Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jared A. Gatto"'
Autor:
Samantha J. Tener, Zhi Lin, Scarlet J. Park, Kairaluchi Oraedu, Matthew Ulgherait, Emily Van Beek, Andrés Martínez-Muñiz, Meghan Pantalia, Jared A. Gatto, Julia Volpi, Nicholas Stavropoulos, William W. Ja, Julie C. Canman, Mimi Shirasu-Hiza
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Mutations in Cullin-3 (Cul3), a conserved gene encoding a ubiquitin ligase, are strongly associated with autism spectrum disorder (ASD). Here, we characterize ASD-related pathologies caused by neuron-specific Cul3 knockdown in Drosophila. We
Externí odkaz:
https://doaj.org/article/0395efbca1cc46338d7654c16c827527
Autor:
Samantha J. Tener, Jared A. Gatto, Matt Ulgherait, Julie C. Canman, Scarlet J. Park, Julia Siewert, William W. Ja, Naomi Klickstein, Adil M. Midoun, Mimi Shirasu-Hiza
Publikováno v:
Nature. 598:353-358
Time-restricted feeding (TRF) has recently gained interest as a potential anti-ageing treatment for organisms from Drosophila to humans1–5. TRF restricts food intake to specific hours of the day. Because TRF controls the timing of feeding, rather t
A Complex Relationship between Immunity and Metabolism in Drosophila Diet-Induced Insulin Resistance
Autor:
Jared A. Gatto, Jill L. Fink, Ana R. Grant, Thomas J. Baranski, Laura Palanker Musselman, Bryon F. Tuthill
Publikováno v:
Molecular and Cellular Biology. 38
Both systemic insulin resistance and tissue-specific insulin resistance have been described in Drosophila and are accompanied by many indicators of metabolic disease. The downstream mediators of insulin-resistant pathophysiology remain unclear. We an
Autor:
Michael R. Brent, Jared A. Gatto, Ezekiel J. Maier, Jill L. Fink, Thomas J. Baranski, Laura Palanker Musselman
Publikováno v:
Genetics. 208(4)
Musselman et al. address the overarching question: “What’s so bad about a high-calorie diet?” Using computational biology to analyze mRNA expression profiles, the authors built a Drosophila fat body gene regulatory network that predicted... Ins