Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jara Bouma"'
Autor:
Xiaoting Li, Hao Chang, Jara Bouma, Laura V. de Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J. B. H. N. van den Berg, Antonius P. A. Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H. Heitman, Tian Hua
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Cannabinoid CB2 receptor (CB2R) agonists are investigated as therapeutic agents in the clinic. Here, authors report the discovery of LEI-102, a CB2R agonist, used in conjunction with three other CBR ligands (APD371, HU308, and CP55,940) to investigat
Externí odkaz:
https://doaj.org/article/4a0327fb90ed454caed0f1b796b69018
Autor:
Jara, Bouma, Marjolein, Soethoudt, Noortje, van Gils, Lizi, Xia, Mario, van der Stelt, Laura H, Heitman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2576:189-199
Cannabinoid receptor 1 (CB1R) and cannabinoid receptor 2 (CB2R) are G protein-coupled receptors (GPCRs) that activate a variety of pathways upon activation by (partial) agonists including the G protein pathway and the recruitment of β-arrestins. Dif