Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jared, Gollob"'
Autor:
Teresa Coelho, David Adams, Isabel Conceição, Márcia Waddington-Cruz, Hartmut H. Schmidt, Juan Buades, Josep Campistol, John L. Berk, Michael Polydefkis, Jing Jing Wang, Jihong Chen, Marianne T. Sweetser, Jared Gollob, Ole B. Suhr
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Patisiran, an RNA interference therapeutic, has demonstrated robust reduction of wild-type and mutant transthyretin protein and was able to improve polyneuropathy and quality of life following 18 months of treatment in patients wi
Externí odkaz:
https://doaj.org/article/043b3f0175b643a0af6f21c8079884d9
Autor:
Bin Yang, Jared Gollob, Joyoti Dey, Phillip Liu, Michele Mayo, Rahul Karnik, Vaishali Dixit, Jieun Jeong, Chris De Savi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/607daf0f471d4bd5b8805a1d7a4a8e04
Publikováno v:
Precision Cancer Therapies, Volume 1 ‐ Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies. :372-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c20ba92b02494c173f546445ec3075f
https://doi.org/10.1002/9781119819950.ch26
https://doi.org/10.1002/9781119819950.ch26
Autor:
David Adams, Ole B. Suhr, Peter J. Dyck, William J. Litchy, Raina G. Leahy, Jihong Chen, Jared Gollob, Teresa Coelho
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Patisiran is an investigational RNA interference (RNAi) therapeutic in development for the treatment of hereditary ATTR (hATTR) amyloidosis, a progressive disease associated with significant disability, morbidity, and mortality. M
Externí odkaz:
https://doaj.org/article/af4683532dd9463a8cea7c211ead29bc
Autor:
Stephen D Smith, Alexander Starodub, Don A. Stevens, Aditi Shastri, Pierluigi Porcu, Tatyana Feldman, Reggie Ewesuedo, Chris DeSavi, Joyoti Dey, Sagar Agarwal, Sean Donohue, Rachelle Perea, Christine Klaus, Jared Gollob
Publikováno v:
Blood. 140:12024-12025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4d2bc9c55a514efeb9079a78abf7ac
https://doi.org/10.1182/blood-2022-169514
https://doi.org/10.1182/blood-2022-169514
Autor:
Ellie Ivanova, Cosmin A Tegla, Ekaterina Novikova, Alberto M Herrera, Briana Mullins, Jo-Ann Latkowski, Kenneth B. Hymes, Joyoti Dey, Bin Yang, Ashwin Gollerkeri, Jared Gollob, Sergei B. Koralov
Publikováno v:
Blood. 140:3557-3558
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee941984dc6dfbfe494da74dc3ca7c98
https://doi.org/10.1182/blood-2022-156816
https://doi.org/10.1182/blood-2022-156816
Autor:
Jennifer Kimberly Lue, Don A. Stevens, Michael E. Williams, Jason Westin, Reggie Ewesuedo, Alice McDonald, Sagar Agarwal, Patrick Henrick, Rachelle Perea, Jared Gollob
Publikováno v:
Blood. 140:12143-12144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1daa5af2848bcefe4dafa5d41fa8be6a
https://doi.org/10.1182/blood-2022-170151
https://doi.org/10.1182/blood-2022-170151
Autor:
Christoph J Niemietz, Vanessa Sauer, Jacqueline Stella, Lutz Fleischhauer, Gursimran Chandhok, Sarah Guttmann, Yesim Avsar, Shuling Guo, Elizabeth J Ackermann, Jared Gollob, Brett P Monia, Andree Zibert, Hartmut H-J Schmidt
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161455 (2016)
Familial amyloid polyneuropathy (FAP) is caused by mutations of the transthyretin (TTR) gene, predominantly expressed in the liver. Two compounds that knockdown TTR, comprising a small interfering RNA (siRNA; ALN-TTR-02) and an antisense oligonucleot
Externí odkaz:
https://doaj.org/article/1796834c54db428483d9067e5e8d8e11
Autor:
Jared Gollob, John Vest, Mathew S. Maurer, Christine Powell, Verena Karsten, Thibaud Damy, Ola Akinboboye, Alberta L. Warner, Herman A. Taylor, Keyur B. Shah
Publikováno v:
Amyloid. 27:223-230
Hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) is a multisystem disease that presents with polyneuropathy and/or cardiomyopathy. DISCOVERY, a multicenter screening study, enrolled patients with clinically suspected cardiac amyloido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a83c3e1c3bc04adbef85c7b3f21f04
https://doi.org/10.1080/13506129.2020.1764928
https://doi.org/10.1080/13506129.2020.1764928
Autor:
Sonalee Agarwal, William Irish, Saša A. Živković, Danielle Brandman, Jared Gollob, Larry Gache, Hollis Lin, Anastasia McManus
Publikováno v:
Progress in Transplantation. 29:213-219
Introduction: Orthotopic liver transplantation has been used as a treatment for hereditary transthyretin-mediated (hATTR) amyloidosis, a rare, progressive, and multisystem disease. Research Question: The objective is to evaluate survival outcomes pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba9f69d7bbbc5e8ca9bda2ef69e54eb
https://doi.org/10.1177/1526924819853832
https://doi.org/10.1177/1526924819853832