Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janna Bednenko"'
Publikováno v:
Handbook of experimental pharmacology. 267
Monoclonal antibodies combine specificity and high affinity binding with excellent pharmacokinetic properties and are rapidly being developed for a wide range of drug targets including clinically important potassium ion channels. Nonetheless, while t
Publikováno v:
Pharmacology of Potassium Channels ISBN: 9783030840518
Monoclonal antibodies combine specificity and high affinity binding with excellent pharmacokinetic properties and are rapidly being developed for a wide range of drug targets including clinically important potassium ion channels. Nonetheless, while t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4b00b94e458670d42c7c95a192e0e4
https://doi.org/10.1007/164_2021_464
https://doi.org/10.1007/164_2021_464
Autor:
Raymond S. Norton, Michael W. Pennington, Paul A. Colussi, Pragalath Sadasivam, Peng Wen Tan, Serdar Kuyucak, Zhong Zhuang, Bankala Krishnarjuna, Abbas El Sahili, Sabina Yasmin, Xuan Rui Ng, Rahul Patil, Christine Beeton, Edward G. Robins, Saumya Bajaj, Mark R. Tanner, Vikas Dhawan, Dahai Luo, Ming Wei Chen, Dharmeshkumar Patel, Hai M. Nguyen, Julien Lescar, Jeremy Jun Heng Ng, Heike Wulff, Rodrigo A.V. Morales, Boominathan Ramasamy, Julian L. Goggi, Janna Bednenko, Shih Chieh Chang, Seow Theng Ong, Siddana V. Hartimath, K. George Chandy, Susan A. Charman
Publikováno v:
ACS pharmacology & translational science, vol 3, iss 4
ACS Pharmacol Transl Sci
ACS Pharmacol Transl Sci
[Image: see text] We describe a cysteine-rich, membrane-penetrating, joint-targeting, and remarkably stable peptide, EgK5, that modulates voltage-gated K(V)1.3 potassium channels in T lymphocytes by a distinctive mechanism. EgK5 enters plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca3c71964accabb770840922bbfc4ca
https://escholarship.org/uc/item/8pv9f5gt
https://escholarship.org/uc/item/8pv9f5gt
Autor:
Serdar Kuyucak, Shih Chieh Chang, Dharmeshkumar Patel, Boominathan Ramasamy, George K. Chandy, Xuan Rui Ng, Jeremy Jun Heng Ng, Saumya Bajaj, Janna Bednenko, Rodrigo Av Morales, Seow Theng Ong, Hai M. Nguyen, Julien Lescar, Christine Beeton, Pragalath Sadasivam, Julian L. Goggi, Paul A. Colussi, Susan A. Charman, Rahul Patil, Bankala Krishnarjuna, Sanling Liu, Wen Tan Peng, Yue Zhao, Mark R. Tanner, Heike Wulff, Hartimath Sv, Longhua Zhang, Wei Chen Ming, Sabina Yasmin, Edward G. Robins, Changlin Tian, Vikas Dhawan, Raymond S. Norton, Michael W. Pennington, El Sahili Abbas, Yong Zhang, Dahai Luo
Publikováno v:
SSRN Electronic Journal.
Author(s): Ong, Seow Theng; Liu, Sanling; Bajaj, Saumya; Zhao, Yue; Tanner, Mark R; Chang, Shih Chieh; Zhang, Yong; Krishnarjuna, Bankala; Ng, Xuan Rui; Morales, Rodrigo AV; Ming, Wei Chen; Luo, Dahai; Patel, Dharmeshkumar; Yasmin, Sabina; Ng, Jeremy
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Harriman William Don, Heike Wulff, Yelena Bisharyan, Lore Mariën, Donna Cassidy-Hanley, Ted Clark, Yasmina Noubia Abdiche, Ellen J. Collarini, Janna Bednenko, Bas van der Woning, Paul A. Colussi, Rian Harriman, Hai M. Nguyen, Joanna Cardarelli, Hans de Haard, Alka Agrawal, Ashot Papoyan, Darlene Pedersen
Publikováno v:
mAbs, vol 10, iss 4
Bednenko, J; Harriman, R; Mariën, L; Nguyen, HM; Agrawal, A; Papoyan, A; et al.(2018). A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3. mAbs, 10(4), 636-650. doi: 10.1080/19420862.2018.1445451. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7w1758ws
mAbs
Bednenko, J; Harriman, R; Mariën, L; Nguyen, HM; Agrawal, A; Papoyan, A; et al.(2018). A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3. mAbs, 10(4), 636-650. doi: 10.1080/19420862.2018.1445451. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7w1758ws
mAbs
© 2018 The Author(s). Taylor & Francis Group, LLC. Identifying monoclonal antibodies that block human voltage-gated ion channels (VGICs) is a challenging endeavor exacerbated by difficulties in producing recombinant ion channel proteins in amounts t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df62db04318783348336c7861780f14
https://escholarship.org/uc/item/7w1758ws
https://escholarship.org/uc/item/7w1758ws
Autor:
Ellen J. Collarini, Janna Bednenko, Donna Cassidy-Hanley, Yelena Bisharyan, Paul A. Colussi, Joanna Cardarelli, Lore Mariën, Ted Clark, Bas van der Woning, Ashot Papoyan, Alka Agrawal, Hai M. Nguyen, Rian Harriman, Hans de Haard, Heike Wulff
Publikováno v:
Biophysical Journal. 114:309a
Autor:
Libin Wang, Dorothy E. Shippen, Leigh Anne Hurley, Timothy Shrode, Janna Bednenko, Zemfira N. Karamysheva
Publikováno v:
Cell. 113(5):565-576
The primary function of telomerase is to maintain preexisting telomere tracts. In the ciliate Euplotes crassus, however, telomerase RNP structure and substrate recognition are altered during macronuclear development to facilitate de novo telomere add
Publikováno v:
Traffic. 4:127-135
Nucleocytoplasmic transport is mediated by shuttling receptors that recognize specific signals on protein or RNA cargoes and translocate the cargoes through the nuclear pore complex. Transport receptors appear to move through the nuclear pore complex
Publikováno v:
The Journal of Cell Biology
Previous work has shown that the transport of some small protein cargoes through the nuclear pore complex (NPC) can occur in vitro in the absence of nucleoside triphosphate hydrolysis. We now demonstrate that in the importin α/β and transportin imp