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Autor:
Emma Spanjaard, Jelena R. Linnemann, Johan de Rooij, Patricia M. Brouwer, Jantine J.G. van Dijk, On Ying A. Chan, Fried J. T. Zwartkruis, Holger Rehmann, Johannes L. Bos, Stephan Huveneers, Willem-Jan Pannekoek, Anne Jan van der Meer
Publikováno v:
Cellular Signalling, 23(12), 2056-2064. Elsevier B.V.
Epac1 and its effector Rap1 are important mediators of cAMP induced tightening of endothelial junctions and consequential increased barrier function. We have investigated the involvement of Rap1 signalling in basal, unstimulated, barrier function of