Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Janka Kisucka"'
Autor:
Jeonifer Garren, Hiroshi Saito, Valerie Clerin, Harald Jüppner, Janka Kisucka, Monica Reyes, Kevin J. Filipski, An Hai Nguyen
Publikováno v:
Journal of Clinical Investigation. 130:6510-6522
The sodium-phosphate cotransporter NPT2a plays a key role in the reabsorption of filtered phosphate in proximal renal tubules, thereby critically contributing to phosphate homeostasis. Inadequate urinary phosphate excretion can lead to severe hyperph
Autor:
Monty Krieger, Olivier Kocher, Tobias A. Fuchs, Denisa D. Wagner, Simon F. De Meyer, Alexander Brill, Ayce Yesilaltay, Janka Kisucka
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:1841-1847
Objective— Deep vein thrombosis (DVT) and pulmonary embolism are frequent causes of morbidity and mortality. The goal of our study was to determine whether plasma high-density lipoprotein (HDL), which inversely correlates with the risk of cardiovas
Autor:
Janka Kisucka, Anil K. Chauhan, Alexander Brill, Meghan T. Walsh, Friedrich Scheiflinger, Denisa D. Wagner
Publikováno v:
The Journal of Experimental Medicine
von Willebrand factor (VWF) levels are elevated and a disintegrin-like and metalloprotease with thrombospondin type I repeats–13 (ADAMTS13) activity is decreased in both acute and chronic inflammation. We hypothesized that by cleaving hyperactive u
Autor:
Anil K. Chauhan, Luigi De Marco, Mario Mazzucato, Francisco E. Baralle, Janka Kisucka, Meghan T. Walsh, Andrés F. Muro, Maria Rita Cozzi, Monica Battiston, Federico A. Moretti, Denisa D. Wagner
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:296-301
Objective— Fibronectin (FN) plays an important role in the formation of stable arterial thrombi at the site of vascular injury. FN containing Extra Domain A (EDA + FN) is absent from normal plasma, but elevated plasma levels of EDA + FN are found i
Autor:
Kim Frederix, Denisa D. Wagner, Bing-Qiao Zhao, Henri M. H. Spronk, Janka Kisucka, Hugo ten Cate, Erik I. Hoff, Anil K. Chauhan
Publikováno v:
Brain Research. 1185:239-245
Photochemically induced cerebral infarction has been considered a clinically relevant model for ischemic stroke. We evaluated various transgenic mice to study the role of platelet adhesion molecules in this model. Infarction to the sensorimotoric cor
Autor:
Henri M. H. Spronk, Janka Kisucka, H. Ten Cate, Denisa D. Wagner, Kim Frederix, Anil K. Chauhan
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:P-W
Autor:
Ayce Yesilaltay, Bing-Qiao Zhao, Anil K. Chauhan, Monty Krieger, Denisa D. Wagner, Janka Kisucka, Ian S. Patten
Publikováno v:
Blood. 113(23)
Cerebrovascular and cardiovascular diseases are a major cause of morbidity and mortality. Soluble P-selectin (sP-selectin) is a biomarker for platelet/endothelial activation and is considered a risk factor for vascular disease. sP-selectin enhances p
Autor:
Ayce Yesilaltay, Monty Krieger, Richard A. Van Etten, Ian S. Patten, Anil K. Chauhan, Carola A. Neumann, Denisa D. Wagner, Janka Kisucka
Publikováno v:
Circulation research. 103(6)
The peroxiredoxin (Prdx) family of antioxidant enzymes uses redox-active cysteines to reduce peroxides, lipid hydroperoxides, and peroxynitrites. Prdx1 is known to be important to protect red blood cells against reactive oxygen species and in tumor p
Autor:
Atul F. Kamath, Anil K. Chauhan, Janka Kisucka, Denisa D. Wagner, Vandana S. Dole, Diane E. Handy, Joseph Loscalzo
Publikováno v:
Blood. 107(2)
Elevated levels of plasma homocysteine (Hcy) correlate with increased risk of cardiovascular and Alzheimer diseases. We studied the effect of elevated Hcy on the blood-brain barrier (BBB) to explore the possibility of a vascular link between the 2 di
Autor:
Denisa D. Wagner, Diane E. Handy, Joseph Loscalzo, Vandana S. Dole, Janka Kisucka, Atul F. Kamath, Anil K. Chauhan
Publikováno v:
Blood. 106:3856-3856
Elevated levels of plasma homocysteine (Hcy) correlate with increased risks of cardiovascular and Alzheimer’s diseases. We studied the effect of elevated Hcy on the blood-brain barrier (BBB) to explore the possibility of a vascular link between the