Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Janusz Witowski"'
Autor:
Edyta Kawka, Rebecca Herzog, Marcin Ruciński, Agnieszka Malińska, Markus Unterwurzacher, Juan Manuel Sacnun, Anja Wagner, Katarzyna Kowalska, Karol Jopek, Agata Kucz-Chrostowska, Klaus Kratochwill, Janusz Witowski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Transforming growth factor β (TGF-β) is implicated in both mesothelial-to-mesenchymal transition (MMT) and cellular senescence of human peritoneal mesothelial cells (HPMCs). We previously showed that senescent HPMCs could spontaneously acq
Externí odkaz:
https://doaj.org/article/2cb8718db5424f74bfee025654002816
Autor:
Michael Adu-Gyamfi, Claudia Goettsch, Julian Kamhieh-Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunssen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, Henning Morawietz, Janusz Witowski, Rusan Catar
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 500 (2024)
Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechani
Externí odkaz:
https://doaj.org/article/93e54855a4cf439a8fdd4396e9578845
Autor:
Guido Moll, Christian Luecht, Michael Adu Gyamfi, Dennyson L. M. da Fonseca, Pinchao Wang, Hongfan Zhao, Zexian Gong, Lei Chen, Muhamad Imtiaz Ashraf, Harald Heidecke, Alexander Maximilian Hackel, Duska Dragun, Klemens Budde, Olaf Penack, Gabriela Riemekasten, Otávio Cabral-Marques, Janusz Witowski, Rusan Catar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Non-HLA-directed regulatory autoantibodies (RABs) are known to target G-protein coupled receptors (GPCRs) and thereby contribute to kidney transplant vasculopathy and failure. However, the detailed underlying signaling mechanisms in human microvascul
Externí odkaz:
https://doaj.org/article/0550d2a8fe9d406f9dee0534c4a001b2
Autor:
Hongfan Zhao, Dashan Wu, Michael Adu Gyamfi, Pinchao Wang, Christian Luecht, Anna Maria Pfefferkorn, Muhammad Imtiaz Ashraf, Julian Kamhieh-Milz, Janusz Witowski, Duska Dragun, Klemens Budde, Ralf Schindler, Daniel Zickler, Guido Moll, Rusan Catar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
AimsExpanded hemodialysis (HDx) therapy with improved molecular cut-off dialyzers exerts beneficial effects on lowering uremia-associated chronic systemic microinflammation, a driver of endothelial dysfunction and cardiovascular disease (CVD) in hemo
Externí odkaz:
https://doaj.org/article/eb3a57d09178403b87ad5ee78122776d
Autor:
Kacper Nijakowski, Rafał Rutkowski, Dawid Gruszczyński, Janusz Witowski, Anna Surdacka, Dominika Kanikowska
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 10 (2024)
Background: The interaction between oxidative status markers and biological rhythms is considered particularly important in the pathogenesis of many diseases and more effective therapies. We aimed to determine if the salivary secretion of myeloperoxi
Externí odkaz:
https://doaj.org/article/a316a251809f468f962ca04edc8eb1b2
Autor:
Martyna Marciniak, Maki Sato, Rafał Rutkowski, Agnieszka Zawada, Aldona Juchacz, Dagmara Mahadea, Marian Grzymisławski, Agnieszka Dobrowolska, Edyta Kawka, Katarzyna Korybalska, Andrzej Bręborowicz, Janusz Witowski, Dominika Kanikowska
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionPhysiological and biochemical processes in the human body occur in a specific order and show rhythmic variability. Time dependence characterizes the secretion of cortisol and dehydroepiandrosterone (DHEA). One-day fasting implies alternat
Externí odkaz:
https://doaj.org/article/0995fe3d389e4b1284667c2b8cfc13a0
Autor:
Kacper Nijakowski, Anna Lehmann, Rafał Rutkowski, Katarzyna Korybalska, Janusz Witowski, Anna Surdacka
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 8, p 168 (2023)
Background: Increased myeloperoxidase (MPO) levels in saliva are thought to reflect ongoing periodontal inflammation. Less clear is whether and to what extent salivary MPO is increased as a result of systemic inflammation. Methods: In the present stu
Externí odkaz:
https://doaj.org/article/0399302aec0a40199506714f621a7eb9
Autor:
Rusan Ali Catar, Maria Bartosova, Edyta Kawka, Lei Chen, Iva Marinovic, Conghui Zhang, Hongfan Zhao, Dashan Wu, Daniel Zickler, Honorata Stadnik, Marek Karczewski, Julian Kamhieh-Milz, Achim Jörres, Guido Moll, Claus Peter Schmitt, Janusz Witowski
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Peritoneal dialysis (PD) is a valuable ‘home treatment’ option, even more so during the ongoing Coronavirus pandemic. However, the long-term use of PD is limited by unfavourable tissue remodelling in the peritoneal membrane, which is associated w
Externí odkaz:
https://doaj.org/article/5d5b9dd4d4a64992aac0d24af8da1854
Autor:
Rusan Catar, Guido Moll, Julian Kamhieh-Milz, Christian Luecht, Lei Chen, Hongfan Zhao, Lucas Ernst, Kevin Willy, Matthias Girndt, Roman Fiedler, Janusz Witowski, Henning Morawietz, Olle Ringdén, Duska Dragun, Kai-Uwe Eckardt, Ralf Schindler, Daniel Zickler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
AbstractSystemic chronic microinflammation and altered cytokine signaling, with adjunct cardiovascular disease (CVD), endothelial maladaptation and dysfunction is common in dialysis patients suffering from end-stage renal disease and associated with
Externí odkaz:
https://doaj.org/article/2b5da9f8659e4b1c889dc9aee829ea9d
Autor:
Dominika Kanikowska, Alina Kanikowska, Rafał Rutkowski, Małgorzata Włochal, Zofia Orzechowska, Aldona Juchacz, Agnieszka Zawada, Marian Grzymisławski, Magdalena Roszak, Maki Sato, Andrzej Bręborowicz, Janusz Witowski
Publikováno v:
Pharmaceutical Biology, Vol 57, Iss 1, Pp 140-144 (2019)
Context: Amaranth and canola oils have been used traditionally. Amaranth has been identified as being of interest because of its outstanding nutritive value. Amaranth oil is a rich source of highly unsaturated fats and so could be a valuable dietary
Externí odkaz:
https://doaj.org/article/c1bb97e435ed408f9cee5b1cd4cd3493