Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Janusz Madaj"'
Autor:
Karol Sikora, Piotr Szweda, Karolina Słoczyńska, Justyna Samaszko-Fiertek, Janusz Madaj, Beata Liberek, Elżbieta Pękala, Barbara Dmochowska
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 888 (2023)
Eight N-[2-(2′,3′,4′-tri-O-acetyl-α/β-d-xylopyranosyloxy)ethyl]ammonium bromides, a new class of d-xylopyranosides containing a quaternary ammonium aglycone, were obtained. Their complete structure was confirmed using NMR spectroscopy (1H, 13
Externí odkaz:
https://doaj.org/article/ec3acdc2a4ae457b904b410e7e6c3289
Publikováno v:
Molecules, Vol 27, Iss 3, p 787 (2022)
Schiff bases are a vast group of compounds characterized by the presence of a double bond linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to combine a variety of alkyl or aryl substituents. Compounds of this
Externí odkaz:
https://doaj.org/article/0d0534d8298d4ad086d55039aa50c300
Autor:
Barbara Dmochowska, Rafał Ślusarz, Jarosław Chojnacki, Justyna Samaszko-Fiertek, Janusz Madaj
Publikováno v:
Molecules, Vol 25, Iss 9, p 2161 (2020)
The synthesis of N-((methyl 5-deoxy-2,3-O-isopropylidene-β-D-ribofuranoside)-5-yl)ammonium salts are presented. To determine the effect of the nucleophile type and outgoing group on the quaternization reaction, selected aliphatic and heterocyclic ar
Externí odkaz:
https://doaj.org/article/289f6f948d0546309eb3d7b6caef3d03
Autor:
Barbara Dmochowska, Monika Szulc, Wojciech Kamysz, Maciej Jaśkiewicz, J. Samaszko-Fiertek, Rafał Ślusarz, Janusz Madaj
Publikováno v:
Letters in Organic Chemistry. 17:287-293
This paper presents synthesis of vancomycin derivatives modified with selected 1- and 2-aminoalditols to carboxylic function and 2,5-anhydro-D-mannose and D-talose to amino function of vancosamine via reductive alkylation. MIC and MBC of these deriva
Autor:
Justyna Samaszko-Fiertek, Barbara Dmochowska, Krzysztof Brzozowski, Janusz Madaj, Rafal Slusarz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1146, p 1146 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1146
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1146
The article describes an NMR spectroscopy study of interactions between vancomycin and a muramyl pentapeptide in two complexes: vancomycin and a native muramyl pentapeptide ended with D-alanine (MPP-D-Ala), and vancomycin and a modified muramyl penta
Efficient synthesis and antifungal investigation of nucleosides’ quaternaryammonium salt derivatives
Autor:
J. Samaszko-Fiertek, Barbara Dmochowska, Lucyna Pellowska-Januszek, Roland Wakiec, Rafal Slusarz, Janusz Madaj
Publikováno v:
TURKISH JOURNAL OF CHEMISTRY. 43:157-171
Quaternary ammonium salts are a group of compounds with diverse biological properties, the most important of which are their antiviral, antibacterial, and antifungal activities. The quaternization reactions of 5'-O-tosyl derivatives of uridine and th
Publikováno v:
Letters in Organic Chemistry. 15:693-697
Autor:
Rafał Ślusarz, J. Samaszko-Fiertek, Monika Szulc, Artur Sikorski, Kornelia Kowalska, Janusz Madaj
Publikováno v:
Journal of Carbohydrate Chemistry. 35:161-171
Solid phase peptide synthesis (SPPS) of two selected muramyl pentapeptide derivatives is described. The simplicity of removing the protecting groups via one-step deprotection and cleavage from the resin is the biggest advantage of SPPS. Using this me
Publikováno v:
Carbohydrate Research. 389:154-164
Proper understanding of the mechanisms of binding to Gram-positive bacteria cell wall layers-especially to the peptidoglycan (PG) layer, seems to be crucial for proper development of new drug candidates which are effective against these bacteria. In
Computational investigations were performed to examine the effects of the addition of 2-acetamido-2-deoxy-β-D-galactopyranosylamine or 1-amino-1-deoxy-D-glucitol connected to the C-terminus of vancomycin with different linkers. The purpose of this m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68593043800fc125557837d8061e5905