GABA-mediated inhibition of human CD4 ⁺ T cell functions is enhanced by insulin but impaired by high glucose levels.

Autor: Jin Z; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Hammoud H; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Bhandage AK; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Korol SV; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Trujeque-Ramos O; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Koreli S; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Gong Z; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Chowdhury AI; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Sandbaumhüter FA; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Jansson ET; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Lindsay RS; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Christoffersson G; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Andrén PE; Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Carlsson PO; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Bergsten P; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Kamali-Moghaddam M; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Birnir B; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden. Electronic address: bryndis.birnir@mcb.uu.se.

Publikováno v: EBioMedicine [EBioMedicine] 2024 Jul; Vol. 105, pp. 105217. Date of Electronic Publication: 2024 Jun 28.

Label-Free Quantitative Thermal Proteome Profiling Reveals Target Transcription Factors with Activities Modulated by MC3R Signaling.

Autor: Sandbaumhüter FA; Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden., Nezhyva M; Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden., Andrén PE; Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.; Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, 751 24 Uppsala, Sweden., Jansson ET; Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.

Publikováno v: Analytical chemistry [Anal Chem] 2023 Oct 17; Vol. 95 (41), pp. 15400-15408. Date of Electronic Publication: 2023 Oct 07.

Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis-Mass Spectrometry.

Autor: Aerts JT; Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24 Uppsala, Sweden., Andrén PE; Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24 Uppsala, Sweden.; Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, SE-751 24 Uppsala, Sweden., Jansson ET; Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24 Uppsala, Sweden.

Publikováno v: Journal of proteome research [J Proteome Res] 2023 Apr 07; Vol. 22 (4), pp. 1377-1380. Date of Electronic Publication: 2023 Mar 03.

Enantioselective CE-MS analysis of ketamine metabolites in urine.

Autor: Sandbaumhüter FA; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Aerts JT; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Theurillat R; Clinical Pharmacology Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland., Andrén PE; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, Uppsala, Sweden., Thormann W; Clinical Pharmacology Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland., Jansson ET; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

Publikováno v: Electrophoresis [Electrophoresis] 2023 Jan; Vol. 44 (1-2), pp. 125-134. Date of Electronic Publication: 2022 Dec 09.

Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide.

Autor: Rofo F; Protein Drug Design, Faculty of Pharmacy, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Sandbaumhüter FA; Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Chourlia A; Protein Drug Design, Faculty of Pharmacy, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Metzendorf NG; Protein Drug Design, Faculty of Pharmacy, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Morrison JI; Protein Drug Design, Faculty of Pharmacy, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Syvänen S; Department of Public Health and Caring Sciences, Rudbeck Laboratory, Uppsala University, 75185 Uppsala, Sweden., Andrén PE; Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden.; Science for Life Laboratory, Spatial Mass Spectrometry, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Jansson ET; Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden., Hultqvist G; Protein Drug Design, Faculty of Pharmacy, Biomedical Centre 591, Uppsala University, 75124 Uppsala, Sweden.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jul 07; Vol. 12 (13), pp. 2529-2541. Date of Electronic Publication: 2021 Jun 25.