Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janson C. H. Leung"'
Autor:
Teresa Lambe, Anastasia Nijnik, Karlee Silver, Richard J. Cornall, Helen Ferry, Graham Lewis, Janson C. H. Leung
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089ce042f25aa4c0f79575c3f0351828
https://ora.ox.ac.uk/objects/uuid:7028df01-9f5e-4610-bc4a-1d425b5d250a
https://ora.ox.ac.uk/objects/uuid:7028df01-9f5e-4610-bc4a-1d425b5d250a
Positive and negative signals from self-Ags shape the B cell repertoire and the development of distinct B cell subsets, but little is known about what distinguishes these signals. To address this question, we have studied the development of anti-hen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50522c3f2dad8c8826be13cf84fe2ed3
https://doi.org/10.4049/jimmunol.176.12.7402
https://doi.org/10.4049/jimmunol.176.12.7402
Autor:
Helen Ferry, Janson C. H. Leung, John V. Forrester, Kimmo Makinen, Teresa Lambe, Tiphaine Bouriez-Jones, Karlee Silver, Richard J. Cornall, Tanya L. Crockford
Publikováno v:
ResearcherID
Better understanding of tolerance and autoimmunity toward melanocyte-specific Ags is needed to develop effective treatment for vitiligo and malignant melanoma; yet, a systematic assessment of these mechanisms has been hampered by the difficulty in tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a1e3627ac2ee3d9fad015e3e114434
https://doi.org/10.4049/jimmunol.177.5.3055
https://doi.org/10.4049/jimmunol.177.5.3055
Autor:
Richard J. Cornall, Janson C. H. Leung, John V. Forrester, Helen Ferry, Kimmo Makinen, Leena Peltonen, Teresa Lambe, Tanya L. Crockford, John M. Nickerson, Hui R. Jiang, Tiphaine Bouriez-Jones
Publikováno v:
ResearcherID
Autoimmune uveoretinitis accounts for at least 10% of worldwide blindness, yet it is unclear why tolerance to retinal Ags is so fragile and, particularly, to what extent this might be due to defects in peripheral tolerance. To address this issue, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c383d85eb8bb1f0a1752fdf476b909de
https://doi.org/10.4049/jimmunol.178.7.4276
https://doi.org/10.4049/jimmunol.178.7.4276
Autor:
Janson C. H. Leung, Richard J. Cornall, Anastasia Nijnik, Helen Ferry, Teresa Lambe, Eleni Rapsomaniki, Angelika Daser, Graham Lewis, Christopher C. Goodnow
Publikováno v:
International Immunology. 18:1127-1137
The MRL-lpr/lpr mouse strain is a commonly used model of the human autoimmune disease systemic lupus erythematosus (SLE). Although much is known about the contribution of the lpr Fas mutation to B cell tolerance breakdown, the role of the genetic bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e0d752a1b5f4667d6dec2b5aae2605
https://doi.org/10.1093/intimm/dxl047
https://doi.org/10.1093/intimm/dxl047
Autor:
Helen Ferry, Hui-Rong Jiang, Tanya L. Crockford, John V. Forrester, Janson C. H. Leung, John M. Nickerson, Richard J. Cornall
Publikováno v:
Clinical Science. 104:49P-49P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4842ad7c7e9afd62b3802f36cc2875f1
https://doi.org/10.1042/cs104049p
https://doi.org/10.1042/cs104049p
Autor:
Anastasia Nijnik, Helen Ferry, Graham Lewis, Eleni Rapsomaniki, Janson C. H. Leung, Angelika Daser, Teresa Lambe, Christopher C. Goodnow, Richard J. Cornall
Publikováno v:
International Immunology; Jul2006, Vol. 18 Issue 7, p1127-1137, 11p