Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janne Mäkinen"'
Autor:
Mehdi Taebnia, Marko Heikkilä, Janne Mäkinen, Jenni Kiukkonen-Kivioja, Jouko Pakanen, Jarek Kurnitski
Publikováno v:
Energies, Vol 13, Iss 6, p 1401 (2020)
Nowadays, many buildings are equipped with various energy sources. The challenge is how to efficiently utilize their energy production. This includes decreasing the share and costs of external energy—usually electrical energy delivered from the gri
Externí odkaz:
https://doaj.org/article/80c7b753eab14194b8066ddcd15620a3
Autor:
Jouko Pakanen, Jarek Kurnitski, Jenni Kiukkonen-Kivioja, Janne Mäkinen, Marko Heikkilä, Mehdi Taebnia
Publikováno v:
Energies, Vol 13, Iss 6, p 1401 (2020)
Energies; Volume 13; Issue 6; Pages: 1401
Energies; Volume 13; Issue 6; Pages: 1401
Nowadays, many buildings are equipped with various energy sources. The challenge is how to efficiently utilize their energy production. This includes decreasing the share and costs of external energy—usually electrical energy delivered from the gri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2949db09a72871eeb9328b75a3979f59
https://aaltodoc.aalto.fi/handle/123456789/43693
https://aaltodoc.aalto.fi/handle/123456789/43693
Autor:
Johanna Jyrkkärinne, Björn Windshügel, Wolfgang Sippl, Markku Ylisirniö, Mikael Peräkylä, Paavo Honkakoski, Janne Mäkinen, Antti Poso
Publikováno v:
The Journal of biological chemistry. 280(7)
The human constitutive androstane receptor (CAR, NR1I3) is an important ligand-activated regulator of oxidative and conjugative enzymes and transport proteins. Because of the lack of a crystal structure of the ligand-binding domain (LBD), wide specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6688acee69821b7b0f6ad22519cb69
https://pubmed.ncbi.nlm.nih.gov/15572376
https://pubmed.ncbi.nlm.nih.gov/15572376
Autor:
Paavo Honkakoski, Mika Reinisalo, Johanna Jyrkkärinne, Olavi Pelkonen, Hinfan Chung, Kaisa Niemi, Janne Mäkinen, Pirkko Viitala
mCAR (mouse constitutive androstane receptor; NR1I3) controls the expression of cytochrome P450 as well as other enzymes involved in drug and steroid metabolism. The high basal activity of mCAR can be modulated by inhibitory steroids related to andro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b6ac4eb38749a87297b34ab8b33766
https://europepmc.org/articles/PMC1223782/
https://europepmc.org/articles/PMC1223782/
Autor:
Paavo Honkakoski, Jukka Gynther, Heidi Savolainen, Janne Mäkinen, Johanna Jyrkkärinne, and Antti Poso
Publikováno v:
Journal of medicinal chemistry. 46(22)
The constitutive androstane receptor (CAR) regulates drug and steroid metabolism through binding to cytochrome P450 2B, 2C, and 3A gene enhancers. Uniquely among nuclear receptors, mouse CAR (mCAR) can be suppressed by androstenol and activated by st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b01fe49b3610d9a95d08d5c3a16b0f
https://pubmed.ncbi.nlm.nih.gov/14561088
https://pubmed.ncbi.nlm.nih.gov/14561088
Autor:
Janne Mäkinen, Christian Frank, Paavo Honkakoski, Jukka Gynther, Johanna Jyrkkärinne, Carsten Carlberg
Publikováno v:
Molecular pharmacology. 62(2)
The constitutive androstane receptor (CAR) regulates mouse and human CYP2B genes through binding to the direct repeat-4 (DR4) motifs present in the phenobarbital-responsive enhancer module (PBREM). The preference of PBREM elements for nuclear recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0913e0fe2da2f739667db46f7a8242
https://pubmed.ncbi.nlm.nih.gov/12130690
https://pubmed.ncbi.nlm.nih.gov/12130690
Publikováno v:
American Journal of Pharmaceutical Education. 69:26
Objectives. Nuclear receptors (NRs) are ligand-activated transcription factors that regulate development and cellular differentiation, endocrine functions, and metabolism and transport of nutrients and drugs. Understanding of NR action is therefore e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af411c1af5f4a4e6d3f6c711bc5b3b28
https://doi.org/10.5688/aj690226
https://doi.org/10.5688/aj690226