Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jann C. Ang"'
Autor:
Jenna M. Benoit, Jessica A. Breznik, Jann C. Ang, Hina Bhakta, Angela Huynh, Braeden Cowbrough, Barbara Baker, Lauren Heessels, Sumiya Lodhi, Elizabeth Yan, Joycelyne Ewusie, Ishac Nazy, Jonathan Bramson, Matthew S. Miller, Sasha Bernatsky, Maggie J. Larché, Dawn M. E. Bowdish, the SUCCEED Investigator Group
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Understanding the efficacy of SARS-CoV-2 vaccination in people on immunosuppressive drugs, including those with rheumatoid arthritis (RA), is critical for their protection. Vaccine induced protection requires antibodies, CD4+ T cells, and CD
Externí odkaz:
https://doaj.org/article/88cd259bbf784fcba0ab3f6dfb279877
Autor:
Angela Huynh, Donald M. Arnold, James W. Smith, Jane C. Moore, Ali Zhang, Zain Chagla, Bart J. Harvey, Hannah D. Stacey, Jann C. Ang, Rumi Clare, Nikola Ivetic, Vasudhevan T. Chetty, Dawn M. E. Bowdish, Matthew S. Miller, John G. Kelton, Ishac Nazy
Publikováno v:
Viruses, Vol 13, Iss 4, p 697 (2021)
Coronavirus Disease 2019 (COVID-19) is a global pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While detection of SARS-CoV-2 by polymerase chain reaction with reverse transcription (RT-PCR) is currently use
Externí odkaz:
https://doaj.org/article/a734ff3b8b7d46a59159f6a399a2ad97
Autor:
Jiuxing Li, Zijie Zhang, Jimmy Gu, Ryan Amini, Alexandria G. Mansfield, Jianrun Xia, Dawn White, Hannah D. Stacey, Jann C. Ang, Gurpreet Panesar, Alfredo Capretta, Carlos D. M. Filipe, Karen Mossman, Bruno J. Salena, Jonathan B. Gubbay, Cynthia Balion, Leyla Soleymani, Matthew S. Miller, Deborah Yamamura, John D. Brennan, Yingfu Li
Publikováno v:
Journal of the American Chemical Society. 144:23465-23473
Our previously discovered monomeric aptamer for SARS-CoV-2 (MSA52) possesses a universal affinity for COVID-19 spike protein variants but is ultimately limited by its ability to bind only one subunit of the spike protein. The symmetrical shape of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affd2106019271cf5da112035bcaeb55
https://doi.org/10.1021/jacs.2c09870
https://doi.org/10.1021/jacs.2c09870
Autor:
Leyla Soleymani, Bruno J. Salena, Jimmy Gu, Yingfu Li, Karen L. Mossman, Jiuxing Li, John D. Brennan, Zijie Zhang, Dawn White, Matthew S. Miller, Cynthia Balion, Hannah D. Stacey, Deborah Yamamura, Jann C. Ang, Alfredo Capretta, Richa Pandey, Carlos D. M. Filipe, Catherine-Jean Steinberg
Publikováno v:
Angewandte Chemie (International Ed. in English)
We report a simple and rapid saliva‐based SARS‐CoV‐2 antigen test that utilizes a newly developed dimeric DNA aptamer, denoted as DSA1N5, that specifically recognizes the spike proteins of the wildtype virus and its Alpha and Delta variants wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea4fe8a2a33c16c96bba8873f526940
https://doi.org/10.1002/anie.202110819
https://doi.org/10.1002/anie.202110819
Autor:
Zijie Zhang, Jiuxing Li, Jimmy Gu, Ryan Amini, Hannah D. Stacey, Jann C. Ang, Dawn White, Carlos D. M. Filipe, Karen Mossman, Matthew S. Miller, Bruno J. Salena, Deborah Yamamura, Payel Sen, Leyla Soleymani, John D. Brennan, Yingfu Li
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118c67e6490b2fbe5b9c273d179ecba9
https://doi.org/10.1002/chem.202200523
https://doi.org/10.1002/chem.202200523
Autor:
Zijie Zhang, Jiuxing Li, Jimmy Gu, Ryan Amini, Hannah D. Stacey, Jann C. Ang, Dawn White, Carlos D. M. Filipe, Karen Mossman, Matthew S. Miller, Bruno J. Salena, Deborah Yamamura, Payel Sen, Leyla Soleymani, John D. Brennan, Yingfu Li
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(15)
We report on a unique DNA aptamer, denoted MSA52, that displays universally high affinity for the spike proteins of wildtype SARS-CoV-2 as well as the Alpha, Beta, Gamma, Epsilon, Kappa, Delta and Omicron variants. Using an aptamer pool produced from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9168252e940a40b1501212ad0f766f
https://pubmed.ncbi.nlm.nih.gov/35084794
https://pubmed.ncbi.nlm.nih.gov/35084794
Autor:
Michael R. D’Agostino, Jann C. Ang, Matthew S. Miller, Ali Zhang, Yonathan Agung, Hanu Chaudhari
SummaryThe conserved hemagglutinin stalk domain is an attractive target for broadly effective antibody-based therapeutics and next generation universal influenza vaccines. Protection provided by hemagglutinin stalk binding antibodies is principally m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218b94dbdeacfd351e087310ea72125c
https://doi.org/10.1101/2021.11.17.468248
https://doi.org/10.1101/2021.11.17.468248
Autor:
Sarah M. Meunier, Marc G. Aucoin, M S Miller, M R D'Agostino, Michael Sasges, S J Boegel, B Petri, Michelle A. Gabriel, A Zhang, Jann C. Ang
Publikováno v:
Microbiology Spectrum
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum, Vol 9, Iss 2 (2021)
UV light, more specifically UV-C light at a wavelength of 254 nm, is often used to disinfect surfaces, air, and liquids. In early 2020, at the cusp of the COVID-19 pandemic, UV light was identified as an efficient means of eliminating coronaviruses;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450233e00d2fbfe0ecbd326a741739e1
https://doi.org/10.1128/spectrum.00537-21
https://doi.org/10.1128/spectrum.00537-21
Autor:
Sergey Yegorov, Daniel B. Celeste, Kimberly Braz Gomes, Jann C. Ang, Colin Vandenhof, Joanne Wang, Ksenia Rybkina, Vanessa Tsui, Hannah D. Stacey, Mark Loeb, Matthew S. Miller
Publikováno v:
Cell reports. Medicine. 3(2)
The induction of broadly neutralizing antibodies (bNAbs) that target the hemagglutinin stalk domain is a promising strategy for the development of "universal" influenza virus vaccines. bNAbs can be boosted in adults by sequential exposure to heterosu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dea0b026d16a3bf7d1751ba4b29393
https://pubmed.ncbi.nlm.nih.gov/35243425
https://pubmed.ncbi.nlm.nih.gov/35243425
Autor:
Ali Zhang, Zhou Xing, Allyssa Phelps, Brian D. Lichty, Uma Sankar, Xiangqian Luo, Matthew S. Miller, Sam Afkhami, Gluke Ye, Mangalakumari Jeyanathan, Jegarubee Bavananthasivam, Ramandeep Singh, Yonghong Wan, Fiona Smaill, Hannah D. Stacey, Maria Fe C. Medina, Manel Jordana, Jann C. Ang, Karen L. Mossman, Natallia Kazhdan, Anna Zganiacz, Amy Gillgrass, Joshua F E Koenig, Fuan Wang, Art Marzok, Alisha Kang
SummaryThe emerging SARS-CoV-2 variants of concern (VOC) increasingly threaten the effectiveness of current first-generation COVID-19 vaccines that are administered intramuscularly and are designed to only target the spike protein. There is thus a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c690d9571ac96fca0f1520c7da5a05cc
https://doi.org/10.1101/2021.07.16.452721
https://doi.org/10.1101/2021.07.16.452721