Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jared A.M. Bard"'
Publikováno v:
Molecular Cell. 82:2544-2556
Stress-induced condensation of mRNA and protein into massive cytosolic clusters is conserved across eukaryotes. Known as stress granules when visible by imaging, these structures remarkably have no broadly accepted biological function, mechanism of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b196895e6234a2e17eb2557983bf65d1
https://doi.org/10.1016/j.molcel.2022.05.014
https://doi.org/10.1016/j.molcel.2022.05.014
SUMMARYThe 26S proteasome is the major ATP-dependent protease in eukaryotic cells, where it catalyzes the degradation of thousands of proteins for general homeostasis and the control of vital processes. It specifically recognizes appropriate substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1a8dcd097697970b4b02e7c399ff82
https://doi.org/10.1101/2021.08.18.456915
https://doi.org/10.1101/2021.08.18.456915
Publikováno v:
SSRN Electronic Journal.
Heat shock triggers formation of intracellular protein aggregates and induction of a molecular disaggregation system. Although this system (Hsp100/Hsp70/Hsp40 in most cellular life) can disperse aggregates of model misfolded proteins, its activity on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a2c94e57a51e5aa5d93a8f97aa0ff1
https://doi.org/10.2139/ssrn.3957615
https://doi.org/10.2139/ssrn.3957615
Publikováno v:
Annual Review of Biochemistry. 87:697-724
As the endpoint for the ubiquitin-proteasome system, the 26S proteasome is the principal proteolytic machine responsible for regulated protein degradation in eukaryotic cells. The proteasome's cellular functions range from general protein homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9645c40599ea9e4de85456c1375f6dc1
https://doi.org/10.1146/annurev-biochem-062917-011931
https://doi.org/10.1146/annurev-biochem-062917-011931
Autor:
Andreas Martin, Jared A.M. Bard
Publikováno v:
Methods in Molecular Biology ISBN: 9781493987054
The 26S proteasome is the major regulated protease in eukaryotes and is responsible for degrading ubiquitinated substrates. It consists of a barrel-shaped 20S core peptidase and one or two 19S regulatory particles, which recognize, unfold, and transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7c84b81c37312ae9f1ad46d23f574c
https://pubmed.ncbi.nlm.nih.gov/30242713
https://pubmed.ncbi.nlm.nih.gov/30242713
Publikováno v:
Cell. 177(2)
The 26S proteasome is the principal macromolecular machine responsible for protein degradation in eukaryotes. However, little is known about the detailed kinetics and coordination of the underlying substrate-processing steps of the proteasome, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bc77e79662be58af8e748090e8e0d4
https://pubmed.ncbi.nlm.nih.gov/30929903
https://pubmed.ncbi.nlm.nih.gov/30929903
Autor:
Jared A.M. Bard, Ellen A. Goodall, Andreas Martin, Erika Lopez-Alfonzo, Ken C. Dong, Erik Jonsson
Publikováno v:
Biophysical Journal. 116:158a-159a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::618e73c8e37135b130c95b21015ce87d
https://doi.org/10.1016/j.bpj.2018.11.878
https://doi.org/10.1016/j.bpj.2018.11.878
Publikováno v:
The FASEB Journal. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0edc8b8555a5654cd951f64ae4e5f69
https://doi.org/10.1096/fasebj.30.1_supplement.597.2
https://doi.org/10.1096/fasebj.30.1_supplement.597.2