Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jaqueline A. Picache"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tay-Sachs disease (TSD) is an autosomal recessive disease that features progressive neurodegenerative presentations. It affects one in 100,000 live births. Currently, there is no approved therapy or cure. This review summarizes multiple drug developm
Externí odkaz:
https://doaj.org/article/3635182fa85b4adfa256c46abccea0e5
Publikováno v:
ACS Omega, Vol 5, Iss 2, Pp 980-985 (2020)
Externí odkaz:
https://doaj.org/article/094cd45453684b80acb2081468a7c570
Autor:
Raphael Cohn, Natalie Kolba, Jaqueline A. Picache, Nancy Lin, Aisha Saleem, Wesley B. Grueber
Neurons show remarkable morphological diversity facilitated by transcriptional regulation during development and fitting with their connectivity and function. Second messenger pathways mediated by cyclic 3’,5’ adenosine or guanosine monophosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45a17769286f868dc8241896cfb7aa55
https://doi.org/10.1101/2023.04.14.536921
https://doi.org/10.1101/2023.04.14.536921
Autor:
Wenping Li, Melissa R. Pergande, Christopher A. Crutchfield, Brian C. Searle, Peter S. Backlund, Jaqueline A. Picache, Kathryn Burkert, Nicole M. Yanjanin‐Farhat, Paul S. Blank, Cynthia L. Toth, Christopher A. Wassif, Forbes D. Porter, Stephanie M. Cologna
Publikováno v:
PROTEOMICS. 23
Publikováno v:
Bioinformatics
Motivation Mass spectrometry-based untargeted lipidomics aims to globally characterize the lipids and lipid-like molecules in biological systems. Ion mobility increases coverage and confidence by offering an additional dimension of separation and a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4ea9c41797a7892f371f651a142ca2
https://europepmc.org/articles/PMC9306740/
https://europepmc.org/articles/PMC9306740/
Publikováno v:
Analytical Chemistry. 92:10759-10767
This work presents a machine learning algorithm referred to as the supervised inference of feature taxonomy from ensemble randomization (SIFTER), which supports the identification of features derived from untargeted ion mobility-mass spectrometry (IM
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 2, Pp 980-985 (2020)
ACS Omega, Vol 5, Iss 2, Pp 980-985 (2020)
Mass spectrometry (MS) is used in multiple omics disciplines to generate large collections of data. This data enables advancements in biomedical research by providing global profiles of a given system. One of the main barriers to generating these pro
Autor:
Caleb B. Morris, Jody C. May, Bailey S. Rose, James N. Dodds, John A. McLean, Jaqueline A. Picache, Charles M. Nichols, Simona G. Codreanu, Stacy D. Sherrod
Publikováno v:
Analytical Chemistry. 90:14484-14492
In this work we have established a collision cross section (CCS) library of primary metabolites based on analytical standards in the Mass Spectrometry Metabolite Library of Standards (MSMLS) using a commercially available ion mobility-mass spectromet
Autor:
Katrina L. Leaptrot, John A. McLean, Jaqueline A. Picache, Andrzej Balinski, Bailey S. Rose, Stacy D. Sherrod, Jody C. May
Publikováno v:
Chemical Science
The Unified Compendium is an online interactive tool that utilizes ion mobility collision cross sections to annotate biochemical molecules.
Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic workflows by p
Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic workflows by p
Autor:
Jody C. May, Ian D. Tomlinson, Berkley M. Ellis, David M. Hercules, John A. McLean, Rachel A. Harris, Jaqueline A. Picache, Emanuel Zlibut
Publikováno v:
Rapid Communications in Mass Spectrometry. 34
RATIONALE Commercial-grade polymer synthesis is performed via melt polymerization, which leads to polydispersion. The work reported herein provides a synthetic strategy to produce mono-dispersive polyurethane oligomers and an analytical strategy to d