The influence of water of crystallization in NIR-based MDMA·HCl detection

Autor: Ruben F. Kranenburg, Henk-Jan Ramaker, Yannick Weesepoel, Peter W.F. Arisz, Peter H.J. Keizers, Annette van Esch, Cathelijne Zieltjens – van Uxem, Jorrit D.J. van den Berg, Janneke W. Hulshof, Sjors Bakels, Anouk M. Rijs, Arian C. van Asten

Publikováno v: Forensic Chemistry, 32:100464, 1-10. Elsevier BV
Kranenburg, R F, Ramaker, H J, Weesepoel, Y, Arisz, P W F, Keizers, P H J, van Esch, A, Zieltjens – van Uxem, C, van den Berg, J D J, Hulshof, J W, Bakels, S, Rijs, A M & van Asten, A C 2023, ' The influence of water of crystallization in NIR-based MDMA·HCl detection ', Forensic Chemistry, vol. 32, 100464, pp. 1-10 . https://doi.org/10.1016/j.forc.2022.100464
Forensic Chemistry 32 (2023)
Forensic Chemistry, 32

The large numbers of 3,4-methylenedioxy-N-methylamphetamine (MDMA) formulations encountered by the police and border security necessitates the need for safe, rapid and reliable tests to be performed on-site. Near-infrared (NIR) spectroscopy is a prom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd746fe11a1c3ed7ace5fc77833a849
https://doi.org/10.1016/j.forc.2022.100464

Identification of specific markers for amphetamines synthesized from glycidic acid pre-precursors and retrospective search in German profiling database

Autor: Frank M. Hauser, Thorsten Rößler, Janneke W. Hulshof, Michael Pütz

Publikováno v: Drug testing and analysisREFERENCES. 12(1)

The pre-precursor market and the clandestine production of amphetamine-type stimulants (ATS) has become more diverse in recent years. Besides α-phenylacetoacetonitrile (APAAN) and α-phenylacetoacetamide (APAA), glycidic acid derivatives and methyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1656720f01f0ed3fa1c73943f521bd2e
https://pubmed.ncbi.nlm.nih.gov/31471943

Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28

Autor: Jane Victorina, Silvina A. Fratantoni, Rob Leurs, Martine J. Smit, Iwan J. P. de Esch, Saskia Hulscher, Mark H.P. Verheij, Henry F. Vischer, Janneke W. Hulshof

Publikováno v: Bioorganic and Medicinal Chemistry. Elsevier Limited
Vischer, H F, Hulshof, J W, Hulscher, ST, S.A., F, Verheij, V J, Smit, M J, de Esch, I J P & Leurs, R 2009, ' Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28 ', Bioorganic and Medicinal Chemistry . https://doi.org/10.1016/j.bmc.2009.11.060

Human cytomegalovirus (HCMV) is a widespread human pathogen, possessing onco-modulatory properties. Constitutive signaling of the HCMV-encoded chemokine receptor US28 and its ability to bind a broad spectrum of chemokines might facilitate HCMV-associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007bf636aa838d53bc10b65e2f07445e
https://doi.org/10.1016/j.bmc.2009.11.060

Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28

Autor: Iwan J. P. de Esch, Martine J. Smit, Rob Leurs, Silvina A. Fratantoni, Mark H.P. Verheij, Henry F. Vischer, Janneke W. Hulshof

Publikováno v: Hulshof, J W, Vischer, H F, Verheij, M H P, Fratantoni, S A, Smit, M J, de Esch, I J P & Leurs, R 2006, ' Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28 ', Bioorganic and Medicinal Chemistry, vol. 14, no. 21, pp. 7213-30 . https://doi.org/10.1016/j.bmc.2006.06.054
Bioorganic and Medicinal Chemistry, 14(21), 7213-30. Elsevier Limited

G-protein coupled receptors encoded by viruses represent an unexplored class of potential drug targets. In this study, we describe the synthesis and pharmacological characterization of the first class of inverse agonists acting on the HCMV-encoded re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3901c1011387e3592ae7b46ecaaa1c9c
https://research.vu.nl/en/publications/4d8ea4a8-e140-4d0e-bdc0-95b5ef04ee47

Characterisation of aqueous waste produced during the clandestine production of amphetamine following the Leuckart route utilising solid-phase extraction gas chromatography-mass spectrometry and capillary electrophoresis with contactless conductivity dete

Autor: Janneke W. Hulshof, Frank M. Hauser, Michael Pütz, Ralf Zimmermann, Thorsten Rößler

Publikováno v: Drug Testing and Analysis

Chemical waste from the clandestine production of amphetamine is of forensic and environmental importance due to its illegal nature which often leads to dumping into the environment. In this study, 27 aqueous amphetamine waste samples from controlled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4b36ad549392624bee3d3dadd9c583