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Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α‐XBP1 pathway.

Autor: D'Amico, Domenico, Biondi, Olivier, Januel, Camille, Bezier, Cynthia, Sapaly, Delphine, Clerc, Zoé, El Khoury, Mirella, Sundaram, Venkat Krishnan, Houdebine, Léo, Josse, Thibaut, Della Gaspera, Bruno, Martinat, Cécile, Massaad, Charbel, Weill, Laure, Charbonnier, Frédéric

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Autor: Levin-Konigsberg R; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA., Mitra K; Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Neuroscience Institute, The University of Chicago, Chicago, IL 60637, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA., Spees K; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA., Nigam A; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Liu K; Department of Biology, Stanford University, Stanford, CA 94305, USA., Januel C; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Hivare P; Neuroscience Institute, The University of Chicago, Chicago, IL 60637, USA., Arana SM; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA., Prolo LM; Department of Neurosurgery, Stanford School of Medicine, Stanford, CA 94305, USA., Kundaje A; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Leonetti MD; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Krishnan Y; Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Neuroscience Institute, The University of Chicago, Chicago, IL 60637, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA., Bassik MC; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA; Program in Chemistry, Engineering, and Medicine for Human Health, Stanford University, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford School of Medicine, Stanford, CA 94305, USA. Electronic address: bassik@stanford.edu.

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