Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Jar-Chi Lee"'
Autor:
Richard A Rudick, M R Sandhya Rani, Yaomin Xu, Jar-Chi Lee, Jie Na, Jennifer Shrock, Anupama Josyula, Elizabeth Fisher, Richard M Ransohoff
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19262 (2011)
Interferon-beta (IFNβ) is used to inhibit disease activity in multiple sclerosis (MS), but its mechanisms of action are incompletely understood, individual treatment response varies, and biological markers predicting response to treatment have yet t
Externí odkaz:
https://doaj.org/article/29442b8f56bc4023ac6d8b443d0f15ed
Autor:
Joel Moss, Kevin McCarthy, Hye-Seung Lee, Jay H. Ryu, Nishant Gupta, Nilo A. Avila, Geraldine A. Finlay, Kevin K. Brown, Stephen J. Ruoss, Angelo M. Taveira-DaSilva, Gerald J. Beck, Jar-Chi Lee, Francis X. McCormack
Publikováno v:
Chest. 155:288-296
Background The natural history of lymphangioleiomyomatosis (LAM) is mainly derived from retrospective cohort analyses, and it remains incompletely understood. A National Institutes of Health LAM Registry was established to define the natural history
Publikováno v:
Journal of Neuroimaging. 28:191-198
Background and purpose Magnetization transfer ratio (MTR), a magnetic resonance imaging technique used to assess tissue integrity, correlates with demyelination and axonal loss in multiple sclerosis (MS) lesions. In acute white matter lesions, short-
Autor:
Nobuhiko Ohno, Pauline M. Wu, Ryo Yamasaki, Lindsey Uehlein, Oleg Butovsky, Israel F. Charo, Weiwei Hu, Jessica Lin, Min Zhu, Jinyu Gu, LiPing Liu, Howard L. Weiner, Debra Dixon, Grahame J. Kidd, Nathan Sun, Jar Chi Lee, Anne C. Cotleur, Ron Cialic, Musab M. Zorlu, Anna Rietsch, Haiyan Lu, Richard M. Ransohoff, Sarah E. Taylor, Crina M. Floruta, Camille Doykan
Publikováno v:
The Journal of Experimental Medicine
Phagocytic monocyte-derived macrophages associate with the nodes of Ranvier and initiate demyelination while microglia clear debris and display a suppressed metabolic gene signature in EAE.
In the human disorder multiple sclerosis (MS) and in th
In the human disorder multiple sclerosis (MS) and in th
Publikováno v:
Multiple Sclerosis and Related Disorders. 3:473-481
Background Cognitive impairment occurs in 40–65% of patients with multiple sclerosis (MS). Less is known about the rate and pattern of cognitive decline over the course of the illness. Objective To examine long-term changes in cognition among patie
Autor:
Maria Stadtler, Ashish Atreja, Richard A. Rudick, Welf Saupe, Jar Chi Lee, Robert J. Fox, Deborah M. Miller, C. M. Harris, Shirley M. Moore, Swati Chakraborty, Alex Z. Fu
Publikováno v:
Telemedicine and e-Health. 17:5-13
No studies have addressed the use of electronic personal health records (e-PHRs) for self-management in complex neurological disorders. We assessed and tested an Internet-based self-management system that utilized the e-PHR and determined its impact
Autor:
Swathi Chakraborthy, Anupama Josyula, Jennifer Shrock, Yaomin Xu, Richard M. Ransohoff, Jar Chi Lee, M.R. Sandhya Rani, Joerg Schlaak, Richard A. Rudick, Nie Ja
Publikováno v:
Annals of the New York Academy of Sciences. 1182:58-68
Interferons (IFNs) are widely used in therapy for viral, neoplastic, and inflammatory disorders, but clinical response varies among patients. The biological basis for variable clinical response is not known. We determined the primary molecular respon
Autor:
Petra Duda, Jurgensen S, Susan Goelz, Bhupendra Khatri, Robert J. Fox, SM Man, Richard M. Ransohoff, AP Koo, F Lynn, Barbara Tucky, James Woodworth, Michael Panzara, Gavin Giovannoni, Jar-Chi Lee
Publikováno v:
Neurology. 72:402-409
Accelerating the clearance of therapeutic monoclonal antibodies (mAbs) from the body may be useful to address uncommon but serious complications from treatment, such as progressive multifocal leukoencephalopathy (PML). Treatment of PML requires immun
Publikováno v:
Annals of Neurology. 64:255-265
Objective To determine gray matter (GM) atrophy rates in multiple sclerosis (MS) patients at all stages of disease, and to identify predictors and clinical correlates of GM atrophy. Methods MS patients and healthy control subjects were observed over
Autor:
Eric Olson, Joel Moss, Jeffrey T. Chapman, Susan Sherer, Gerald J. Beck, Jay H. Ryu, Kevin K. Brown, June L. McMahan, Stephen J. Ruoss, Geraldine A. Finlay, Jar Chi Lee, Janet R. Maurer
Publikováno v:
The Journal of Heart and Lung Transplantation. 26:1293-1299
Background In 1997, the National Heart, Lung, and Blood Institute of the National Institutes of Health established a Registry to better characterize the demographic, clinical, physiologic and radiographic features of patients with lymphangioleiomyoma