TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan hydroxylase 1 concentrations in acute pancreatitis patients

Autor: Jadwiga Snarska, Ewa Fiedorowicz, Dominika Rozmus, Konrad Wroński, Maria Latacz, Natalia Kordulewska, Janusz Płomiński, Roman Grzybowski, Huub F.J. Savelkoul, Elżbieta Kostyra, Anna Cieślińska

Publikováno v: BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background The role of serotonin and its metabolic pathway in proper functioning of the pancreas has not been thoroughly investigated yet in acute pancreatitis (AP) patients. Tryptophan hydroxylase (TPH) as the rate-limiting enzyme of seroto

Externí odkaz: https://doaj.org/article/31ff4eaf50e44e12b1208130a13c5f04

Vitamin D Metabolic Pathway Components in Orthopedic Patientes-Systematic Review

Autor: Janusz Płomiński, Roman Grzybowski, Ewa Fiedorowicz, Edyta Sienkiewicz-Szłapka, Dominika Rozmus, Angelika Król-Grzymała, Beata Jarmołowska, Natalia Kordulewska, Anna Cieślińska

Publikováno v: International journal of molecular sciences. 23(24)

Vitamin D takes part in the functioning of many processes that ensure the homeostasis of the body. In orthopedics, it is indicated as an inseparable element ensuring proper bone growth and functioning, and its deficiencies are indicated in various di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32182d02b6e2dbd42b3d7277cf3e94ba
https://pubmed.ncbi.nlm.nih.gov/36555202

rs7041 and rs4588 Polymorphisms in Vitamin D Binding Protein Gene (VDBP) and the Risk of Diseases

Autor: Dominika Rozmus, Janusz Płomiński, Klaudia Augustyn, Anna Cieślińska

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 933, p 933 (2022)
International Journal of Molecular Sciences

The purpose of the study was to investigate the role of vitamin D binding protein (VDBP, DBP) and its polymorphism in the vitamin D pathway and human health. This narrative review shows the latest literature on the most popular diseases that have pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c053598a9c60eef21905d97050b9c4
https://www.mdpi.com/1422-0067/23/2/933

Vitamin D Binding Protein (VDBP) and Its Gene Polymorphisms—The Risk of Malignant Tumors and Other Diseases

Autor: Alicja Ciesielska, Janusz Płomiński, Natalia Karolina Kordulewska, Roman Grzybowski, Anna Cieślińska, Dominika Rozmus, Huub F. J. Savelkoul, Ewa Fiedorowicz, Elżbieta Kostyra

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7822, p 7822 (2020)
International Journal of Molecular Sciences, 21(21)
International Journal of Molecular Sciences 21 (2020) 21
International Journal of Molecular Sciences

Vitamin D is an important component of the endocrine system that controls calcium homeostasis and bone mineralization. Because of the very short half-life of free serum vitamin D it is stabilized and transported to target tissues by being bound to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc57b4ee2d73b51269e01b6020ecaa1
https://www.mdpi.com/1422-0067/21/21/7822

Role of rs193922155 in the etiopathogenesis of osteogenesis imperfecta with description of the phenotype

Autor: Anna Cieślińska, Roman Grzybowski, Janusz Płomiński, Ewa Fiedorowicz, Marek Szwabowicz, Maria Latacz

Publikováno v: Medicine

Introduction: Osteogenesis imperfecta (OI) is a disorder of the connective tissue that mainly causes the bones to become excessively brittle. The vast majority of OI cases are associated with mutations in the genes encoding the I alpha. Patient conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ab9c2671998e1298e37f4d4c89fbc5
https://doi.org/10.1097/md.0000000000027021