Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janus H. Magnussen"'
Autor:
Janus H. Magnussen, Anders Ettrup, Szabolcs Lehel, Dan Peters, Agnete Dyssegaard, Morten S. Thomsen, Jens D. Mikkelsen, Gitte M. Knudsen
Publikováno v:
Frontiers in Neuroimaging, Vol 3 (2024)
The alpha7 nicotinic acetylcholine receptor (α7-nAChR) has has long been considered a promising therapeutic target for addressing cognitive impairments associated with a spectrum of neurological and psychiatric disorders, including Alzheimer's disea
Externí odkaz:
https://doaj.org/article/8e3fcf4ca7914f3da7f774cded81f30c
Autor:
Lene Lundgaard Donovan, Hanne D. Hansen, Agnete Dyssegaard, Szabolcs Lehel, Gitte M. Knudsen, Janus H. Magnussen, Jacob M. Hooker
Publikováno v:
Molecular Imaging and Biology. 22:569-577
With the emerging knowledge about the impact of epigenetic alterations on behavior and brain disorders, the ability to measure epigenetic alterations in brain tissue in vivo has become critically important. We present the first in vivo/in vitro cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11de2685f6928a4aa516c59d7536bc0b
https://doi.org/10.1007/s11307-019-01403-9
https://doi.org/10.1007/s11307-019-01403-9
Autor:
Luc Zimmer, Janus H. Magnussen, Gilles Tamagnan, Matthias M. Herth, Olivier Barret, Agnete Dyssegaard, Szabolcs Lehel, Cristian Constantinescu, Thierry Billard, Gitte M. Knudsen, Julie Colomb, Hanne D. Hansen
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals
Journal of Labelled Compounds and Radiopharmaceuticals, Wiley-Blackwell, 2019, 62 (1), pp.34-42. ⟨10.1002/jlcr.3692⟩
Journal of Labelled Compounds and Radiopharmaceuticals, Wiley-Blackwell, 2019, 62 (1), pp.34-42. ⟨10.1002/jlcr.3692⟩
So far, no suitable 5-HT7 R radioligand exists for clinical positron emission tomography (PET) imaging. [18 F]2FP3 was first tested in vivo in cats, and the results were promising for further evaluations. Here, we evaluate the radioligand in pigs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c76a97d2b787ffae64009a459f4160
https://doi.org/10.1002/jlcr.3692
https://doi.org/10.1002/jlcr.3692
Autor:
Hanne D, Hansen, Cristian C, Constantinescu, Olivier, Barret, Matthias M, Herth, Janus H, Magnussen, Szabolcs, Lehel, Agnete, Dyssegaard, Julie, Colomb, Thierry, Billard, Luc, Zimmer, Gilles, Tamagnan, Gitte M, Knudsen
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 62(1)
So far, no suitable 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3d86e4503b7266fb11003035f4ef49c
https://pubmed.ncbi.nlm.nih.gov/30414212
https://pubmed.ncbi.nlm.nih.gov/30414212
Autor:
Agnete Dyssegaard, Jesper L. Kristensen, Hanne D. Hansen, Szabolcs Lehel, Matthias M. Herth, Gitte M. Knudsen, Janus H. Magnussen, Nikolas Stroth, Valdemar L. Andersen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1901-1904
E-55888 has been identified as a selective serotonin 7 (5-HT 7 ) receptor agonist. In this study, we describe the synthesis, radiolabeling and in vivo evaluation of [ 11 C]E-55888 as a radioligand for positron emission tomography (PET) imaging. [ 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b2e4893f4eebadbceda4d98e762faa
https://doi.org/10.1016/j.bmcl.2015.03.039
https://doi.org/10.1016/j.bmcl.2015.03.039
Autor:
Janus H. Magnussen, Martin Holst Friborg Pedersen, Cornelius K. Donat, Dan Peters, Anders Ettrup, Gitte M. Knudsen, Jens D. Mikkelsen
Publikováno v:
European journal of pharmacology. 762
The neuronal α7 nicotinic acetylcholine receptor is a homo-pentameric ligand-gated ion channel that is a promising drug target for cognitive deficits in Alzheimer׳s disease and schizophrenia. We have previously described (11)C-NS14492 as a suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0673906fee1d83350924a7ff38c656
https://pubmed.ncbi.nlm.nih.gov/25941084
https://pubmed.ncbi.nlm.nih.gov/25941084
Autor:
Cornelius K. Donat, Janus H. Magnussen, Gitte M. Knudsen, Anders Ettrup, Dan Peters, Martin Holst Friborg Pedersen, Jens D. Mikkelsen
Publikováno v:
Biochemical Pharmacology. 97:629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ca0beb4235d3c4c2ed94c8f5ab3e27
https://doi.org/10.1016/j.bcp.2015.08.025
https://doi.org/10.1016/j.bcp.2015.08.025