Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Janna E. Quinn"'
Publikováno v:
Prostate Cancer and Prostatic Diseases. 8:253-259
Zoledronic acid (ZA) has been shown to inhibit prostate tumor growth in vitro and have beneficial effects in patients with advanced prostate cancer (CaP). The aim of this study was to determine whether ZA exhibits direct anti-tumor effects on CaP cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f336f693b483035480f949bbe2fcdd2
https://doi.org/10.1038/sj.pcan.4500815
https://doi.org/10.1038/sj.pcan.4500815
Autor:
Janna E. Quinn, Evan T. Keller, Austin M. Odman, Robert L. Vessella, Paul J. Kostenuik, Jeff Kiefer, Colin R. Dunstan, Eva Corey, Jian Zhang
Publikováno v:
Clinical & Experimental Metastasis. 21:381-387
Osteoprotegerin (OPG) plays a central role in controlling bone resorption. Exogenous administration of OPG has been shown to be effective in preventing osteolysis and limiting the growth of osteolytic metastasis. The objective of this study was to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b35837feec99610a0836a2e2ba0c79d
https://doi.org/10.1007/s10585-004-2869-0
https://doi.org/10.1007/s10585-004-2869-0
Autor:
Janna E. Quinn, B. B. Kegley, Robert L. Vessella, Ming Kuan Chyan, D. Scott Wilbur, Donald K. Hamlin
Publikováno v:
Bioconjugate Chemistry. 15:601-616
An investigation has been conducted to prepare and evaluate several radiohalogenated biotin derivatives as part of our studies to develop reagents for carrying 2 1 1 At in cancer pretargeting protocols. The primary goal of the investigation was to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081b5a0a56adddf32635ab69c01e05ac
https://doi.org/10.1021/bc034229q
https://doi.org/10.1021/bc034229q
Autor:
Sabine Kral, Carrie M. Sorensen, Arie S. Belldegrun, Janna E. Quinn, Kristen D. Brubaker, Alvin Y. Liu, Young Ah Goo, Robert L. Vessella, Leroy Hood
Publikováno v:
The Prostate. 60:98-108
BACKGROUND LNCaP and its derivative cell lines, which include C4-2 (and the related C4-2B) and CL1, are used as models of prostate cancer. Unlike LNCaP, the other cell lines show features of progressed disease such as metastatic capability and hormon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2872148523dceed133e3d77273f85901
https://doi.org/10.1002/pros.20031
https://doi.org/10.1002/pros.20031
Autor:
Robert L. Vessella, Janna E. Quinn, Jian Zhang, Austin M. Odman, Eva Corey, Evan T. Keller, Jesco Pfitzenmaier
Publikováno v:
Journal of Bone and Mineral Research. 18:1882-1888
New well-characterized preclinical models of prostate cancer (CaP) bone metastases are needed to improve our understanding of the development of CaP-related bone disease in patients. Here we describe characterization of a model consisting of direct i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbd2285f267324e59b4354ca3c8f7bb
https://doi.org/10.1359/jbmr.2003.18.10.1882
https://doi.org/10.1359/jbmr.2003.18.10.1882
Publikováno v:
The Prostate. 56:110-114
BACKGROUND Spontaneous metastasis following implantation at the orthotopic site is a highly desired feature in prostate cancer (CaP) models, since it would enable studies of mechanisms associated with tumor cell dissemination. METHODS LuCaP 23.8 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f37e34e5b858b8bb67d509871fb8b3
https://doi.org/10.1002/pros.10235
https://doi.org/10.1002/pros.10235
Autor:
Robert L. Vessella, Eva Corey, Lawrence D. True, Peter S. Nelson, Jill A. Macoska, Janna E. Quinn, Kent R. Buhler
Publikováno v:
The Prostate. 55:239-246
Background Generation of suitable in vivo models is critical for understanding of processes associated with development and progression of prostate cancer (CaP). Methods Lymph nodes containing metastatic androgen-independent CaP were implanted into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d446c57d68e649c7a1c80d57a8c02f
https://doi.org/10.1002/pros.10198
https://doi.org/10.1002/pros.10198
Autor:
Robert L. Vessella, Lawrence D. True, Peter S. Nelson, Alec Moorman, Hugh Arnold, Janna E. Quinn, Camari Ferguson, Nigel Clegg
Publikováno v:
The Prostate. 55:55-64
OBJECTIVES. A subset of prostate carcinomas is composed predominantly, even exclusively, of neuroendocrine (NE) cells. In this report, we sought to characterize the gene expression profile of a prostate small cell NE carcinoma by assessing the divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8356f0bfbc6cfba56c60c1db8d1040
https://doi.org/10.1002/pros.10217
https://doi.org/10.1002/pros.10217
Autor:
Janna E. Quinn, Robert L. Vessella, Thomas H. Norwood, Kent R. Buhler, Nigel Clegg, William J. Ellis, Lawrence D. True, Peter S. Nelson, Jill A. Macoska, Alvin Y. Liu, Paul H. Lange, Emily C. Williams
Publikováno v:
The American Journal of Pathology. 161:705-715
The late stages of progression of prostate carcinoma are typically characterized by an androgen-insensitive, rapidly proliferative state. Some late-stage tumors are composed predominantly of neuroendocrine cells. Virtually no animal models of a neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c42c40972ac55b755c556abf4c853b
https://doi.org/10.1016/s0002-9440(10)64226-5
https://doi.org/10.1016/s0002-9440(10)64226-5
Autor:
Julie M. Brown, Janna E. Quinn, Eva Corey, Franck Bladou, Lisha G. Brown, Martine Roudier, Robert L. Vessella, Kent R. Buhler
Publikováno v:
The Prostate. 52:20-33
BACKGROUND To improve the therapy of advanced prostate cancer (CaP), it is critical to develop animal models that mimic CaP bone metastases. Unlike the human disease, CaP xenograft models rarely metastasize spontaneously to bone from the orthotopic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98679679d4c379ede576927844e6fbe2
https://doi.org/10.1002/pros.10091
https://doi.org/10.1002/pros.10091