Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janny Tilma"'
Autor:
Vera M. Kissling, Giordano Reginato, Eliana Bianco, Kristina Kasaciunaite, Janny Tilma, Gea Cereghetti, Natalie Schindler, Sung Sik Lee, Raphaël Guérois, Brian Luke, Ralf Seidel, Petr Cejka, Matthias Peter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The Mre11-Rad50 (MR) complex has key functions in the detection, signaling and repair of DNA breaks. Here the authors use transmission electron microscopy to show MR oligomerization is governed by a small beta-sheet protruding from the head domain of
Externí odkaz:
https://doaj.org/article/3b0bb9efd9d04d24afb66624d538d569
Autor:
Giordano Reginato, Sung Sik Lee, Janny Tilma, Vera M. Kissling, Petr Cejka, Ralf Seidel, Gea Cereghetti, Raphael Guerois, Eliana Bianco, Kristina Kasaciunaite, Matthias Peter
The conserved Mre11-Rad50 (MR) complex is crucial for the detection, signaling, end tethering and processing of DNA double-strand breaks (DSBs). While it was known for decades that MR foci formation at DSBs accompanies repair, the underlying molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::985d2c97de693e99e52d5b7e070088a4
https://doi.org/10.21203/rs.3.rs-811984/v1
https://doi.org/10.21203/rs.3.rs-811984/v1
Autor:
Vera M, Kissling, Giordano, Reginato, Eliana, Bianco, Kristina, Kasaciunaite, Janny, Tilma, Gea, Cereghetti, Natalie, Schindler, Sung Sik, Lee, Raphaël, Guérois, Brian, Luke, Ralf, Seidel, Petr, Cejka, Matthias, Peter
Publikováno v:
Nature communications. 13(1)
The conserved Mre11-Rad50 complex is crucial for the detection, signaling, end tethering and processing of DNA double-strand breaks. While it is known that Mre11-Rad50 foci formation at DNA lesions accompanies repair, the underlying molecular assembl