Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Janusz Kopczyński"'
Autor:
Izabela Ciepiela, Magdalena Szczepaniak, Przemysław Ciepiela, Kinga Hińcza-Nowak, Janusz Kopczyński, Paweł Macek, Kamila Kubicka, Magdalena Chrapek, Magdalena Tyka, Stanisław Góźdź, Artur Kowalik
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Despite the introduction of new molecular classifications, advanced colorectal cancer (CRC) is treated with chemotherapy supplemented with anti-EGFR and anti-VEGF targeted therapy. In this study, 552 CRC cases with different primary tumor lo
Externí odkaz:
https://doaj.org/article/04a120e8d3134eceb43e094e9497635c
Autor:
Danuta Gąsior-Perczak, Artur Kowalik, Janusz Kopczyński, Paweł Macek, Kornelia Niemyska, Agnieszka Walczyk, Krzysztof Gruszczyński, Monika Siołek, Tomasz Dróżdż, Marcin Kosowski, Iwona Pałyga, Piotr Przybycień, Olga Wabik, Stanisław Góźdź, Aldona Kowalska
Publikováno v:
Cancers, Vol 16, Iss 4, p 815 (2024)
The aim of this study was to determine whether the expression of CHK2 and p53 in tumor tissue in carriers of germline CHEK2 mutations can serve as a prognostic marker for PTC, and whether CHEK2 and TP53 copy numbers correlates with the course of PTC
Externí odkaz:
https://doaj.org/article/d55e709c11874962823c7f2715682fbb
Autor:
Kinga Hińcza-Nowak, Artur Kowalik, Agnieszka Walczyk, Iwona Pałyga, Danuta Gąsior-Perczak, Agnieszka Płusa, Janusz Kopczyński, Magdalena Chrapek, Stanisław Góźdź, Aldona Kowalska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10019 (2023)
Medullary thyroid cancer (MTC) is a rare malignancy, and the treatment of metastatic MTC is challenging. In previous work, immune profiling (RNA-Seq) of MTC identified CD276 as a potential target for immunotherapy. CD276 expression was 3-fold higher
Externí odkaz:
https://doaj.org/article/2774fef64ebe4adca2ed7aff11f0918c
Autor:
Artur Bocian, Piotr Kędzierawski, Janusz Kopczyński, Olga Wabik, Anna Wawruszak, Michał Kiełbus, Paulina Miziak, Andrzej Stepulak
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 1, p 370 (2023)
Triple-negative breast cancers (TNBCs) are histologically heterogenic invasive carcinomas of no specific type that lack distinctive histological characteristics. The prognosis for women with TNBC is poor. Regardless of the applied treatments, recurre
Externí odkaz:
https://doaj.org/article/f84286f18390455d83c36c661586f098
Autor:
Artur Kowalik, Andrzej Wincewicz, Sebastian Zięba, Wojciech Baran, Janusz Kopczyński, Mariusz Koda, Stanisław Sulkowski, Stanisław Goźdź
Publikováno v:
Polish Journal of Pathology, Vol 71, Iss 1, Pp 69-74 (2020)
Molecular next gene sequencing was used to evaluate mutations in 409 common mutated cancer-related genes in malignant mesothelioma of tunica vaginalis testis (MMTVT) of 81-year-old man. Multifocal papillary-solid areas contained necrosis among highly
Externí odkaz:
https://doaj.org/article/f782ac6467194818b1f6e7cc02bfa20c
Autor:
Tomasz Wollny, Urszula Wnorowska, Ewelina Piktel, Łukasz Suprewicz, Grzegorz Król, Katarzyna Głuszek, Stanisław Góźdź, Janusz Kopczyński, Robert Bucki
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7443 (2022)
It has been proven that tumour growth and progression are regulated by a variety of mediators released during the inflammatory process preceding the tumour appearance, but the role of inflammation in the development of bladder cancer is ambiguous. Th
Externí odkaz:
https://doaj.org/article/d3ce9a039b114c2abb0c9a8ecb1eb79f
Autor:
Artur Kowalik, Kamil Zalewski, Janusz Kopczyński, Monika Siołek, Magda Lech, Kinga Hińcza, Joanna Kalisz, Magdalena Chrapek, Sebastian Zięba, Jowita Furmańczyk, Michał Jedliński, Małgorzata Chłopek, Marcin Misiek, Stanisław Góźdź
Publikováno v:
Polish Journal of Pathology, Vol 70, Iss 2, Pp 115-126 (2019)
Ovarian cancer (OC) is the most lethal among gynecologic malignancies worldwide. Unfortunately, in around 70% of cases cancer is diagnosed in late stages (III-IV) which decreases the 5-year survival rate to 25%. The standard of care in ovarian cancer
Externí odkaz:
https://doaj.org/article/08cf8c6767af4b8c9a1bb8629b329838
Publikováno v:
Endocrine Connections, Vol 9, Iss 3, Pp R47-R58 (2020)
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a borderline thyroid tumour formerly known as noninvasive encapsulated follicular variant of papillary thyroid carcinoma. The prevalence of NIFTP is estimated at
Externí odkaz:
https://doaj.org/article/259bd50913484c0fb9645e8a346a8a7c
Autor:
Agnieszka Walczyk, Janusz Kopczyński, Danuta Gąsior-Perczak, Iwona Pałyga, Artur Kowalik, Magdalena Chrapek, Maria Hejnold, Stanisław Góźdź, Aldona Kowalska
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229264 (2020)
BACKGROUND:Poorly differentiated thyroid cancer (PDTC) is a rare but aggressive type of thyroid cancer (TC) and the main cause of death from non-anaplastic follicular cell-derived TC. Although the Turin criteria are well defined, the pathological fea
Externí odkaz:
https://doaj.org/article/7d5fe19dad954db2bcd2da7fd6c257b6
Autor:
Kinga Hińcza-Nowak, Artur Kowalik, Agnieszka Walczyk, Iwona Pałyga, Danuta Gąsior-Perczak, Agnieszka Płusa, Janusz Kopczyński, Magdalena Chrapek, Stanisław Góźdź, Aldona Kowalska
Publikováno v:
Genes, Vol 12, Iss 10, p 1534 (2021)
Medullary thyroid cancer (MTC) is a rare malignancy that arises from calcitonin-producing C-cells. Curative treatment for patients with metastatic MTC is challenging. Identifying the mechanisms by which cancer cells inhibit the activity of immune cel
Externí odkaz:
https://doaj.org/article/272dc10cb931467584d56ace55eaf11f