Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jannel Acosta"'
Autor:
Leonardo Ortega, Crisleri Carrera, Carolina Muñoz-Flores, Santiago Salazar, Milton F. Villegas, María F. Starck, Ariel Valenzuela, Niza Agurto, Raquel Montesino, Allisson Astuya, Natalie Parra, Ercilia T. Pérez, Natacha Santibáñez, Alex Romero, Pamela Ruíz, Emilio Lamazares, Fátima Reyes, Oliberto Sánchez, Jorge R. Toledo, Jannel Acosta
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungi, viruses, and parasites. NK-lysin is a type of granulysin, a member of the saposin-like proteins family first isolated from a pig’s small intestine
Externí odkaz:
https://doaj.org/article/5a9fe38e9a21442d9d60b7bc9ce3877a
Autor:
Carolina Muñoz-Flores, Francisco J. Roa, Paulina Saavedra, Pablo Fuentealba, María F. Starck, Leonardo Ortega, Raquel Montesino, Ariel Valenzuela, Allisson Astuya, Natalie Parra, Iván González-Chavarría, Oliberto Sánchez, Jorge R. Toledo, Jannel Acosta
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23215- (2023)
Neuropeptides are a group of peptides derived from precursor proteins synthesized in neuronal and nonneuronal cells. The classical functions of neuropeptides have been extensively studied in mammals, including neuromodulation in the central nervous s
Externí odkaz:
https://doaj.org/article/82e5864f1efc43b589baca493a4ac8a7
Autor:
Santiago Salazar, María Francisca Starck, Milton F. Villegas, Jannel Acosta, Oliberto Sánchez, Eduardo Ramos, Estefanía Nova-Lamperti, Jorge R. Toledo, Paula Gädicke, Álvaro Ruiz, Alaín González, Raquel Montesino
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1817 (2023)
Previously, we designed a subunit vaccine candidate based on three L. intracellularis antigens with promising results in pigs. In this study, antigens were produced individually to achieve an even antigen ratio in the formulation. The emulsion charac
Externí odkaz:
https://doaj.org/article/d41362111947472c8ac17e82e4eb295f
Autor:
Ariel Valenzuela, Ignacia Rodríguez, Berta Schulz, Raúl Cortés, Jannel Acosta, Víctor Campos, Sebastián Escobar-Aguirre
Publikováno v:
Fishes, Vol 7, Iss 1, p 28 (2022)
Continuous photoperiod is extensively used in fish farming, to regulate the reproductive cycle, despite evidence suggesting that artificial photoperiods can act as a stressor and impair the immune system. We evaluated the potential effects of an arti
Externí odkaz:
https://doaj.org/article/3fd49594b5214aab96925fc792bcc601
Establishment of a production process for a novel vaccine candidate against Lawsonia intracellularis
Autor:
Jannel Acosta, Eduardo Ramos, Raquel Montesino, Jorge R. Toledo, Thelvia Ramos, Nicolas A. Gutiérrez, Santiago Salazar, Alaín González, Oliberto Sánchez, Claudia Altamirano
Publikováno v:
Electronic Journal of Biotechnology, Vol 50, Iss, Pp 45-52 (2021)
Background Lawsonia intracellularis remains a problem for the swine industry worldwide. Previously, we designed and obtained a vaccine candidate against this pathogen based on the chimeric proteins: OMP1c, OMP2c, and INVASc. These proteins formed inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac92082837ca4e1889e5c29cee77de5b
https://doi.org/10.1016/j.ejbt.2021.01.002
https://doi.org/10.1016/j.ejbt.2021.01.002
Autor:
Raquel Montesino, Pedro José Neira, Jorge R. Toledo, Frank Camacho, Oliberto Sánchez, María Angélica Contreras, Alaín González, Jannel Acosta, Luis Macaya
Publikováno v:
Biochemical Journal. 477:3299-3311
TNFα is a pro-inflammatory cytokine that is a therapeutic target for inflammatory autoimmune disorders. Thus, TNFα antagonists are successfully used for the treatment of these disorders. Here, new association patterns of rhTNFα and its antagonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e267bbdbf8a11a395b3af39c73c14be1
https://doi.org/10.1042/bcj20200568
https://doi.org/10.1042/bcj20200568
Publikováno v:
Fishshellfish immunology. 121
The membrane-anchored and soluble Toll-like Receptor 5 -TLR5M and TLR5S, respectively-from teleost recognize bacterial flagellin and induce the pro-inflammatory cytokines expression in a MyD88-dependent manner such as the TLR5 mammalian orthologous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6679465ddcfcb8d469ea8a5b052b2cfe
https://pubmed.ncbi.nlm.nih.gov/34998987
https://pubmed.ncbi.nlm.nih.gov/34998987
Autor:
Carolina Muñoz-Flores, Iván González-Chavarría, Felipe Sandoval, Francisco J. Roa, Paulo Palacios, Allisson Astuya, Khaterina Fernández, Claudia Altamirano, Alex Romero, Jannel Acosta, Jorge R. Toledo
Publikováno v:
Fishshellfish immunology. 125
The intensive salmon farming is associated with massive outbreaks of infections. The use of antibiotics for their prevention and control is related to damage to the environment and human health. Antimicrobial peptides (AMPs) have been proposed as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a0c7ceae8354fa38353de0c082e6fb
https://pubmed.ncbi.nlm.nih.gov/35537671
https://pubmed.ncbi.nlm.nih.gov/35537671
Autor:
Omar Farnós, Jannel Acosta, Nicolas A. Gutiérrez, Frank Camacho, Alaín González, M. Cortez-San Martin, Raquel Montesino, Oliberto Sánchez, S. Andrades, Jorge R. Toledo, A. Ruiz
Publikováno v:
Vaccine. 37:1340-1349
Proliferative enteropathy, caused by Lawsonia intracellularis, represents a threat for swine industry. Current vaccines are effective but difficult to obtain and scaled up, because of demanding bacterial culture conditions. In this work, a subunit va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ce6469e5d25f9751eba9497b600d0
https://doi.org/10.1016/j.vaccine.2019.01.029
https://doi.org/10.1016/j.vaccine.2019.01.029
Autor:
Oliberto Sánchez, Jorge R. Toledo, Natalie C. Parra, Alaín González, Felipe Bravo, Frank Camacho, Jannel Acosta
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Currently, the generation of cell lines for the production of recombinant proteins has the limitation of unstable gene expression due to the repeat-induced gene silencing or the loss of transgene copies resulting from recombination events. In this wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6f3440ce512a4245bf792fd51ee6f1
https://pubmed.ncbi.nlm.nih.gov/32732973
https://pubmed.ncbi.nlm.nih.gov/32732973