Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat.

Autor: Piel S; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA. piels@chop.edu.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA. piels@chop.edu., Janowska JI; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Ward JL; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., McManus MJ; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Aronowitz DI; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Janowski PK; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Starr J; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Hook JN; Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, USA., Hefti MM; Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, USA., Clayman CL; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA., Elmér E; Abliva AB, Lund, Sweden.; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Hansson MJ; Abliva AB, Lund, Sweden.; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Jang DH; Department of Emergency Medicine, Division of Medical Toxicology, University of Pennsylvania School of Medicine, Philadelphia, USA., Karlsson M; Department of Neurosurgery, Rigshospitalet, Copenhagen, Denmark., Ehinger JK; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Otorhinolaryngology, Head and Neck Surgery, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden., Kilbaugh TJ; Resuscitation Science Center of Emphasis, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.; Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA.

Publikováno v: Molecular and cellular biochemistry [Mol Cell Biochem] 2023 Jun; Vol. 478 (6), pp. 1231-1244. Date of Electronic Publication: 2022 Oct 25.