Výsledky vyhledávání - "Jared Delahaye"

Bepirovirsen, antisense oligonucleotide (ASO) against hepatitis B virus (HBV), harbors intrinsic immunostimulatory activity via Toll-like receptor 8 (TLR8) preclinically, correlating with clinical efficacy from the Phase 2a study

Autor: Shihyun You, Jared Delahaye, Megan Ermler, Jennifer Singh, William Jordan, Avijit Ray, Nicholas Galwey, Daren Austin, Dickens Theodore, Melanie Paff

Publikováno v: Journal of Hepatology. 77:S873-S874

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7406f0f5e26859830cf1ad14860d6ec
https://doi.org/10.1016/s0168-8278(22)02041-4

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Combination treatment of a PAPD5/7 inhibitor with an antisense oligonucleotide bepirovirsen with concurrent dosing shows additive HBsAg decreases in the AAV-HBV mouse model

Autor: Jared Delahaye, Edward Long, Chi Lau, Jacob Parsons, Bo Wen, Zhiyi Cui, Melanie Paff, Shihyun You, Martin Leivers

Publikováno v: Journal of Hepatology. 77:S880

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae8afe669c9b8f4b9dbe6b92ea52dc74
https://doi.org/10.1016/s0168-8278(22)02053-0

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A blood-based transcriptional signature in a novel murine tuberculosis model predicts risk of human tuberculosis progression

Autor: Courtney R. Plumlee, Benjamin H. Gern, Fergal J. Duffy, Jared Delahaye, Tige R. Rustad, John D. Aitchison, David R. Sherman, Daniel E. Zak, Michael Y. Gerner, Kevin B. Urdahl

Publikováno v: The Journal of Immunology. 200:117.43-117.43

Tuberculosis (TB) is a highly heterogeneous human disease that develops in a subset of individuals who inhale Mycobacterium tuberculosis (Mtb). Using advanced machine-learning algorithms, we discovered a blood transcriptional signature that identifie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::197d79dab2b5dba6cf8c27b4e5e9caf3
https://doi.org/10.4049/jimmunol.200.supp.117.43

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Alveolar and monocyte-derived macrophages differentially engage antibacterial programs during adaptive immunity to Mycobacterium tuberculosis

Autor: Jared Delahaye, Courtney R. Plumlee, Christopher Plaisier, Nitin Baliga, David R. Sherman, Kevin B. Urdahl

Publikováno v: The Journal of Immunology. 200:173.12-173.12

Cognate interactions between antigen-specific CD4 T cells and Mycobacterium tuberculosis (Mtb)-infected cells are critical for mucosal immunity to tuberculosis (TB). However, Mtb resides intracellularly within a variety of myeloid cell populations, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54456be7dae10e338caabb46ca970657
https://doi.org/10.4049/jimmunol.200.supp.173.12

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