Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Janneke N Samsom"'
Autor:
Esther van Mastrigt, Salomé Zweekhorst, Bas Bol, Jeroen Tibboel, Joost van Rosmalen, Janneke N Samsom, André A Kroon, Johan C de Jongste, Irwin K M Reiss, Martin Post, Mariëlle W Pijnenburg
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0185969 (2018)
In an experimental mouse model we showed that ceramides play a role in the pathogenesis of bronchopulmonary dysplasia (BPD) and are a potential target for therapeutic intervention. We investigated whether ceramides are detectable in tracheal aspirate
Externí odkaz:
https://doaj.org/article/0586f3b65d20461b9a22de242c4cd07f
Autor:
Oriana Rossi, M Tanweer Khan, Martin Schwarzer, Tomas Hudcovic, Dagmar Srutkova, Sylvia H Duncan, Ellen H Stolte, Hana Kozakova, Harry J Flint, Janneke N Samsom, Hermie J M Harmsen, Jerry M Wells
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123013 (2015)
A decrease in the abundance and biodiversity of intestinal bacteria within the Firmicutes phylum has been associated with inflammatory bowel disease (IBD). In particular, the anti-inflammatory bacterium Faecalibacterium prausnitzii, member of the Fir
Externí odkaz:
https://doaj.org/article/416c46016e9b45f990e8cc362e750ea0
Autor:
Laurens E Nijhuis, Brenda J Olivier, Shobit Dhawan, Francisca W Hilbers, Louis Boon, Monika C Wolkers, Janneke N Samsom, Wouter J de Jonge
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85086 (2014)
Vagal nerve efferent activation has been shown to ameliorate the course of many inflammatory disease states. This neuro-modulatory effect has been suggested to rest on acetylcholine receptor (AChR) activation on tissue macrophages or dendritic cells
Externí odkaz:
https://doaj.org/article/dfdc05e47588496692381f69a3a5aafd
Autor:
Pieter P E van Lierop, Sigrid M Swagemakers, Charlotte I de Bie, Sabine Middendorp, Peter van Baarlen, Janneke N Samsom, Wilfred F J van Ijcken, Johanna C Escher, Peter J van der Spek, Edward E S Nieuwenhuis
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79549 (2013)
ObjectiveIn current clinical practice, optimal treatment of inflammatory bowel disease (IBD) aims at the induction and maintenance of clinical remission. Clinical remission is apparent when laboratory markers of inflammation are normal and clinical s
Externí odkaz:
https://doaj.org/article/efa5ee04a5654b7d8d2d142109cfe77b
Autor:
Marieke A van Leeuwen, M Fleur du Pré, Roy L van Wanrooij, Lilian F de Ruiter, H Rolien C Raatgeep, Dicky J Lindenbergh-Kortleve, Chris J Mulder, Lissy de Ridder, Johanna C Escher, Janneke N Samsom
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68432 (2013)
BACKGROUND: Celiac disease (CD) is an intestinal inflammation driven by gluten-reactive CD4(+) T cells. Due to lack of selective markers it has not been determined whether defects in inducible regulatory T cell (Treg) differentiation are associated w
Externí odkaz:
https://doaj.org/article/262ed0b6d37a4f688fa9507069969150
Autor:
Ruth Huizinga, Alistair S Easton, Anne M Donachie, Jim Guthrie, Wouter van Rijs, Astrid Heikema, Louis Boon, Janneke N Samsom, Bart C Jacobs, Hugh J Willison, Carl S Goodyear
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34416 (2012)
Guillain-Barré syndrome (GBS) is a post-infectious polyradiculoneuropathy, frequently associated with antecedent Campylobacter jejuni (C. jejuni) infection. The presence of sialic acid on C. jejuni lipo-oligosaccharide (LOS) is considered a risk fac
Externí odkaz:
https://doaj.org/article/a38e1a9a0b294a259dadfed98e6c5ecd
Autor:
Arno R. Bourgonje, Sietse J. Wichers, Shixian Hu, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Eleonora A. M. Festen, Gerard Dijkstra, Janneke N. Samsom, Rinse K. Weersma, Lieke M. Spekhorst
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Fatigue is a common and clinically challenging symptom in patients with inflammatory bowel diseases (IBD), occurring in ~ 50% of patients with quiescent disease. In this study, we aimed to investigate whether fatigue in patients with clinica
Externí odkaz:
https://doaj.org/article/1ca027029dca4c7482e2e2e9d0f9249d
Autor:
Sandrine Nugteren, Sjoerd H. den Uil, Pien M. Delis-van Diemen, Ytje Simons-Oosterhuis, Dicky J. Lindenbergh-Kortleve, Daniëlle H. van Haaften, Hein B. A. C. Stockmann, Joyce Sanders, Gerrit A. Meijer, Remond J. A. Fijneman, Janneke N. Samsom
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Secretory leukocyte protease inhibitor (SLPI) is a pleiotropic protein produced by healthy intestinal epithelial cells. SLPI regulates NF-κB activation, inhibits neutrophil proteases and has broad antimicrobial activity. Recently, increased
Externí odkaz:
https://doaj.org/article/1a4772d85e584b999d43df4fe8fa2f8c
Autor:
Justin Jacobse, Rachel E. Brown, Jing Li, Jennifer M. Pilat, Ly Pham, Sarah P. Short, Christopher T. Peek, Andrea Rolong, M. Kay Washington, Ruben Martinez-Barricarte, Mariana X. Byndloss, Catherine Shelton, Janet G. Markle, Yvonne L. Latour, Margaret M. Allaman, James E. Cassat, Keith T. Wilson, Yash A. Choksi, Christopher S. Williams, Ken S. Lau, Charles R. Flynn, Jean-Laurent Casanova, Edmond H.H.M. Rings, Janneke N. Samsom, Jeremy A. Goettel
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112128- (2023)
Summary: The cytokine interleukin-23 (IL-23) is involved in the pathogenesis of inflammatory and autoimmune conditions including inflammatory bowel disease (IBD). IL23R is enriched in intestinal Tregs, yet whether IL-23 modulates intestinal Tregs rem
Externí odkaz:
https://doaj.org/article/26b1ca6a3bad4a7d8ad24a3662d8812c
Autor:
Maria M E Jongsma, Lea M M Costes, Irma Tindemans, Martinus A Cozijnsen, Rolien (H) C Raatgreep, Merel van Pieterson, Yunlei Li, Johanna C Escher, Lissy de Ridder, Janneke N Samsom
Publikováno v:
Journal of Crohn's and Colitis.
Background Despite its efficacy, rational guidance for starting/stopping first-line biologic treatment in individual paediatric Crohn’s disease [CD] patients is needed. We assessed how serum immune profiles before and after first-line infliximab [F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fb4755f24811bdd230284d5b2e54e2
https://pure.eur.nl/en/publications/6b82993b-816a-4221-aa96-349e1987cbdb
https://pure.eur.nl/en/publications/6b82993b-816a-4221-aa96-349e1987cbdb