disease characterized by pain and stiffness. Recently, there has been great interest in the use of plant‐derived compounds and supplements in managing the symptoms of OA. Arthrocen is a plant‐based supplemen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7288b44de0eba40f2089c25b3e649f8b
https://doi.org/10.1002/2211-5463.12176

Contributors

Autor: Ahmed M. Abdel-Azeem, Mohamed A. Abdel-Azeem, Wan Mohd Aizat, Khokon Miah Akanda, Abdelwahab A. Alsenosy, Luana Barbosa Correa, Katarina Bauerova, Rodney L. Benjamin, Prakash S. Bisen, Richard J. Bloomer, Matthew Butawan, Matthew Cheesman, Hymie Chera, Flavia M. Cicuttini, Ian Edwin Cock, Zhaoli Dai, Jonathan Daich, Harman Dhanoa, Palani Dinesh, Meenal Dixit, David T. Felson, Neda Ghamarzad Shishavan, Reza Ghiasvand, Sumit Govil, Ramesh K. Goyal, Maria das Graças Henriques, Sultana Monira Hussain, Indrani Jadhav, Rohini Karunakaran, Diyathi Tharindhi Karunaratne, Waleed F. Khalil, Viera Kuncirova, Yuan Z. Lim, Santram Lodhi, Michel Mansur Machado, Eliana Mariño, Ili Natasya Marzaimi, Justice Mbizo, Keiran H. McLeod, Maryam Miraghajani, Menachem Nagar, Mukesh Nandave, Shreesh Ojha, Anthony Okafor, Siriwan Ongchai, Vikas Pandey, Arzoo Pannu, Shalini Pareek, Kanika Patel, Dinesh Kumar Patel, G.M. Masud Parvez, Brian A. Pedersen, Pathirage Kamal Perera, Silvester Ponist, Bahram Pourghassem Gargari, Jerzy A. Przyborowski, Kilambi Pundarikakshudu, Mahaboobkhan Rasool, James L. Richards, Elaine Cruz Rosas, Yitzhak Rosen, Srikumar Padmalayam Sadanandan, Hazem M. Shaheen, Divya Shrivastava, Rajesh Shukla, Lukas Slovak, Luís Flávio Souza de Oliveira, Leauna M. Stone, Vetriselvan Subramaniyan, Paweł Sulima, Melanie A. Sutton, Jared F. Taylor, Angélica Thomaz Vieira, Gautam P. Vadnere, Maryam Vahedi, Marie van der Merwe, Marco Aurélio Ramirez Vinolo, Yuanyuan Wang, Yu Anne Yap, Puya G. Yazdi, Swan Sim Yeap, Luísa Zuravski

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e57ee556c8b92cf4a0bd7cf42243a3a1
https://doi.org/10.1016/b978-0-12-813820-5.09994-3

Hepatic proteomic analysis revealed altered metabolic pathways in insulin resistant Akt1(+/-)/Akt2(-/-) mice

Autor: Weiwen Wang, Ping H. Wang, Omar S. Khattab, Puya G. Yazdi, Robert Edwards, Jared F. Taylor, Yu-Han Chen, Brian Pedersen

Publikováno v: Metabolism: clinical and experimental, vol 64, iss 12

Objective The aim of this study was to identify liver proteome changes in a mouse model of severe insulin resistance and markedly decreased leptin levels. Methods Two-dimensional differential gel electrophoresis was utilized to identify liver proteom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e55f058d53c3ad5294ef22a4f52ef2
https://escholarship.org/uc/item/36j257kt

Novel remodeling of the mouse heart mitochondrial proteome in response to acute insulin stimulation

Autor: Brian Pedersen, Jared F. Taylor, Yumay Chen, Puya G. Yazdi, Omar S. Khattab, Yu-Han Chen, Ping H. Wang

Publikováno v: Nutrition, metabolism, and cardiovascular diseases : NMCD, vol 25, iss 12

Background and Aim Mitochondrial dysfunction contributes to the pathophysiology of diabetic cardiomyopathy. The aim of this study was to investigate the acute changes in the mitochondrial proteome in response to insulin stimulation. Methods and Resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249aaa10f6cb8efcfb3732616b044cf6
https://pubmed.ncbi.nlm.nih.gov/26610654