Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janna N, Hauser"'
Autor:
Christoph J Slavetinsky, Janna N Hauser, Cordula Gekeler, Jessica Slavetinsky, André Geyer, Alexandra Kraus, Doris Heilingbrunner, Samuel Wagner, Michael Tesar, Bernhard Krismer, Sebastian Kuhn, Christoph M Ernst, Andreas Peschel
Publikováno v:
eLife, Vol 11 (2022)
The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases
Externí odkaz:
https://doaj.org/article/cf8b010f11b840a988723d76c0335377
Autor:
Christoph M. Ernst, Christoph J. Slavetinsky, Sebastian Kuhn, Janna N. Hauser, Mulugeta Nega, Nagendra N. Mishra, Cordula Gekeler, Arnold S. Bayer, Andreas Peschel
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Daptomycin, a calcium-dependent lipopeptide antibiotic whose full mode of action is still not entirely understood, has become a standard-of-care agent for treating methicillin-resistant Staphylococcus aureus (MRSA) infections. Daptomycin-res
Externí odkaz:
https://doaj.org/article/91185988fd2b4f0eadcc6a36be94023e
Autor:
Janna N. Hauser, Arnaud Kengmo Tchoupa, Susanne Zabel, Kay Nieselt, Christoph M. Ernst, Christoph J. Slavetinsky, Andreas Peschel
Flippase proteins exchanging phospholipids between the cytoplasmic membrane leaflets have been identified in Eukaryotes but remained largely unknown in Prokaryotes. Only MprF proteins that synthesize aminoacyl phospholipids in some bacteria have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba116a00f30bcf3e7d5e4b9fe1acfe5
https://doi.org/10.1101/2022.03.11.483950
https://doi.org/10.1101/2022.03.11.483950
Autor:
Christoph J Slavetinsky, Janna N Hauser, Cordula Gekeler, Jessica Slavetinsky, André Geyer, Alexandra Kraus, Doris Heilingbrunner, Samuel Wagner, Michael Tesar, Bernhard Krismer, Sebastian Kuhn, Christoph M Ernst, Andreas Peschel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08d969051cd31bcbef0a52657573a27
https://doi.org/10.7554/elife.66376.sa2
https://doi.org/10.7554/elife.66376.sa2
Autor:
Christoph J, Slavetinsky, Janna N, Hauser, Cordula, Gekeler, Jessica, Slavetinsky, André, Geyer, Alexandra, Kraus, Doris, Heilingbrunner, Samuel, Wagner, Michael, Tesar, Bernhard, Krismer, Sebastian, Kuhn, Christoph M, Ernst, Andreas, Peschel
Publikováno v:
eLife
The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea6f53dcf907c4838c5d5bede5346697
https://pubmed.ncbi.nlm.nih.gov/35044295
https://pubmed.ncbi.nlm.nih.gov/35044295
Autor:
Janna N. Hauser, Alexandra Kraus, Cordula Gekeler, Sebastian Kuhn, Samuel Wagner, Bernhard Krismer, Doris Heilingbrunner, Michael Tesar, Christoph Slavetinsky, Christoph M. Ernst, André Geyer, Jessica Slavetinsky, Andreas Peschel
The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. MprF is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases virulence and resistance of methicill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d166399f8ca52c7c13bee5c6fd61d3c
https://doi.org/10.1101/2020.11.12.379776
https://doi.org/10.1101/2020.11.12.379776
Autor:
Nagendra N. Mishra, Arnold S. Bayer, Andreas Peschel, Janna N. Hauser, Christoph M. Ernst, Sebastian Kuhn, Christoph Slavetinsky, Mulugeta Nega, Cordula Gekeler
Publikováno v:
mBio
mBio, Vol 9, Iss 6, p e01659-18 (2018)
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e01659-18 (2018)
mBio, Vol 9, Iss 6 (2018)
Ever since daptomycin was introduced to the clinic, daptomycin-resistant isolates have been reported. In most cases, the resistant isolates harbor point mutations in MprF, which produces and flips the positively charged phospholipid LysPG. This has l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5043460dc1a16b1d43a885136c097c
http://europepmc.org/articles/PMC6299216
http://europepmc.org/articles/PMC6299216