Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janneke G C Peeters"'
Autor:
Michiel van Gent, Steven G E Braem, Annemieke de Jong, Nezira Delagic, Janneke G C Peeters, Ingrid G J Boer, Paul N Moynagh, Elisabeth Kremmer, Emmanuel J Wiertz, Huib Ovaa, Bryan D Griffin, Maaike E Ressing
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003960 (2014)
Viral infection triggers an early host response through activation of pattern recognition receptors, including Toll-like receptors (TLR). TLR signaling cascades induce production of type I interferons and proinflammatory cytokines involved in establi
Externí odkaz:
https://doaj.org/article/7a3f141db34946119f8c45c72780d9fc
Autor:
Irene Wuethrich, Janneke G C Peeters, Annet E M Blom, Christopher S Theile, Zeyang Li, Eric Spooner, Hidde L Ploegh, Carla P Guimaraes
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109883 (2014)
Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a
Externí odkaz:
https://doaj.org/article/e7c5298442ba4a569a0e3bf5e40dec51
Autor:
Janneke G C Peeters, Arjan Boltjes, Rianne C Scholman, Stephin J Vervoort, Paul J Coffer, Michal Mokry, Sebastiaan J Vastert, Femke van Wijk, Jorg van Loosdregt
Publikováno v:
Rheumatology.
Objectives How the local inflammatory environment regulates epigenetic changes in the context of inflammatory arthritis remains unclear. Here we assessed the transcriptional and active enhancer profile of monocytes derived from the inflamed joints of
Autor:
Ceri A. Roberts, Femke van Wijk, Veerle Fleskens, Sytze de Roock, Mark Wekking, Sebastiaan J. Vastert, Marthe Knijff, Gerdien Mijnheer, Weiyang Tao, Janneke G. C. Peeters, Leonie S. Taams, Lisanne Lutter, Michal Mokry, Rianne C. Scholman, Marlot van der Wal, Jorg van Loosdregt, Stephin J. Vervoort, Aridaman Pandit, Alessandra Petrelli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Treg cells are critical regulators of immune homeostasis, and environment-driven Treg cell differentiation into effector (e)Treg cells is crucial for optimal functioning. However, human Treg cell programming in inflammation is unclear. Here, we combi
Autor:
Janneke G C, Peeters, Michel, DuPage
Publikováno v:
Nature cancer. 2(10)
Autor:
Michel DuPage, Janneke G. C. Peeters
Publikováno v:
Nature Cancer. 2:996-997
Shedding light on epigenetic mechanisms controlling anti-tumor immune responses, a new study shows that the tumor-intrinsic ring finger protein 2 (RNF2), the catalytic subunit of Polycomb repressor complex 1 (PRC1), acts as a negative regulator of a
Autor:
Marthe Knijff, Marlot van der Wal, Janneke G. C. Peeters, Leonie S. Taams, Jorg van Loosdregt, Sytze de Roock, Mark Wekking, Femke van Wijk, Rianne C. Scholman, Aridaman Pandit, Michal Mokry, Weiyang Tao, Gerdien Mijnheer, Ceri A. Roberts, Stephin J. Vervoort, Alessandra Petrelli, Lisanne Lutter, Sebastiaan J. Vastert, Veerle Fleskens
Treg are critical regulators of immune homeostasis, and increasing evidence demonstrates that environment-driven Treg differentiation into effector (e)Treg is crucial for optimal functioning. However, human Treg programming under inflammatory conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad188c894f2ff2dde81ac509426a615
https://doi.org/10.1101/2020.09.30.319962
https://doi.org/10.1101/2020.09.30.319962
Autor:
Fulvio Reggiori, Mario Mauthe, Janneke G. C. Peeters, J van Loosdregt, E Mocholi, Stephin J. Vervoort, Michal Mokry, C. de Heus, SJ Vastert, S G J M Coenen, L W Picavet, Judith Klumperman, P. J. Coffer
Publikováno v:
Autophagy
Autophagy, 15(1), 98. Landes Bioscience
Autophagy, 15(1), 98-112. Taylor & Francis Group
Autophagy, 15(1), 98. Landes Bioscience
Autophagy, 15(1), 98-112. Taylor & Francis Group
Macroautophagy (hereafter autophagy) is a lysosomal degradation pathway critical for maintaining cellular homeostasis and viability, and is predominantly regarded as a rapid and dynamic cytoplasmic process. To increase our understanding of the transc
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 10(FEB). Frontiers Media S. A.
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 10(FEB). Frontiers Media S. A.
Frontiers in Immunology, Vol 10 (2019)
Juvenile Idiopathic Arthritis (JIA) is characterized by a loss of immune tolerance. Here, the balance between the activity of effector T (Teff) cells and regulatory T (Treg) cells is disturbed resulting in chronic inflammation in the joints. Presentl
Autor:
Alejandra Bruna, Carlos Caldas, Cynthia L Frederiks, Stephin J. Vervoort, José Luis Sandoval, Cornelieke Pals, Oscar M. Rueda, Ana Tufegdzic Vidakovic, Janneke G. C. Peeters, Ana Rita Lourenço, Enric Mocholi, Paul J. Coffer
Publikováno v:
Nucleic Acids Research, 46(18), 9578. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research
Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disease outcome. Reduction of SOX4 expression results in both diminished tumor-incidence and metastasis. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe4d6567d8d50aab4a23c0fc0557a76
https://www.repository.cam.ac.uk/handle/1810/286942
https://www.repository.cam.ac.uk/handle/1810/286942