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Autor:
Luc Dirix, Manon T. Huizing, Hans Wildiers, Eveline De Cuypere, Sarah Khan, Frederik Marmé, Carolina P. Schröder, Anne C Armstrong, Andreas Schneeweiss, Jans Huober, Frédéric Triebel
Publikováno v:
Cancer Research. 80:OT1-01
Background: Eftilagimod alpha (efti, previously IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II and mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Efti may lead to the activation of the