Výsledky vyhledávání - "Janusz Sokolowski"

Akademický článek

Antiplatelet therapy prior to COVID-19 infection impacts on patients mortality: a propensity score-matched cohort study

Autor: Mateusz Sokolski, Konrad Reszka, Barbara Adamik, Katarzyna Kilis-Pstrusinska, Weronika Lis, Michał Pomorski, Janusz Sokolowski, Adrian Doroszko, Katarzyna Madziarska, Ewa Anita Jankowska, Marcin Protasiewicz

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Abstract One of the major pathomechanisms of COVID-19 is the interplay of hyperinflammation and disruptions in coagulation processes, involving thrombocytes. Antiplatelet therapy (AP) by anti-inflammatory effect and inhibition of platelet aggregation

Externí odkaz: https://doaj.org/article/8fbabbd4f10541dbb8ccaa3f16b1c4e2

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Akademický článek

Usefulness of the CHA2DS2-VASc Score in Predicting the Outcome in Subjects Hospitalized with COVID-19—A Subanalysis of the COLOS Study

Autor: Katarzyna Resler, Pawel Lubieniecki, Tomasz Zatonski, Adrian Doroszko, Malgorzata Trocha, Marek Skarupski, Krzysztof Kujawa, Maciej Rabczynski, Edwin Kuznik, Dorota Bednarska-Chabowska, Marcin Madziarski, Tymoteusz Trocha, Janusz Sokolowski, Ewa A. Jankowska, Katarzyna Madziarska

Publikováno v: Microorganisms, Vol 12, Iss 10, p 2060 (2024)

Background: The aim of this study was to see if the CHA2DS2-VASc score (Cardiac failure or dysfunction, Hypertension, Age ≥ 75 [Doubled], Diabetes, Stroke [Doubled]—Vascular disease, Age 65–74 and Sex category [Female] score) could have potenti

Externí odkaz: https://doaj.org/article/2d6863e43c7743bd9ff9e165c18c7738

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Akademický článek

Pre-hospital oxygen therapy and saturation variability in COVID-19 patients with and without glucose metabolism disorders: part of the COLOS Study

Autor: Agnieszka Bronowicka-Szydełko, Łukasz Lewandowski, Pawel Lubieniecki, Joanna Adamiec-Mroczek, Adrian Doroszko, Małgorzata Trocha, Krzysztof Kujawa, Agnieszka Matera-Witkiewicz, Maciej Rabczyński, Edwin Kuźnik, Marcin Madziarski, Janusz Sokołowski, Ewa A. Jankowska, Katarzyna Madziarska

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

Abstract The COVID-19 pandemic has revealed that viruses can have multiple receptor properties, penetrating various tissues and causing mutations in various genes, thus promoting a range of metabolic disorders. The purpose of this study was to invest

Externí odkaz: https://doaj.org/article/baf9b1f080c84af08be1526d72b12113

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History of Heart Failure in Patients Hospitalized Due to COVID-19: Relevant Factor of In-Hospital Complications and All-Cause Mortality up to Six Months

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 241
Journal of Clinical Medicine, Vol 11, Iss 241, p 241 (2022)
Journal of Clinical Medicine

Background: Patients with heart failure (HF) are at high risk of unfavorable courses of COVID-19. The aim of this study was to evaluate characteristics and outcomes of COVID-19 patients with HF. Methods: Data of patients hospitalized in a tertiary ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288fcbd1aa653ae496b40e3f735c7a18

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Akademický článek

The Usefulness of the C2HEST Score in Predicting the Clinical Outcomes of COVID-19 in COPD and Non-COPD Cohorts

Autor: Jakub Gawryś, Adrian Doroszko, Olgierd Dróżdż, Małgorzata Trocha, Damian Gajecki, Karolina Gawryś, Ewa Szahidewicz-Krupska, Maciej Rabczyński, Krzysztof Kujawa, Piotr Rola, Agata Stanek, Janusz Sokołowski, Marcin Madziarski, Ewa Anita Jankowska, Agnieszka Bronowicka-Szydełko, Dorota Bednarska-Chabowska, Edwin Kuźnik, Katarzyna Madziarska

Publikováno v: Microorganisms, Vol 12, Iss 6, p 1238 (2024)

Patients with chronic obstructive pulmonary disease (COPD) infected with SARS-CoV-2 indicate a higher risk of severe COVID-19 course, which is defined as the need for hospitalization in the intensive care unit, mechanical ventilation, or death. Howev

Externí odkaz: https://doaj.org/article/44e82d2ede624feaa81b01ce75e30f8e

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Akademický článek

Insulin and Metformin Administration: Unravelling the Multifaceted Association with Mortality across Various Clinical Settings Considering Type 2 Diabetes Mellitus and COVID-19

Autor: Łukasz Lewandowski, Agnieszka Bronowicka-Szydełko, Maciej Rabczyński, Dorota Bednarska-Chabowska, Joanna Adamiec-Mroczek, Adrian Doroszko, Małgorzata Trocha, Krzysztof Kujawa, Agnieszka Matera-Witkiewicz, Edwin Kuźnik, Paweł Lubieniecki, Marcin Madziarski, Janusz Sokołowski, Ewa A. Jankowska, Katarzyna Madziarska

Publikováno v: Biomedicines, Vol 12, Iss 3, p 605 (2024)

Due to the molecular mechanisms of action of antidiabetic drugs, they are considered to be effective in the treatment of both COVID-19 and the post-COVID-19 syndromes. The aim of this study was to determine the effect of administering insulin and met

Externí odkaz: https://doaj.org/article/1417b3d365274c64ba377da31837b5b9

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Akademický článek

Association of serum vitamin D concentration with the final course of hospitalization in patients with COVID-19

Autor: Klaudia Konikowska, Katarzyna Kiliś-Pstrusińska, Agnieszka Matera-Witkiewicz, Krzysztof Kujawa, Barbara Adamik, Adrian Doroszko, Krzysztof Kaliszewski, Michał Pomorski, Marcin Protasiewicz, Janusz Sokołowski, Katarzyna Madziarska, Ewa Anita Jankowska

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundVitamin D deficiency is a substantial public health problem. The present study evaluated the association between vitamin D concentration and hospitalization and mortality risk in patients with coronavirus disease 19 (COVID-19).MethodsThis s

Externí odkaz: https://doaj.org/article/5211183ecdcd436f8a6ba78c348df2fb

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Cyclization ofN(Tetra-O-acetyl-d-gluco- andd-Mannopyranosyl)-Pyridinium Salts in a Methanolic Solution of Sodium Methylate

Autor: Andrzej Wiśniewski, Eugenia Skorupowa, Barbara Dmochowska, F. Kasprzykowski, J. Madaj, Janusz Sokolowski

Publikováno v: Journal of Carbohydrate Chemistry. 17:49-59

N-(2,3,4,6-Tetra-O-acetyl-α-d-gluco-, β-d-gluco- and β-d-mannopyranosyl)-pyridinium salts were obtained and their structures were determined by 2D 1H NMR spectroscopy. The compounds obtained were treated with a methanolic solution of sodium methyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::accc32dcd1ce76a97e04f3466cac337a
https://doi.org/10.1080/07328309808005768

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CGC, MS and theoretical studies on the transformation mechanism of 3,4-di-O-acetyl-1,5-anhydro-2-deoxy-D-threo-pent-1-enitol in aqueous solutions

Autor: Janusz Rak, Janusz Madaj, Eugenia Skorupowa, Janusz Sokolowski, Anna Łopacińska, Andrzej Wiśniewski

Publikováno v: Scopus-Elsevier

Heating 3,4-di-O-acetyl-1,5-anhydro-2-deoxy-D-threo-pent-1-enitol (per-O-acetyl-D-xylal) in water leads to a mixture of unsaturated compounds with cyclic, as well as open-chain structures. The mixture obtained was analysed by CGC and CGC–MS methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9984dec83003647b27c6cf48f36283c2
https://doi.org/10.1039/p29950000569

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1,6-Cyclization Reactions of Selected AldohexopyranosesviaTheir 1-O-Tosyl Derivatives

Autor: Andrzej Wiśniewski, Eugenia Skorupowa, Janusz Sokolowski, Janusz Madaj

Publikováno v: Journal of Carbohydrate Chemistry. 13:873-880

2,3,4,6-Tetra-O-acetyl-d-gluco-, d-galacto- and d-mannopyranoses were tosylated with p-tolenesulfonyl chloride to afford their 1-O-tosyl derivatives which were cyclized “in situ” in a methanolic solution of sodium methoxide. 1,6-Cyclization produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3506679ec4a3928ed66097dfb4268854
https://doi.org/10.1080/07328309408011687

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