Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jannette van Ark-Otte"'
Autor:
Paul van der Valk, Pieter E. Postmus, Simone W. Span, Jannette van Ark-Otte, Giuseppe Giaccone, A.-M. C. Dingemans, Giorgio V. Scagliotti
Publikováno v:
Lung Cancer. 32:117-128
Resistance to chemotherapy is common in non-small cell lung cancer. The aim of this study was to investigate the prognostic impact of in vitro established drug resistance markers on the response to chemotherapy in patients with advanced non-small cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8cdc4c15c9ee4c1851300eb02ece62
https://doi.org/10.1016/s0169-5002(00)00224-5
https://doi.org/10.1016/s0169-5002(00)00224-5
Autor:
Herbert M. Pinedo, Rik J. Scheper, A.-M. C. Dingemans, M. J. Flens, Adi F. Gazdar, Giuseppe Giaccone, G. Rubio, Jannette van Ark-Otte, Henk J. Broxterman
Publikováno v:
International Journal of Cancer. 66:760-767
The multidrug resistance-associated protein (MRP), a new membrane transporter related to non-Pgp multidrug resistance, is overexpressed in some drug-selected cancer-cell lines. The role of MRP in unselected cell lines and in human cancer is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0fb8c0ff8355aa2fedd0a783427d755
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<760::aid-ijc9>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<760::aid-ijc9>3.0.co
Autor:
Jan M. M. Walboomers, Giuseppe Giaccone, Paul van der Valk, Giorgio V. Scagliotti, Jannette van Ark-Otte, Rafael Lopez, Otilia Dalesio, Herbert M. Pinedo, Giovanni Capranico, Franco Zunino, G. Rubio
Publikováno v:
Biochimica et biophysica acta. 1264(3)
DNA topoisomerases are ubiquitous nuclear enzymes, and important targets of cancer chemotherapy. Expression of topoisomerase genes is often correlated with in vitro chemosensitivity. We investigated the expression of the topoisomerase genes in normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59e939f8f543e731f45d9ff78759fd6
https://pubmed.ncbi.nlm.nih.gov/8547322
https://pubmed.ncbi.nlm.nih.gov/8547322
Autor:
Rik J. Scheper, Miguel A. Izquierdo, Jose R. Germa-Lluch, Paul van der Valk, Ryuzo Ueda, G. Rubio, Takashi Takahashi, Jannette van Ark-Otte, Giuseppe Giaccone
Publikováno v:
The Journal of pathology. 177(3)
The c-kit proto-oncogene product and its ligand stem cell factor play an important role in haematopoiesis, spermatogenesis, and melanogenesis. Using an anti-c-kit antiserum raised against a synthetic peptide, we studied the immunohistochemical expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65027a98cab5ed4c86c84eadfec582a9
https://pubmed.ncbi.nlm.nih.gov/8551387
https://pubmed.ncbi.nlm.nih.gov/8551387
Autor:
Godefridus J. Peters, E. Smitskamp-Wilms, Giuseppe Giaccone, Jos H. Beijnen, Paulo E. Pizao, Jannette van Ark-Otte, Herbert M. Pinedo
Publikováno v:
Biochemical pharmacology. 48(6)
We have assessed the antiproliferative effects of a 24-hr exposure to the topoisomerase I inhibitors, topotecan and camptothecin, on two colon and one ovarian human tumor cell lines, cultured as subconfluent and as multilayered postconfluent cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bacda1e19d06e8b69196c4e54620c7
https://pubmed.ncbi.nlm.nih.gov/7945408
https://pubmed.ncbi.nlm.nih.gov/7945408
Autor:
Godefridus J. Peters, E. Smitskamp-Wilms, Lou A. Smets, Herbert M. Pinedo, Jannette van Ark-Otte, Paulo E. Pizao, Giuseppe Giaccone, Benjamin Winograd
Publikováno v:
European journal of cancer (Oxford, England : 1990). (11)
The cytotoxic effects of conventional (doxorubicin, 5-fluorouracil, cisplatin) and investigational (2′,2′-difluorodeoxycytidine, hexadecylphosphocholine, EO9, rhizoxin) anticancer drugs were studied in subconfluent and multilayered postconfluent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad54671449aec759bf6916bdbf4bafc3
https://pubmed.ncbi.nlm.nih.gov/8217364
https://pubmed.ncbi.nlm.nih.gov/8217364
Autor:
B. Winograd, Godefridus J. Peters, Herbert M. Pinedo, Paulo E. Pizao, Yvonne P. Keepers, Jannette van Ark-Otte
Publikováno v:
European journal of cancer (Oxford, England : 1990). 27(7)
The sulforhodamine B (SRB) protein stain assay was compared with the tetrazolium (MTT) colorimetric assay for in vitro chemosensitivity testing of various human tumour cell lines. The SRB assay provided a better linearity with cell number and a highe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c320bedb04fee81300718b4b23eeff07
https://pubmed.ncbi.nlm.nih.gov/1834124
https://pubmed.ncbi.nlm.nih.gov/1834124