Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janos Szollosi"'
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate that carries a cytotoxic drug (DM1) to HER2-positive cancer. The target of T-DM1 (HER2) is present also on cancer-derived exosomes. We hypothesized that exosome-bound T-D
Externí odkaz:
https://doaj.org/article/5e7c9937327e48098ffdd421d894b730
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The actual interaction between signaling species in cellular processes is often more important than their expression levels. Förster resonance energy transfer (FRET) is a popular tool for studying molecular interactions, since it is highly
Externí odkaz:
https://doaj.org/article/01884f0f40104be2a06fe74f594bcc64
Publikováno v:
Clinical Cancer Updates. 2:18-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72d3a2ed2ea97649a95edb701ad60913
https://doi.org/10.3816/ccu.2008.n.004
https://doi.org/10.3816/ccu.2008.n.004
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The epidermal growth factor (EGF) receptor (EGFR) undergoes ligand-dependent dimerization to initiate transmembrane signaling. Although crystallographic structures of the extracellular and kinase domains are available, ligand binding has not been qua
Externí odkaz:
https://doaj.org/article/50cbf683dd2d43549e648ebc418211c7
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1681-1691 (2017)
The dipole potential generating an electric field much stronger than any other type of membrane potential influences a wide array of phenomena, ranging from passive permeation to voltage-dependent conformational changes of membrane proteins. It is ge
Externí odkaz:
https://doaj.org/article/66c505eff6f14a978134da239ccb5b47
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22578-22620 (2015)
The review will discuss in detail the effects of polyphenols on breast cancer, including both the advantages and disadvantages of the applications of these natural compounds. First, we focus on the characterization of the main classes of polyphenols
Externí odkaz:
https://doaj.org/article/b5e17f1c75cc44a0810a4bfea8c6556e
Autor:
Anna Király, Tímea Váradi, Tímea Hajdu, Ralph Rühl, Carlos M. Galmarini, János Szöllősi, Peter Nagy
Publikováno v:
Marine Drugs, Vol 11, Iss 12, Pp 4858-4875 (2013)
The mechanism of action of elisidepsin (PM02734, Irvalec®) is assumed to involve membrane permeabilization via attacking lipid rafts and hydroxylated lipids. Here we investigate the role of hypoxia in the mechanism of action of elisidepsin. Culturin
Externí odkaz:
https://doaj.org/article/f51e71c5d41e46428207b192790bf399