Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Janyne Johnson"'
Autor:
Scott A. Campbell, Dominic P. Golec, Matt Hubert, Janyne Johnson, Nicole Salamon, Amy Barr, Patrick E. MacDonald, Koenraad Philippaert, Peter E. Light
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objectives: Our study shows that glucagon-like peptide-1 (GLP-1) is secreted within human islets and may play an unexpectedly important paracrine role in islet physiology and pathophysiology. It is known that α cells within rodent and human pancreat
Externí odkaz:
https://doaj.org/article/321056be002342d08388d9b3fb834112
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a1aee55bc1498fdfcce650424dc191
https://doi.org/10.1096/fasebj.2021.35.s1.04148
https://doi.org/10.1096/fasebj.2021.35.s1.04148
Publikováno v:
Channels
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Vitamin D is known to elicit many biological effects in diverse tissue types and is thought to act almost exclusively upon its canonical receptor within the nucleus, leading to gene transcriptional changes and the subsequent cellular response. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8fdb557bf086f3d2a3937be8fca5e5
https://pubmed.ncbi.nlm.nih.gov/33825665
https://pubmed.ncbi.nlm.nih.gov/33825665
Publikováno v:
Islets
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Glucagon-Like Peptide-1 (GLP-1) is an important peptide hormone secreted by L-cells in the gastrointestinal tract in response to nutrients. It is produced by the differential cleavage of the proglucagon peptide. GLP-1 elicits a wide variety of physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4de93e22e2a4fb0000552307367a986
https://pubmed.ncbi.nlm.nih.gov/33724156
https://pubmed.ncbi.nlm.nih.gov/33724156
Autor:
Xiao-Qing Dai, Joan Camunas-Soler, Linford J.B. Briant, Theodore dos Santos, Aliya F. Spigelman, Emily M. Walker, Rafael Arrojo e Drigo, Austin Bautista, Robert C. Jones, Dana Avrahami, James Lyon, Aifang Nie, Nancy Smith, Yongneng Zhang, Janyne Johnson, Jocelyn E. Manning Fox, Evangelos D. Michelakis, Peter E. Light, Klaus H. Kaestner, Seung K. Kim, Patrik Rorsman, Roland W. Stein, Stephen R. Quake, Patrick E. MacDonald
Publikováno v:
Cell Metabolism. 34:256-268.e5
In diabetes, glucagon secretion from pancreatic α cells is dysregulated. The underlying mechanisms, and whether dysfunction occurs uniformly among cells, remain unclear. We examined α cells from human donors and mice using electrophysiological, tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eac90d7171781caea40308d96aa4b3
https://doi.org/10.1016/j.cmet.2021.12.021
https://doi.org/10.1016/j.cmet.2021.12.021
Publikováno v:
OBM Transplantation. 3:1-1
Background One of the goals of clinical islet transplantation is to achieve a single-donor transplant that is dependent on obtaining enough quality cell mass from one donor pancreas. Human islets are routinely cultured prior to transplantation, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24513decbfffbd01294ae9b4dfff951d
https://doi.org/10.21926/obm.transplant.1902069
https://doi.org/10.21926/obm.transplant.1902069