Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jannie Assenholt"'
Autor:
Jane Hübertz Frederiksen, Ulf Birkedal, Sarah Bachmann, Elisabeth Victoria Eliesen, Lene Juel Rasmussen, Katja Venborg Pedersen, Lana Al‐Zehhawi, Susanne E. Boonen, Lotte Krogh, Karina Rønlund, Lise Graversen, Jannie Assenholt, Kjeld Schmiegelow, Karin Wadt, Anne‐Marie Gerdes, Thomas v. O. Hansen
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Background Pathogenic variants in the mismatch repair genes are associated with an elevated lifetime risk of colorectal cancer (CRC). We previously identified two variants of uncertain significance (VUS) in the MLH1 gene, c.696_698del, p.(Cy
Externí odkaz:
https://doaj.org/article/3138d238b0bc48cdadc8df08238a908f
Autor:
Ahmed Hussein Zedan, Torben Frøstrup Hansen, Jannie Assenholt, Mindaugas Pleckaitis, Jonna Skov Madsen, Palle Jörn Sloth Osther
Publikováno v:
Tumor Biology, Vol 40 (2018)
Prostate cancer is the most common cancer among men in the western world. Clinical practice is continuously challenged by the pitfalls of the available diagnostic tools. microRNAs may represent promising biomarkers in many types of human cancers, inc
Externí odkaz:
https://doaj.org/article/25e1c63eb4d0472286e956f7de14e8d0
Autor:
Torben Hansen, Ahmed Hussein Zedan, Jannie Assenholt, Jonna Skov Madsen, Palle Jørn Sloth Osther
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Zedan, A H, Osther, P J S, Assenholt, J, Madsen, J S & Hansen, T F 2020, ' Circulating miR-141 and miR-375 are associated with treatment outcome in metastatic castration resistant prostate cancer ', Scientific Reports, vol. 10, 227 . https://doi.org/10.1038/s41598-019-57101-7
Scientific Reports
Zedan, A H, Osther, P J S, Assenholt, J, Madsen, J S & Hansen, T F 2020, ' Circulating miR-141 and miR-375 are associated with treatment outcome in metastatic castration resistant prostate cancer ', Scientific Reports, vol. 10, 227 . https://doi.org/10.1038/s41598-019-57101-7
Scientific Reports
Metastatic castration resistant prostate cancer (mCRPC) is associated with high mortality, where monitoring of disease activity is still a major clinical challenge. The role of microRNAs (miRs) has been widely investigated in prostate cancer with bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6481d4e647585d4519bec0cd3a6c321
https://doi.org/10.1038/s41598-019-57101-7
https://doi.org/10.1038/s41598-019-57101-7
Autor:
Torben Hansen, Jonna Skov Madsen, Ahmed Hussein Zedan, Jannie Assenholt, Palle Jørn Sloth Osther
Publikováno v:
The Prostate
Zedan, A H, Hansen, T F, Assenholt, J, Madsen, J S & Osther, P J S 2019, ' Circulating miRNAs in localized/locally advanced prostate cancer patients after radical prostatectomy and radiotherapy ', The Prostate, vol. 79, no. 4, pp. 425-432 . https://doi.org/10.1002/pros.23748
Zedan, A H, Hansen, T F, Assenholt, J, Madsen, J S & Osther, P J S 2019, ' Circulating miRNAs in localized/locally advanced prostate cancer patients after radical prostatectomy and radiotherapy ', The Prostate, vol. 79, no. 4, pp. 425-432 . https://doi.org/10.1002/pros.23748
BACKGROUND: Overtreatment is a well-known clinical challenge in local prostate cancer (PCa). Although risk assessment models have contributed to a better stratification of patients with local PCa, a tailored management is still in its infancy. Over t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0329e6978610487c78ad05ed1b736bdb
https://doi.org/10.1002/pros.23748
https://doi.org/10.1002/pros.23748
Autor:
Ahmed Hussein Zedan, Torben Hansen, Palle Jørn Sloth Osther, Jannie Assenholt, Jonna Skov Madsen
Publikováno v:
Zedan, A H, Osther, P J S, Assenholt, J, Madsen, J S & Hansen, T 2019, ' Association between circulating miRNA-141 and miRNA-375 and treatment outcome in metastatic castration-resistant prostate cancer ', Journal of Clinical Oncology, vol. 37, no. 15 Supplement, e16507 . https://doi.org/10.1200/JCO.2019.37.15suppl.e16507
e16507 Background: Metastatic castration resistant prostate cancer (mCRPC) is associated with high mortality. Monitoring of disease activity at this stage, with lack of validated prognostic models, is still a major clinical challenge. The role of mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ed8fffdf8f3c1489b31cd11db479c4
https://doi.org/10.1200/jco.2019.37.15_suppl.e16507
https://doi.org/10.1200/jco.2019.37.15_suppl.e16507
Autor:
Jannie Assenholt, Domenico Libri, John Mouaikel, Mathieu Rougemaille, Cyril Saguez, Torben Heick Jensen
Publikováno v:
Assenholt, J, Mouaikel, J, Saguez, C, Rougemaille, M, Libri, D & Jensen, T H 2011, ' Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae ', RNA, vol. 17, no. 10, pp. 1788-1794 . https://doi.org/10.1261/rna.2919911
Production of messenger ribonucleoprotein particles (mRNPs) is subjected to quality control (QC). In Saccharomyces cerevisiae, the RNA exosome and its cofactors are part of the nuclear QC machinery that removes, or stalls, aberrant molecules, thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2672ca6fa10183515cf40820649793c9
https://doi.org/10.1261/rna.2919911
https://doi.org/10.1261/rna.2919911
Autor:
Mindaugas Pleckaitis, Jannie Assenholt, Torben Hansen, Jonna Skov Madsen, Ahmed Hussein Zedan, Palle Jørn Sloth Osther
Publikováno v:
Zedan, A H, Hansen, T F, Assenholt, J, Pleckaitis, M, Madsen, J S & Osther, P J S 2018, ' microRNA expression in tumour tissue and plasma in patients with newly diagnosed metastatic prostate cancer ', Tumor Biology, vol. 40, no. 5, pp. 1-11 . https://doi.org/10.1177/1010428318775864
Tumor Biology, Vol 40 (2018)
Tumor Biology, Vol 40 (2018)
Prostate cancer is the most common cancer among men in the western world. Clinical practice is continuously challenged by the pitfalls of the available diagnostic tools. microRNAs may represent promising biomarkers in many types of human cancers, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331b3047250783cf1312c201796a08f4
https://doi.org/10.1177/1010428318775864
https://doi.org/10.1177/1010428318775864
Autor:
Ditlev E. Brodersen, Jannie Assenholt, Torben Heick Jensen, John Mouaikel, Domenico Libri, Kasper R. Andersen
Publikováno v:
Assenholt, J, Mouaikel, J, Andersen, K R, Brodersen, D E, Libri, D & Jensen, T H 2008, ' Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants ', RNA, vol. 14, no. 11, pp. 2305-13 . https://doi.org/10.1261/rna.1108008
Production of aberrant messenger ribonucleoprotein particles (mRNPs) is subject to quality control (QC). In yeast strains carrying mutations of the THO complex, transcription induction triggers a number of interconnected QC phenotypes: (1) rapid degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78c3d912a79a50eb43f372c279f0df3
https://doi.org/10.1261/rna.1108008
https://doi.org/10.1261/rna.1108008
Autor:
Line Lindegaard Haaning, Katharine C. Abruzzi, Torben Heick Jensen, Jens Raabjerg Olsen, Sylvia Denome, Jannie Assenholt, Michael Rosbash
Publikováno v:
Abruzzi, K, Denome, S, Olesen, J R, Assenholt, J, Haaning, L L, Jensen, T H & Rosbash, M 2007, ' A Novel Plasmid-Based Microarray Screen Identifies Suppressors of rrp6 Δ in Saccharomyces cerevisiae ', Molecular and Cellular Biology, vol. 27, no. 3, pp. 1044-1055 .
Genetic screens in Saccharomyces cerevisiae provide novel information about interacting genes and pathways. We screened for high-copy-number suppressors of a strain with the gene encoding the nuclear exosome component Rrp6p deleted, with either a tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a9e6d1aacab3d4e1333a08d271220f
https://pure.au.dk/portal/da/publications/a-novel-plasmidbased-microarray-screen-identifies-suppressors-of-rrp6-in-saccharomyces-cerevisiae(fb6225b0-679e-11dd-9251-000ea68e967b).html
https://pure.au.dk/portal/da/publications/a-novel-plasmidbased-microarray-screen-identifies-suppressors-of-rrp6-in-saccharomyces-cerevisiae(fb6225b0-679e-11dd-9251-000ea68e967b).html
Autor:
Jannie Assenholt, John Mouaikel, Kasper Røjkjær Andersen, Ditlev Brodersen, Domenico Libri, Torben Heick Jensen
Publikováno v:
Aarhus University
Assenholt, J, Mouaikel, J, Andersen, K R, Brodersen, D E, Libri, D & Jensen, T H 2008, ' Exonucleolysis is required for several aspects of nuclear quality control of mRNA ', RNA 2008, Berlin, Germany, 28/07/2008-03/08/2008 .
Assenholt, J, Mouaikel, J, Andersen, K R, Brodersen, D E, Libri, D & Jensen, T H 2008, ' Exonucleolysis is required for several aspects of nuclear quality control of mRNA ', RNA 2008, Berlin, Germany, 28/07/2008-03/08/2008 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3fda213c55bfe5fa61d6ae46c4ac59ea
https://pure.au.dk/portal/en/publications/exonucleolysis-is-required-for-several-aspects-of-nuclear-quality-control-of-mrna(d4eb0640-63ac-11dd-9251-000ea68e967b).html
https://pure.au.dk/portal/en/publications/exonucleolysis-is-required-for-several-aspects-of-nuclear-quality-control-of-mrna(d4eb0640-63ac-11dd-9251-000ea68e967b).html