Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jara J. Joedicke"'
Autor:
Jara J. Joedicke, Ulrich Großkinsky, Kerstin Gerlach, Annette Künkele, Uta E. Höpken, Armin Rehm
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 181-198 (2022)
The advent of CAR T cells targeting CD19 or BCMA on B cell neoplasm demonstrated remarkable efficacy, but rapid relapses and primary refractoriness remains challenging. A leading cause of CAR T cell failure is their lack of expansion and limited pers
Externí odkaz:
https://doaj.org/article/8e9ad936d0d54e4e84ce45152511eebf
Autor:
Mario Bunse, Janina Pfeilschifter, Julia Bluhm, Maria Zschummel, Jara J. Joedicke, Anthea Wirges, Helen Stark, Vivien Kretschmer, Markus Chmielewski, Wolfgang Uckert, Hinrich Abken, Jörg Westermann, Armin Rehm, Uta E. Höpken
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
CAR-T cell therapy targeting CD19 is not as efficient to treat lymphoma with nodal dissemination as it is for B cell leukaemia. Here, the authors generate CAR-T cells against CXCR5 and show they inhibit tumour growth by depleting both B and follicula
Externí odkaz:
https://doaj.org/article/ec898a29a91e4a4fa35537b32be47016
Autor:
Avinoam Reichman, Alexander Kunz, Jara J. Joedicke, Uta E. Höpken, Anna Keib, Brigitte Neuber, David Sedloev, Lei Wang, Genqiao Jiang, Angela Hückelhoven-Krauss, Franziska Eberhardt, Carsten Müller-Tidow, Martin Wermke, Armin Rehm, Michael Schmitt, Anita Schmitt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 903 (2022)
Chimeric-antigen-receptor (CAR)-T-cell therapy is already widely used to treat patients who are relapsed or refractory to chemotherapy, antibodies, or stem-cell transplantation. Multiple myeloma still constitutes an incurable disease. CAR-T-cell ther
Externí odkaz:
https://doaj.org/article/3db2c18fb74e4b93a9d4bd720be7894e
Autor:
Anthea Wirges, Mario Bunse, Jara J. Joedicke, Eric Blanc, Venugopal Gudipati, Michael W. Moles, Hiroshi Shiku, Dieter Beule, Johannes B. Huppa, Uta E. Höpken, Armin Rehm
Publikováno v:
Molecular Therapy. 30:3358-3378
Chimeric antigen receptor (CAR) T cells have revolutionized treatment of B cell malignancies. However, enhancing the efficacy of engineered T cells without compromising their safety is warranted. The estrogen receptor-binding fragment-associated anti
Autor:
Anthea Wirges, Armin Rehm, Mario Bunse, Jara J Joedicke, Eric Blanc, Venugopal Gudipati, Michael Moles, Dieter Beule, Johannes Huppa, Uta Hoepken
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Tessa Skroblyn, Jara J Joedicke, Madlen Pfau, Kerstin Krüger, Jean‐Pierre Bourquin, Shai Izraeli, Cornelia Eckert, Uta E Höpken
Publikováno v:
The Journal of pathologyReferences. 258(1)
The testis is the second most frequent extramedullary site of relapse in pediatric acute lymphoblastic leukemia (ALL). The mechanism for B-cell (B) ALL cell migration towards and survival within the testis remains elusive. Here, we identified CXCL12-
Autor:
Avinoam Reichman, Alexander Kunz, Jara J. Joedicke, Uta E. Höpken, Anna Keib, Brigitte Neuber, David Sedloev, Lei Wang, Genqiao Jiang, Angela Hückelhoven-Krauss, Franziska Eberhardt, Carsten Müller-Tidow, Martin Wermke, Armin Rehm, Michael Schmitt, Anita Schmitt
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 903
International Journal of Molecular Sciences, Vol 23, Iss 903, p 903 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 903
International Journal of Molecular Sciences, Vol 23, Iss 903, p 903 (2022)
Chimeric-antigen-receptor (CAR)-T-cell therapy is already widely used to treat patients who are relapsed or refractory to chemotherapy, antibodies, or stem-cell transplantation. Multiple myeloma still constitutes an incurable disease. CAR-T-cell ther
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Formation of immunological synapses between dendritic cells (DC) and conventional CD4+ T cells (Tcon) is critical for productive immune responses. However, when DCs are HIV-infected such synapses are critical to establish HIV infection. As regulatory
Externí odkaz:
https://doaj.org/article/37dca4bf523e4939beac9b15a8ce6417
Autor:
Jelka Pohar, Takahiro Adachi, Simon Fillatreau, Alex F. de Vos, Pierre Boudinot, Anna Welle, Sarantis Korniotis, Gunnar Loh, Stefan H. E. Kaufmann, Ursula Zimber-Strobl, Vinciane Flühler, Christian Goosmann, Quentin Simon, Claude-Agne` s Reynaud, Luc Jouneau, Van Duc Dang, Jara J. Joedicke, Andreas Hutloff, Jessie Thalmensi, Andreia C. Lino, Takeshi Tsubata, Imme Sakwa, Aurelia Baures, Stefanie Ries, Ulrik Stervbo, Vicky Lampropoulou, Jean-Claude Weill, Jörn Walter, Thomas Dörner, Katja Dahlke
Publikováno v:
Immunity 1 (49), 120-+. (2018)
Immunity
Immunity, 49(1), 120-133.e9. Cell Press
Immunity, Elsevier, 2018, 49 (1), pp.120-+. ⟨10.1016/j.immuni.2018.06.007⟩
Immunity, 2018, 49 (1), pp.120-+. ⟨10.1016/j.immuni.2018.06.007⟩
Immunity 49, 120-133.e9 (2018)
Immunity
Immunity, 49(1), 120-133.e9. Cell Press
Immunity, Elsevier, 2018, 49 (1), pp.120-+. ⟨10.1016/j.immuni.2018.06.007⟩
Immunity, 2018, 49 (1), pp.120-+. ⟨10.1016/j.immuni.2018.06.007⟩
Immunity 49, 120-133.e9 (2018)
Summary B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious, autoimmune, and malignant diseases. Here, we have identified a natural plasma cell subset that distinctively expresses the inhibitory receptor LAG-3 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4189f60e46cf0f47dbe490ba6e252140
http://prodinra.inra.fr/record/447645
http://prodinra.inra.fr/record/447645
Autor:
Philipp A. Lang, Jara J. Joedicke, Ulf Dittmer, Aaron B. Carmody, Tak W. Mak, Kim J. Hasenkrug, Ronald J. Messer, Lara Myers, Harald Wajant, Karl S. Lang
Publikováno v:
The Journal of Immunology. 193:2952-2960
Vβ5+ regulatory T cells (Tregs), which are specific for a mouse endogenous retroviral superantigen, become activated and proliferate in response to Friend virus (FV) infection. We previously reported that FV-induced expansion of this Treg subset was