Výsledky vyhledávání

Harmonic analysis of surface instability patterns on colloidal particles

Autor: Jani Seitsonen, Esko I. Kauppinen, Tero Kämäräinen, Janne Raula, Janne Ruokolainen, Mariko Ago, Orlando J. Rojas

Publikováno v: Soft matter. 14(17)

Wrinkling of colloidal particles alter a wide variety of interfacial properties but quantitative topographical descriptions have been explored experimentally to a very limited extent. In this study, we present a harmonic analysis of surface wrinkles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48d699292ab09d11a0cee2ec7a49b84
https://pubmed.ncbi.nlm.nih.gov/29666871

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Multistage pH-responsive mucoadhesive nanocarriers prepared by aerosol flow reactor technology: A controlled dual protein-drug delivery system

Autor: Janne Raula, Bruno Sarmento, Jouni Hirvonen, Francisca Araújo, Jarno Salonen, Esko I. Kauppinen, Hélder A. Santos, Ermei Mäkilä, Neha Shrestha, Mohammad-Ali Shahbazi

Publikováno v: Biomaterials. 68:9-20

Nanotechnology based drug delivery systems are anticipated to overcome the persistent challenges in oral protein and peptide administration, and lead to the development of long awaited non-invasive therapies. Herein, an advanced single-step aerosol f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b7bd54883e6524d7dd6923badaefb1
https://doi.org/10.1016/j.biomaterials.2015.07.045

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Functionalization of Alkyne-Terminated Thermally Hydrocarbonized Porous Silicon Nanoparticles With Targeting Peptides and Antifouling Polymers: Effect on the Human Plasma Protein Adsorption

Autor: Chang-Fang Wang, Jarno Salonen, Jussi Rytkönen, Janne Raula, Sérgio Frascino Müller de Almeida, Ale Närvänen, Sébastien Lecommandoux, Errnei M. Makila, Hélder A. Santos, Colin Bonduelle, Jouni Hirvonen

Publikováno v: ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2015, 7 (3), pp.2006-2015. ⟨10.1021/am507827n⟩

International audience; Porous silicon (PSi) nanomaterials combine a high drug loading capacity and tunable surface chemistry with various surface modifications to meet the requirements for biomedical applications. In this work, alkyne-terminated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f037c54ae7e9577df06c9f67d7ba8d

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Synthesis and lectin recognition of glycosylated amphiphilic nanoparticles

Autor: Sami Hietala, Lauri Valtola, Heikki Tenhu, Antti Rahikkala, Esko I. Kauppinen, Janne Raula

Publikováno v: European Polymer Journal. 59:282-289

Carbohydrate–protein interactions play an important role in many biomolecular recognition events and thus artificial glycopolymers and glycoparticles are actively developed. Nanoprecipitation and aerosol flow reactor techniques were used to prepare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15e8dc920425aebae5c3649f6cd6203e
https://doi.org/10.1016/j.eurpolymj.2014.07.031

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Injected nanoparticles: The Combination of Experimental Systems to Assess Cardiovascular Adverse Effects

Autor: Olga S. Tarasova, Anatoly S. Lobach, Jarno Salonen, Kristiina Järvinen, M. A. Vlasova, Karl-Heinz Herzig, Janne Raula, Vesa-Pekka Lehto, Alexander V. Eletskii, Esko I. Kauppinen, Smirin Bv, Joakim Riikonen, A. A. Borzykh, Pasi Tavi

Publikováno v: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 87(1):64-72

When nanocarriers are used for drug delivery they can often achieve superior therapeutic outcomes over standard drug formulations. However, concerns about their adverse effects are growing due to the association between exposure to certain nanosized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaa883f1bbd331582cc6828c5537e6a
https://doi.org/10.1016/j.ejpb.2014.02.001

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Reinforcing randomly oriented transparent freestanding single-walled carbon nanotube films

Autor: Kestutis Grigoras, Esko I. Kauppinen, Kimmo Mustonen, Marko Kauppinen, Hua Jiang, Albert G. Nasibulin, Janne Raula, Marko Pudas

Publikováno v: Carbon. 62:513-516

We report an improvement of the mechanical properties of transparent randomly oriented freestanding single-walled carbon nanotube (SWCNT) films by deposition of polymers using a drop casting method and aluminum oxide utilizing an atomic layer deposit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ba40b5cdaedca5f22a2d7f379778afb
https://doi.org/10.1016/j.carbon.2013.05.072

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Self-assembly of PS-b-P4VP block copolymers of varying architectures in aerosol nanospheres

Autor: Raffaele Mezzenga, Antti J. Soininen, Antti Rahikkala, Janne Ruokolainen, Janne Raula, Esko I. Kauppinen

Publikováno v: Soft Matter. 9:1492-1499

Poly(styrene-block-4-vinylpyridine) (PS-b-P4VP) nanospheres are prepared in an aerosol phase where the self-assembly is induced by initial solvent evaporation and subsequent thermal annealing. The block copolymers self-assemble into different structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07be225d2a6a32f37223a3a80d0988e5
https://doi.org/10.1039/c2sm26913a

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P115 Inhalable drug formulations for Idiopathic Pulmonary Fiborsis

Autor: Esko I. Kauppinen, Amanda Attobrah, Katri Koli, Marjukka Myllärniemi, Ville Vartiainen, Janne Raula

Publikováno v: QJM: An International Journal of Medicine.

Idiopathic pulmonary fibrosis (IPF) is a severe progressive fibrotic lung disease. During the past few years two orally administered drug candidates (pirfenidone and nintedanib) for slowing the progression of IPF were approved for clinical practice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80a82aa1ce00662d3a27e10859dc5e89
https://doi.org/10.1093/qjmed/hcw120.016

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