Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Janusz, Zabrocki"'
Autor:
Vikas Jindal, Daqi Li, Leslie C. Rault, Soheila Fatehi, Rupinder Singh, Moritz Mating, Ye Zou, Ho-Leung Ng, Krzysztof Kaczmarek, Janusz Zabrocki, Shunhua Gui, Guy Smagghe, Troy D. Anderson, Ronald J. Nachman, Yoonseong Park
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The devastating Varroa mite (Varroa destructor Anderson and Trueman) is an obligatory ectoparasite of the honey bee, contributing to significant colony losses in North America and throughout the world. The limited number of conventional acar
Externí odkaz:
https://doaj.org/article/ff46c051c6e44568a8801c5c7aa1bae0
Publikováno v:
Molecules, Vol 27, Iss 11, p 3552 (2022)
The core of Cyclolinopeptide A (CLA, cyclo(LIILVPPFF)), responsible for its high immunosuppressive activity, contains a Pro-Pro-Phe-Phe sequence. A newly synthesized cyclic tetrapeptide, cyclo(Pro-Pro-β3-HoPhe-Phe) (denoted as 4B8M) bearing the acti
Externí odkaz:
https://doaj.org/article/203bdc5400f64daea9a1c3fe29da60b7
Autor:
Krzysztof Kaczmarek, Barbara Pacholczyk-Sienicka, Łukasz Albrecht, Janusz Zabrocki, Ronald J. Nachman
Publikováno v:
Molecules, Vol 26, Iss 11, p 3271 (2021)
A facile solid-phase synthetic method for incorporating the imidazoline ring motif, a surrogate for a trans peptide bond, into bioactive peptides is reported. The example described is the synthesis of an imidazoline peptidomimetic analog of an insect
Externí odkaz:
https://doaj.org/article/a9fa48a876c849cdb59e8ba2176fec20
Autor:
Vasso Apostolopoulos, Joanna Bojarska, Tsun-Thai Chai, Sherif Elnagdy, Krzysztof Kaczmarek, John Matsoukas, Roger New, Keykavous Parang, Octavio Paredes Lopez, Hamideh Parhiz, Conrad O. Perera, Monica Pickholz, Milan Remko, Michele Saviano, Mariusz Skwarczynski, Yefeng Tang, Wojciech M. Wolf, Taku Yoshiya, Janusz Zabrocki, Piotr Zielenkiewicz, Maha AlKhazindar, Vanessa Barriga, Konstantinos Kelaidonis, Elham Mousavinezhad Sarasia, Istvan Toth
Publikováno v:
Molecules, Vol 26, Iss 2, p 430 (2021)
Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with protein-protein interactions, which are indispensable in bio-processes. Short peptides include fundament
Externí odkaz:
https://doaj.org/article/d2137ab22429462d894e99915a48f3f4
Autor:
Michał Zimecki, Jolanta Artym, Wojciech Kałas, Leon Strządała, Katarzyna Kaleta-Kuratewicz, Jan Kuryszko, Andrzej Kaszuba, Krzysztof Kaczmarek, Janusz Zabrocki
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1030 (2020)
A cyclic tetrapeptide Pro-Pro-Pheβ3ho-Phe (4B8M) was tested for immunosuppressive activity and potential therapeutic utility in several in vitro and in vivo mouse and human models. The tetrapeptide was less toxic for mouse splenocytes in comparison
Externí odkaz:
https://doaj.org/article/bcd244c131904481bce0f7c27e5622b3
Autor:
Joanna Bojarska, Milan Remko, Martin Breza, Izabela D. Madura, Krzysztof Kaczmarek, Janusz Zabrocki, Wojciech M. Wolf
Publikováno v:
Molecules, Vol 25, Iss 5, p 1135 (2020)
The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are
Externí odkaz:
https://doaj.org/article/d778c51bf54c4fe0bfa2f182f417c111
Autor:
Shun-Hua Gui, Yu-Xia Pei, Li Xu, Wei-Ping Wang, Hong-Bo Jiang, Ronald J Nachman, Krzysztof Kaczmarek, Janusz Zabrocki, Jin-Jun Wang
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193058 (2018)
Natalisins (NTLs) are conservative neuropeptides, which are only found in arthropods and are documented to regulate reproductive behaviors in insects. In our previous study, we have confirmed that NTLs regulate the reproductive process in an importan
Externí odkaz:
https://doaj.org/article/ebdb209842da4e97ab9b3c8fb7d61e66
Autor:
Guy Smagghe, Yan Shi, Janusz Zabrocki, Ronald J. Nachman, Shun-Hua Gui, Shireen A. Davies, Julian A. T. Dow, Niels Piot, Krzysztof Kaczmarek
Publikováno v:
Insect Science. 29:521-530
Insect CAPA neuropeptides are considered to affect water and ion balance by mediating the physiological metabolism activities of the Malpighian tubules. In previous studies, the CAPA-PK analogue 1895 (2Abf-Suc-FGPRLamide) was reported to decrease aph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedbc2bc5135a7078fef932ef0ed84d6
https://doi.org/10.1111/1744-7917.12951
https://doi.org/10.1111/1744-7917.12951
Autor:
Joanna Bojarska, Janusz Zabrocki, Krzysztof Kaczmarek, Andrzej Olczak, Jakub Wojciechowski, Izabela D. Madura, Wojciech M. Wolf, Milan Remko
Publikováno v:
Journal of Molecular Structure. 1190:11-22
The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon polymorphism, can be interesting inter alia from the point of view of modern supramolecular biofunctional materials. A novel crystalline phase (1) was successfully syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37629ae153da1c3ac58f8abf3cb79b30
https://doi.org/10.1016/j.molstruc.2019.04.045
https://doi.org/10.1016/j.molstruc.2019.04.045
Autor:
Caixing Xiong, Patricia V. Pietrantonio, Janusz Zabrocki, Krzysztof Kaczmarek, Ronald J. Nachman
Publikováno v:
General and Comparative Endocrinology. 278:58-67
Insect kinins modulate aspects of diuresis, digestion, development, and sugar taste perception in tarsi and labellar sensilla in mosquitoes. They are, however, subject to rapid biological degradation by endogenous invertebrate peptidases. A series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7651c858550856174519fe6e69a7abfd
https://doi.org/10.1016/j.ygcen.2018.08.002
https://doi.org/10.1016/j.ygcen.2018.08.002