Výsledky vyhledávání - "Jano Dicroce Giacobini"

Supplementary Table S1 and Supplementary Figures S1-S6 from Cell Death Induced by Cationic Amphiphilic Drugs Depends on Lysosomal Ca2+ Release and Cyclic AMP

Autor: Marja Jäättelä, Mikkel Rohde, Kenji Maeda, Jano Dicroce Giacobini, Bin Liu, Atul Anand

Table S1 list the resources used. Figures S1-S5 supplement the data presented in figures 1-6 and Figure S6 provides a schematic presentation of the proposed CAD signaling pathway.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d574da403e301013d74b624828ea5c
https://doi.org/10.1158/1535-7163.22509318

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Comprehensive Evaluation of a Quantitative Shotgun Lipidomics Platform for Mammalian Sample Analysis on a High-Resolution Mass Spectrometer

Autor: Klaus Kaae Andersen, Elena Papaleo, Kenji Maeda, Marja Jäättelä, Inger Ødum Nielsen, André Vidas Olsen, Jano Dicroce-Giacobini, Mesut Bilgin

Publikováno v: Journal of the American Society for Mass Spectrometry. 31:894-907

Shotgun lipidomics is a powerful tool that enables simultaneous and fast quantification of diverse lipid classes through mass spectrometry based analyses of directly infused crude lipid extracts. We present here a shotgun lipidomics platform establis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6812fdf35e410414239e739cecf41cb0
https://doi.org/10.1021/jasms.9b00136

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Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells

Autor: Monika Mortensen, Inger Ødum Nielsen, Kenji Maeda, Anna Sofie Holm Jonassen, Mesut Bilgin, Marja Jäättelä, Line Groth-Pedersen, Kjeld Schmiegelow, Jano Dicroce-Giacobini

Publikováno v: Metabolomics. 16

Repurposing of cationic amphiphilic drugs (CADs) emerges as an attractive therapeutic solution against various cancers, including leukemia. CADs target lysosomal lipid metabolism and preferentially kill cancer cells via induction of lysosomal membran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5540fb88af4a28f781bc82e4a9961806
https://doi.org/10.1007/s11306-020-01710-1

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Cell death induced by cationic amphiphilic drugs depends on lysosomal Ca(2+) release and cyclic AMP

Autor: Kenji Maeda, Bin Liu, Jano Dicroce Giacobini, Mikkel Rohde, Marja Jäättelä, Atul Anand

Publikováno v: Mol Cancer Ther

Repurposing cationic amphiphilic drugs (CAD) for cancer treatment is emerging as an attractive means to enhance the efficacy of chemotherapy. Many commonly used CADs, including several cation amphiphilic antihistamines and antidepressants, induce can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2052b49ffa5fe645225b515f7005c8ef
https://europepmc.org/articles/PMC7611280/

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