Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Janneke M. Meulenberg"'
Autor:
Stephanie van de Wall, Janneke M. Meulenberg, Baukje Nynke Hoogeboom, Jessica Sluis, Coba J. van Zanten, Joke Regts, Marco de Bruyn, Toos Daemen, Fenne L. Komdeur, Jos G. W. Kosterink, Amrita Singh, Ed Schuuring, Jan Wilschut, Derk P. Allersma, Ruben Marra, Annemarie Boerma, Ate G.J. van der Zee, Annelies Jorritsma-Smit, Cesar Oyarce, Hans W. Nijman, N Werner, R. Yigit, S. T. Paijens
Publikováno v:
Mol Ther
Molecular Therapy, 29(2), 611-625. CELL PRESS
Molecular therapy, 29(2), 611-625. Nature Publishing Group
Molecular Therapy
Molecular Therapy, 29(2), 611-625. CELL PRESS
Molecular therapy, 29(2), 611-625. Nature Publishing Group
Molecular Therapy
A first-in-human phase I trial of Vvax001, an alphavirus-based therapeutic cancer vaccine against human papillomavirus (HPV)-induced cancers was performed assessing immunological activity, safety, and tolerability. Vvax001 consists of replication-inc
Autor:
Coba J. van Zanten, Annelies Jorritsma-Smit, Janneke M. Meulenberg, Jolande Schoemaker, Toos Daemen, Daan J Touw, Hans W. Nijman, Jos G. W. Kosterink, Derk P. Allersma
Publikováno v:
European Journal of Pharmaceutical Sciences, 143:105096. ELSEVIER SCIENCE BV
Therapeutic vaccination is being explored as a treatment strategy for the treatment of patients with primary or metastatic tumours. We developed a vaccine targeted to Human papillomavirus (HPV)-induced tumours based on recombinant Semliki Forest viru
Autor:
Guoqing Liu, Michael R. Hayden, Jan Albert Kuivenhoven, Wim T. J. M. C. Hermens, Janneke M. Meulenberg, Jaap Twisk, Karin van den Oever, Jaap Rip, John J.P. Kastelein, Colin J. D. Ross, Ewoud Moraal
Publikováno v:
Human Gene Therapy. 15:906-919
Human lipoprotein lipase (LPL) deficiency causes profound hypertriglyceridemia and life-threatening pancreatitis. We recently developed an adult murine model for LPL deficiency: LPL -/- mice display grossly elevated plasma triglyceride (TG) levels (>
Autor:
Annemarie Kleefstra, Sander J. H. van Deventer, Janneke M Meulenberg, Shyrie Edmonson, Federico Mingozzi, Katherine A. High, Daniel J. Hui, Daniel Gaudet, Denise Morin
Publikováno v:
Blood. 112:822-822
Administration of adeno-associated viral vectors (AAV) has resulted in long-term therapeutic gene transfer in multiple large animal models of disease, but attempts to translate systemic administration of AAV to humans have been limited in some cases
Autor:
Colin J. D. Ross, Michael R. Hayden, Paul A. Dijkhuizen, Janneke M. Meulenberg, John J.P. Kastelein, Jaap Rip, Wim T. J. M. C. Hermens, Andrew C. Bakker, Fudan Miao, Dennis Verbart, Jaap Twisk, Jan Albert Kuivenhoven, Tamara Godbey
Publikováno v:
Human gene therapy, 17(5), 487-499. Mary Ann Liebert Inc.
Human lipoprotein lipase (hLPL) deficiency, for which there currently exists no adequate treatment, leads to excessive plasma triglycerides (TGs), recurrent abdominal pain, and life-threatening pancreatitis. We have shown that a single intramuscular
Autor:
J.J.P. Kastelein, A.C. Bakker, Janneke M. Meulenberg, P. Dijkhuizen, Jan Albert Kuivenhoven, Jaap Twisk, Jaap Rip, Melchior C. Nierman, Erik S.G. Stroes, W.T. Hermens, Michael R. Hayden, C.J.D. Ross
Publikováno v:
Atherosclerosis Supplements. 7:19
Autor:
Janneke M. Meulenberg, Karin van den Oever, Erik S.G. Stroes, Melchior C. Nierman, John J.P. Kastelein, Jaap Twisk, Michael R. Hayden, Colin J. D. Ross, Wim T. J. M. C. Hermens, Jeroen A. Sierts, Andrew C. Bakker, Jaap Rip, Daniël H. van Raalte, Jan Albert Kuivenhoven, Paul A. Dijkhuizen, Wilma Petersen
Publikováno v:
Human gene therapy, 16(11), 1276-1286. Mary Ann Liebert Inc.
Lipoprotein lipase (LPL) deficiency causes hypertriglyceridemia and recurrent, potentially life- threatening pancreatitis. There currently is no adequate treatment for this disease. Previously, we showed that intramuscular administration of an adeno-
Autor:
John J.P. Kastelein, Albertine de Jong, Janneke M. Meulenberg, Melchior C. Nierman, Jaap Rip, Jan Albert Kuivenhoven, Jeroen A. Sierts, Jaap Twisk, Paul A. Dijkhuizen, Michael R. Hayden, Wim T. J. M. C. Hermens, Colin J. D. Ross
Publikováno v:
Molecular Therapy. 11:S351
Lipoprotein lipase (LPL) deficiency cannot be effectively treated and causes severe hypertriglyceridemia and pancreatitis. We have reported that adeno-associated virus serotype 1 (AAV1) based gene therapy normalizes triglyceride levels in LPL deficie
Autor:
Yvonne Mijnsbergen, Wim T. J. M. C. Hermens, Dennis Verbart, Pim Hermans, Jaap Twisk, Paul A. Dijkhuizen, Paul P. A. Oranje, Peter Verheesen, Janneke M. Meulenberg, Mark R. ten Haaft, Hans J. W. Haard
Publikováno v:
Molecular Therapy. 9:S162
Recombinant adeno-associated virus (rAAV) vectors hold promise for human gene therapy. Although most preclinical studies and current phase I clinical trials use vectors derived from rAAV serotype 2, other serotypes have been identified which transduc
Autor:
Michael R. Hayden, Janneke M. Meulenberg, Andrew C. Bakker, Maarten Beetz, Dennis Verbart, Jaap Twisk, John J.P. Kastelein, Fudan Miao, Colin J. D. Ross, Guoqing Liu, Karen van den Oever, Paul A. Dijkhuizen, Jan Albert Kuivenhoven, Paul P. A. Oranje, Wim T. J. M. C. Hermens
Publikováno v:
Molecular Therapy. 9:S17
Lipoprotein lipase (LPL) deficiency is characterized by excessive plasma triglyceride levels (TG), resulting in visibly milky plasma and severe clinical symptoms including life-threatening pancreatitis. There is no treatment for this inherited metabo