Výsledky vyhledávání - "Janita, Lövgren"

Akademický článek

Time-resolved fluorescence based direct two-site apoA-I immunoassays and their clinical application in patients with suspected obstructive coronary artery disease

Autor: Priyanka Negi, Taina Heikkilä, Karoliina Vuorenpää, Emilia Tuunainen, Wail Nammas, Teemu Maaniitty, Juhani Knuuti, Jari Metso, Janita Lövgren, Matti Jauhiainen, Urpo Lamminmäki, Kim Pettersson, Antti Saraste

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

ObjectiveHigh-density lipoprotein (HDL) is a heterogeneous group of subpopulations differing in protein/lipid composition and in their anti-atherogenic function. There is a lack of assays that can target the functionality of HDL particles related to

Externí odkaz: https://doaj.org/article/d8f5248c1ad345a0a3d4f9e782875e22

Zobrazit plný text záznamu

Three two-site apoA-I immunoassays using phage expressed detector antibodies - Preliminary clinical evaluation with cardiac patients

Autor: Priyanka, Negi, Taina, Heikkilä, Terhi, Tallgren, Päivi, Malmi, Juha, Lund, Juha, Sinisalo, Jari, Metso, Matti, Jauhiainen, Kim, Pettersson, Urpo, Lamminmäki, Janita, Lövgren

Publikováno v: Journal of pharmaceutical and biomedical analysis. 194

High density lipoproteins (HDL) are a heterogenous group of subpopulations differing in protein/lipid composition and in their anti-atherogenic function. There is a lack of specific and robust assays which can target the functionality of HDL with res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d0bfe4db0c512d2226d872a93be5f8a
https://pubmed.ncbi.nlm.nih.gov/33309125

Zobrazit plný text záznamu

Next generation sequencing of all variable loops of synthetic single framework scFv-Application in anti-HDL antibody selections

Autor: Urpo Lamminmäki, Mikko Pyykkö, Jussi Salmi, Janita Lövgren, Juha-Pekka Pursiheimo

Publikováno v: New biotechnology. 33(6)

Next generation sequencing (NGS) can be applied to monitoring antibody phage display library selection processes to follow the enrichment of each individual antibody clone. Utilising the recent development of the Illumina sequencing platform enabling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec04ba19fe2a3a36a57c0a6a9034c00
https://pubmed.ncbi.nlm.nih.gov/27450754

Zobrazit plný text záznamu

Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library

Autor: Janita Lövgren, Nina Sirkka, Matti Jauhiainen, Priyanka Negi, Eeva-Christine Brockmann, Jari Metso, Paivi Malmi, Kim Pettersson, Tuomas Huovinen, Urpo Lamminmäki

Publikováno v: Clinical biochemistry. 49(6)

Objective In epidemiological studies plasma high density lipoprotein cholesterol (HDL-C) levels are found to correlate inversely with atherosclerotic cardiovascular events. HDL consists of different subpopulations and they vary in their anti-atheroge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e13d4f03627729fe9397763a3e99be
https://pubmed.ncbi.nlm.nih.gov/26656638

Zobrazit plný text záznamu

Prostate-specific antigen and other prostate-derived proteases cleave IGFBP-3, but prostate cancer is not associated with proteolytically cleaved circulating IGFBP-3

Autor: Markku Seppälä, Patrik Finne, Riitta Koistinen, Janita Lövgren, Annukka Paju, Hannu Koistinen, Ulf-Håkan Stenman, Ping Wu

Publikováno v: The Prostate. 50:112-118

BACKGROUND Proteolysis of insulin-like growth factor-binding proteins (IGFBPs) may increase IGF-mediated growth stimulation and development of cancer in the organs producing large amounts of proteases, such as the prostate. METHODS We studied proteol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68a57d740a42bb8b5747e78132253820
https://doi.org/10.1002/pros.10039

Zobrazit plný text záznamu

Activation of latent protease function of pro-hk2, but not pro-PSA, involves autoprocessing

Autor: Samuel R. Denmeade, Hans Lilja, Saeed R. Khan, Janita Lövgren, John T. Isaacs

Publikováno v: The Prostate. 48:122-126

BACKGROUND: Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of an extensive kallikrein family of proteases. Both proteases are secreted as zymogens or proenzymes containing a seven amino acid propeptide that must be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d87c3f21a60aaaa9ae03470cf5f78714
https://doi.org/10.1002/pros.1088

Zobrazit plný text záznamu

Production and activation of recombinant hK2 with propeptide mutations resulting in high expression levels

Autor: Hans Lilja, Sha Tian, Janita Lövgren, Åke Lundwall, Matti Karp

Publikováno v: European Journal of Biochemistry. 266:1050-1055

Human glandular kallikrein 2 (hK2) is a serine protease expressed mainly by the prostate gland with 80% identity in primary structure to prostate specific antigen (PSA). hK2 has proven to be a useful marker of prostate cancer which can be used in com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fafb5ddfb106df62c16ceb3bbe8f80e6
https://doi.org/10.1046/j.1432-1327.1999.00946.x

Zobrazit plný text záznamu

Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors

Autor: Janita Lövgren, Kalervo Airas, Hans Lilja

Publikováno v: European Journal of Biochemistry. 262:781-789

Human glandular kallikrein 2 (hK2) is a serine protease expressed by the prostate gland with 80% identity in primary structure to prostate-specific antigen (PSA). Recently, hK2 was shown to activate the zymogen form of PSA (proPSA) in vitro and is li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24c8b92afce4b93f8bbdfeb232c3129
https://doi.org/10.1046/j.1432-1327.1999.00433.x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání