Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jared Addison Cotta"'
Autor:
Junaid Arshad, Brian A. Pico, Jared Addison Cotta, Deukoo Kwon, Ali Roberts, Jonathan C. Trent, Jibran Ahmed
Publikováno v:
JCO Precision Oncology. :66-73
PURPOSE GI stromal tumor (GIST) is the most common sarcoma of the GI tract. Management of patients with GIST is determined by KIT, PDGFRA, or other genomic alterations. Tissue-based next-generation sequencing (NGS) analysis is the standard approach f
Autor:
Timothy L. Cannon, Ramya Thota, Nicole D. Fleming, Susan Halabi, Ricardo H. Alvarez, Jared Addison Cotta, Pam K. Mangat, Carmen Julia Calfa, Pamela A. Crilley, Sasha L. Warren, Andrew L. Rygiel, Theodore Pollock, Dan Veljovich, Elizabeth Garrett-Mayer, Julian C. Schink, Tareq Al Baghdadi, Julie Gottlieb Fisher, David Tait, Richard L. Schilsky
Publikováno v:
Targeted Oncology. 15:733-741
The Targeted Agent and Profiling Utilization Registry (TAPUR) Study, a phase II basket study, evaluates anti-tumor activity of commercially available targeted agents in patients with advanced cancers harboring genomic alterations known as drug target
Publikováno v:
Journal of Clinical Oncology. 38:e21547-e21547
e21547 Background: While genetic profiling has become standard of care for patients diagnosed with non-small cell lung cancer (NSCLC), next-generation sequencing (NGS) provides a wealth of information about targetable mutations. Advances in genetic t
Publikováno v:
Journal of Clinical Oncology. 38:e15135-e15135
e15135 Background: While the use of monoclonal antibodies targeting the PD-1 axis in metastatic non-small cell lung cancer (NSCLC) continues to expand since initial FDA approval in 2015, factors predictive of response still remain to be determined. M
Publikováno v:
Journal of Clinical Oncology. 38:4642-4642
4642 Background: he KRAS proto-oncogene is involved in the RAS/MAPK pathway. Various G12X mutations have been examined with the most common mutations being G12D (40%), G12V (30%), and G12R (15-20%) in pancreatic cancer patients. Throughout the course
Autor:
Elizabeth Garrett-Mayer, Julie Gottlieb Fisher, Timothy L. Cannon, Pam K. Mangat, Ricardo H. Alvarez, Samiha Islam, Susan Halabi, Andrew L. Rygiel, Kaitlyn R. Antonelli, Theodore Pollock, Suanna S. Bruinooge, Richard L. Schilsky, Jared Addison Cotta, Pamela A. Crilley, Tareq Al Baghdadi
Publikováno v:
Cancer Research. 79:CT135-CT135
Background: The TAPUR Study is a phase II multi-basket study that evaluates the anti-tumor activity of commercially available targeted agents in pts with advanced cancers with genomic alterations known to be drug targets. Results in two cohorts of BC
Publikováno v:
Journal of Clinical Oncology. 37:11044-11044
11044 Background: Leiomyosarcoma is a malignant mesenchymal tumor of cells of smooth muscle lineage arising commonly in retroperitoneum, uterus, large veins, and the limbs. In contrast to many sarcomas, the genetics of leiomyosarcomas are complex and
Autor:
Vasanti M. Jhaveri, Marilyn Huang, Brian M. Slomovitz, Jared Addison Cotta, Sophia George, Dino Fanfan
Publikováno v:
Journal of Clinical Oncology. 37:e17098-e17098
e17098 Background: Next Generation Sequencing (NGS) guides targeted therapy and clinical trial enrollment for patients with gynecologic malignancies. South Florida is a key region to explore biomarkers and molecular alterations common in Hispanic (H)
Publikováno v:
Journal of Clinical Oncology. 36:e24179-e24179
e24179Background: The landscape of precision oncology is constantly changing. Cancer centers in both the academic and community settings have been implementing Molecular Tumor Boards (MTB) to suppo...
Publikováno v:
Journal of Clinical Oncology. 36:12071-12071
12071Background: Academic Medical Centers (AMC) and community practices are implementing Molecular Tumor Boards (MTB) to interpret next-generation sequencing (NGS) results and develop clinical guid...