Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janneke G C, Peeters"'
Autor:
Gerdien Mijnheer, Lisanne Lutter, Michal Mokry, Marlot van der Wal, Rianne Scholman, Veerle Fleskens, Aridaman Pandit, Weiyang Tao, Mark Wekking, Stephin Vervoort, Ceri Roberts, Alessandra Petrelli, Janneke G. C. Peeters, Marthe Knijff, Sytze de Roock, Sebastiaan Vastert, Leonie S. Taams, Jorg van Loosdregt, Femke van Wijk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
T regulatory (Treg) cells can differentiate into effector Treg (eTreg) cells that might be functional in inflammatory diseases. Using RNA sequencing and epigenetic profiling, the authors show that eTreg signatures in juvenile idiopathic arthritis joi
Externí odkaz:
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Juvenile Idiopathic Arthritis (JIA) is characterized by a loss of immune tolerance. Here, the balance between the activity of effector T (Teff) cells and regulatory T (Treg) cells is disturbed resulting in chronic inflammation in the joints. Presentl
Externí odkaz:
https://doaj.org/article/1133866446904d0782fb5bf6c62c8e76
Autor:
Janneke G C Peeters, Arjan Boltjes, Rianne C Scholman, Stephin J Vervoort, Paul J Coffer, Michal Mokry, Sebastiaan J Vastert, Femke van Wijk, Jorg van Loosdregt
Publikováno v:
Rheumatology.
Objectives How the local inflammatory environment regulates epigenetic changes in the context of inflammatory arthritis remains unclear. Here we assessed the transcriptional and active enhancer profile of monocytes derived from the inflamed joints of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd0a262e821b0032473563c086139ad
https://doi.org/10.1093/rheumatology/kead001
https://doi.org/10.1093/rheumatology/kead001
Autor:
Ceri A. Roberts, Femke van Wijk, Veerle Fleskens, Sytze de Roock, Mark Wekking, Sebastiaan J. Vastert, Marthe Knijff, Gerdien Mijnheer, Weiyang Tao, Janneke G. C. Peeters, Leonie S. Taams, Lisanne Lutter, Michal Mokry, Rianne C. Scholman, Marlot van der Wal, Jorg van Loosdregt, Stephin J. Vervoort, Aridaman Pandit, Alessandra Petrelli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Treg cells are critical regulators of immune homeostasis, and environment-driven Treg cell differentiation into effector (e)Treg cells is crucial for optimal functioning. However, human Treg cell programming in inflammation is unclear. Here, we combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f0f87cba9d9bb49145a7d186ed6c2
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
Autor:
Janneke G C, Peeters, Michel, DuPage
Publikováno v:
Nature cancer. 2(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76cac461839c55ff0b8895df9a6ff2b8
https://pubmed.ncbi.nlm.nih.gov/35121884
https://pubmed.ncbi.nlm.nih.gov/35121884
Autor:
Michiel van Gent, Steven G E Braem, Annemieke de Jong, Nezira Delagic, Janneke G C Peeters, Ingrid G J Boer, Paul N Moynagh, Elisabeth Kremmer, Emmanuel J Wiertz, Huib Ovaa, Bryan D Griffin, Maaike E Ressing
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003960 (2014)
Viral infection triggers an early host response through activation of pattern recognition receptors, including Toll-like receptors (TLR). TLR signaling cascades induce production of type I interferons and proinflammatory cytokines involved in establi
Externí odkaz:
https://doaj.org/article/7a3f141db34946119f8c45c72780d9fc
Autor:
Irene Wuethrich, Janneke G C Peeters, Annet E M Blom, Christopher S Theile, Zeyang Li, Eric Spooner, Hidde L Ploegh, Carla P Guimaraes
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109883 (2014)
Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a
Externí odkaz:
https://doaj.org/article/e7c5298442ba4a569a0e3bf5e40dec51
Autor:
Michel DuPage, Janneke G. C. Peeters
Publikováno v:
Nature Cancer. 2:996-997
Shedding light on epigenetic mechanisms controlling anti-tumor immune responses, a new study shows that the tumor-intrinsic ring finger protein 2 (RNF2), the catalytic subunit of Polycomb repressor complex 1 (PRC1), acts as a negative regulator of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccbeef4efec2b987f946e9460d3045c2
https://doi.org/10.1038/s43018-021-00270-0
https://doi.org/10.1038/s43018-021-00270-0
Autor:
Marthe Knijff, Marlot van der Wal, Janneke G. C. Peeters, Leonie S. Taams, Jorg van Loosdregt, Sytze de Roock, Mark Wekking, Femke van Wijk, Rianne C. Scholman, Aridaman Pandit, Michal Mokry, Weiyang Tao, Gerdien Mijnheer, Ceri A. Roberts, Stephin J. Vervoort, Alessandra Petrelli, Lisanne Lutter, Sebastiaan J. Vastert, Veerle Fleskens
Treg are critical regulators of immune homeostasis, and increasing evidence demonstrates that environment-driven Treg differentiation into effector (e)Treg is crucial for optimal functioning. However, human Treg programming under inflammatory conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad188c894f2ff2dde81ac509426a615
https://doi.org/10.1101/2020.09.30.319962
https://doi.org/10.1101/2020.09.30.319962
Autor:
Fulvio Reggiori, Mario Mauthe, Janneke G. C. Peeters, J van Loosdregt, E Mocholi, Stephin J. Vervoort, Michal Mokry, C. de Heus, SJ Vastert, S G J M Coenen, L W Picavet, Judith Klumperman, P. J. Coffer
Publikováno v:
Autophagy
Autophagy, 15(1), 98. Landes Bioscience
Autophagy, 15(1), 98-112. Taylor & Francis Group
Autophagy, 15(1), 98. Landes Bioscience
Autophagy, 15(1), 98-112. Taylor & Francis Group
Macroautophagy (hereafter autophagy) is a lysosomal degradation pathway critical for maintaining cellular homeostasis and viability, and is predominantly regarded as a rapid and dynamic cytoplasmic process. To increase our understanding of the transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb229f3ab33de8974cb35ec884754529
http://europepmc.org/articles/PMC6287694
http://europepmc.org/articles/PMC6287694